Cognitive and neural consequences of memory suppression in major depressive disorder

Negative biases in cognition have been documented consistently in major depressive disorder (MDD), including difficulties in the ability to control the processing of negative material. Although negative information-processing biases have been studied using both behavioral and neuroimaging paradigms, relatively little research has been conducted examining the difficulties of depressed persons with inhibiting the retrieval of negative information from long-term memory. In this study, we used the think/no-think paradigm and functional magnetic resonance imaging to assess the cognitive and neural consequences of memory suppression in individuals diagnosed with depression and in healthy controls. The participants showed typical behavioral forgetting effects, but contrary to our hypotheses, there were no differences between the depressed and nondepressed participants or between neutral and negative memories. Relative to controls, depressed individuals exhibited greater activity in right middle frontal gyrus during memory suppression, regardless of the valence of the suppressed stimuli, and differential activity in the amygdala and hippocampus during memory suppression involving negatively valenced stimuli. These findings indicate that depressed individuals are characterized by neural anomalies during the suppression of long-term memories, increasing our understanding of the brain bases of negative cognitive biases in MDD.     

Speaking two “Languages” in America: A semantic space analysis of how presidential candidates and their supporters represent abstract political concepts differently

In this article we report a computational semantic analysis of the presidential candidates’ speeches in the two major political parties in the USA. In Study One, we modeled the political semantic spaces as a function of party, candidate, and time of election, and findings revealed patterns of differences in the semantic representation of key political concepts and the changing landscapes in which the presidential candidates align or misalign with their parties in terms of the representation and organization of politically central concepts. Our models further showed that the 2016 US presidential nominees had distinct conceptual representations from those of previous election years, and these patterns did not necessarily align with their respective political parties’ average representation of the key political concepts. In Study Two, structural equation modeling demonstrated that reported political engagement among voters differentially predicted reported likelihoods of voting for Clinton versus Trump in the 2016 presidential election. Study Three indicated that Republicans and Democrats showed distinct, systematic word association patterns for the same concepts/terms, which could be reliably distinguished using machine learning methods. These studies suggest that given an individual’s political beliefs, we can make reliable predictions about how they understand words, and given how an individual understands those same words, we can also predict an individual’s political beliefs. Our study provides a bridge between semantic space models and abstract representations of political concepts on the one hand, and the representations of political concepts and citizens’ voting behavior on the other.     

Conjunction in simulated railway signals: a cautionary note

Train drivers routinely perform visual search tasks to locate combinations of coloured signals controlling their progress, and are required to make discrete decisions on the basis of what they see. Two studies are reported which examine the performance of students under conditions that simulate critical aspects of United Kingdom train drivers' signal‐response task. The most crucial cautionary signal, the single yellow signal used to alert a transition to potentially hazardous situations, was responded to more slowly than other signal types. A longer processing time was found whether (Study 2) or not (Study 1) the signal appearance was accompanied by the auditory warning signal train drivers encounter under actual driving conditions. The results are consistent with predictions from Treisman and Gelade's ( 1980 ) Feature Integration Theory, and the implications for signal sighting practice are discussed. Copyright © 2005 John Wiley & Sons, Ltd.     

Can Facilitation Imagery Alter the Effects of Semantic Priming?

This study examined if task motivational imagery suggestions could facilitate a semantic priming effect, relative to general relaxation suggestions and no specific suggestions; and if the participants’ hypnotizablity moderated the effects of the three types of instructions. Participants (n = 127) were assigned randomly in groups to one of the three instructional conditions (imagery, relaxation, or control) and two versions of a stimulus list for counterbalancing. A 3-way analysis of variance suggested that the semantic priming effect was found to be stronger for stimulus list version 2 than for version 1. A stronger semantic priming effect was found for the high, relative to the low and medium, hypnotizable groups. When medium hypnotizable participants were excluded, an instructional group X hypnotizability group interaction was found for list 1 suggesting that while the low hypnotizable participants benefited more from the relaxation suggestion, the high hypnotizables benefited more from the imagery instruction. The results suggest that imagery instructions may moderate automatic processes for highly hypnotizable individuals.     

