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501.
The effects of a specific presynaptic cholinergic antagonist, toosendanin, on memory formation following a passive avoidance training experience in day-old chicks was investigated. Bilateral injection of toosendanin into the neostriatal/hyperstriatal region of the chick forebrain produced memory impairment in a dose-dependent manner. Retention deficits were apparent from 20 min following training in chicks treated with toosendanin, regardless of the injection time relative to training. Chicks that received injections of the drug at corresponding times prior to retention tests showed normal retention levels, suggesting that toosendanin has no effect on performance and memory retrieval. These results indicate an involvement of cholinergic transmission during an early stage of memory formation. 相似文献
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506.
B. M. Bennett 《Psychometrika》1967,32(4):419-423
A rank testR
n has been proposed by Cronholm and Revusky which in effect increases the number of observations per subject by the device of randomly assigning a subject to a treated group in each of a series of sub-experiments. In this note further results on the asymptotic normality of theR
n test are discussed both under the null hypothesisH
0 of randomness and under a class of alternatives toH
0. The limiting power of the test is also discussed. 相似文献
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508.
Working memory load differentially affects tip-of-the-tongue states and feeling-of-knowing judgments
Schwartz BL 《Memory & cognition》2008,36(1):9-19
Tip-of-the-tongue states (TOTs) are judgments of the likelihood of imminent retrieval for items currently not recalled, whereas feeling-of-knowing judgments (FOKs) are predictions of successful recognition for items not recalled. The assumption has been that similar metacognitive processes dictate these similar judgments. In Experiment 1, TOTs and FOKs were compared for general information questions. Participants remembered four digits (working memory load) during target retrieval for half of the questions, and there was no memory load for the other questions. Working memory did not affect recall but decreased the number of TOTs and increased FOKs. In Experiment 2, participants maintained six digits during retrieval. TOTs decreased in the working memory condition, but FOKs remained constant. Experiment 3 replicated the results of Experiment 2 while asking for FOKs for recall. In each of the first three experiments, positive metacognitive judgments also affected working memory performance, supporting the idea that working memory and metamemory use similar monitoring processes. In Experiment 4, visual working memory did not affect TOTs or FOKs. The data support a view that TOTs and FOKs are separable metacognitive entities. 相似文献
509.
Lauren Bennett Cattaneo 《Sex roles》2008,58(7-8):592-594
510.
Vital exhaustion has been implicated in the development and progression of cardiovascular disease. In addition, elevated levels of fibrinogen and D-dimer have been associated with an increased risk of cardiovascular disease. Some studies have suggested that fibrinogen and D-dimer are associated with acute, chronic, and perceived stress. In this issue, Kudielka et al examine the relationship between circulating fibrinogen and D-dimer levels and vital exhaustion in a cross-sectional study of middle-aged teachers in Germany, to examine the plausible link between chronic stress and the development of cardiovascular disease. This commentary discusses the limited available evidence of the mechanisms responsible for the association between vital exhaustion and the development of cardiovascular disease and highlights the limitations of previous research and discusses future directions. 相似文献