Adolescents’ Perceptions of Family Connectedness,Intrinsic Religiosity,and Depressed Mood

Using a sample of 248 ninth and tenth grade students at public high schools, we examined adolescents’ perceptions of family connectedness, intrinsic religiosity, and adolescents’ gender in relation to depressed mood and whether intrinsic religiosity and gender moderated the association of aspects of family connectedness to adolescent depressed mood. Using hierarchical multiple regression analyses we tested models separately for three forms of family connectedness (overall family cohesion, mothers’ support, and fathers’ support), intrinsic religiosity, and depressed mood. In each model, family connectedness was negatively associated with depressed mood. Intrinsic religiosity was not significantly associated with depressed mood. However, in the mothers’ support model, both a two-way interaction (mothers’ support × intrinsic religiosity) and a three-way interaction (adolescents’ gender × mothers’ support × intrinsic religiosity) were significantly related to depressed mood. In the two-way interaction, higher intrinsic religiosity was a moderator, strengthening the association between mothers’ support and depressed mood. In the three-way interaction, gender differences were found. For boys, high intrinsic religiosity strengthened the association between mothers’ support and depressed mood. Among girls, when mothers’ support was low, intrinsic religiosity provided an additional source of connectedness in protecting against depressed mood. Our findings show that connectedness in overall family systems, mother–adolescent subsystems, and father–adolescent subsystems are all important to emotional resilience in adolescents by protecting against depressed mood. Future studies of adolescent religiosity may benefit from including diverse forms of family connectedness in understanding the protective processes provided by aspects of religiosity in promoting adolescents’ emotional resilience.     

Daily suppression of discrete emotions during the work of police service workers and criminal investigation officers

The aim of the present research among Dutch police officers was to examine whether fluctuations in emotional job demands predict exhaustion through the suppression of discrete emotions. A first diary study (N =25) tested how the suppression of discrete emotions is related to exhaustion at the end of the work shift of police call-center service workers. Results revealed that suppressing anger was positively related to exhaustion at the end of a work shift, whereas suppressing happiness was not. A second study (N=41) among criminal investigation officers showed that the emotions anger, abhorrence, and sadness were among the most common negative emotions that were suppressed as part of the emotional labor of this specialized occupational group. Results of a third (diary) study (N=39) confirmed that emotional dissonance and more particularly the suppression of abhorrence mediated the relationship between emotional job demands and exhaustion at the end of a work shift.     

Back to the future: autobiographical planning and the functionality of mind-wandering

Given that as much as half of human thought arises in a stimulus independent fashion, it would seem unlikely that such thoughts would play no functional role in our lives. However, evidence linking the mind-wandering state to performance decrement has led to the notion that mind-wandering primarily represents a form of cognitive failure. Based on previous work showing a prospective bias to mind-wandering, the current study explores the hypothesis that one potential function of spontaneous thought is to plan and anticipate personally relevant future goals, a process referred to as autobiographical planning. The results confirm that the content of mind-wandering is predominantly future-focused, demonstrate that individuals with high working memory capacity are more likely to engage in prospective mind-wandering, and show that prospective mind-wandering frequently involves autobiographical planning. Together this evidence suggests that mind-wandering can enable prospective cognitive operations that are likely to be useful to the individual as they navigate through their daily lives.     

Shape, color and the other-race effect in the infant brain

The 'other-race' effect describes the phenomenon in which faces are difficult to distinguish from one another if they belong to an ethnic or racial group to which the observer has had little exposure. Adult observers typically display multiple forms of recognition error for other-race faces, and infants exhibit behavioral evidence of a developing other-race effect at about 9 months of age. The neural correlates of the adult other-race effect have been identified using ERPs and fMRI, but the effects of racial category on infants' neural response to face stimuli have to date not been described. We examine two distinct components of the infant ERP response to human faces and demonstrate through the use of computer-generated 'hybrid' faces that the observed other-race effect is not the result of low-level sensitivity to 3D shape and color differences between the stimuli. Rather, differential processing depends critically on the joint encoding of race-specific features.     

Systematic influence of gaze position on pupil size measurement: analysis and correction

Cognitive effort is reflected in pupil dilation, but the assessment of pupil size is potentially susceptible to changes in gaze position. This study exemplarily used sentence reading as a stand-in for paradigms that assess pupil size in tasks during which changes in gaze position are unavoidable. The influence of gaze position on pupil size was first investigated by an artificial eye model with a fixed pupil size. Despite its fixed pupil size, the systematic measurements of the artificial eye model revealed substantial gaze-position-dependent changes in the measured pupil size. We evaluated two functions and showed that they can accurately capture and correct the gaze-dependent measurement error of pupil size recorded during a sentence-reading and an effortless z-string-scanning task. Implications for previous studies are discussed, and recommendations for future studies are provided.     

A controlled trial of an internet-based intervention program for cannabis users

In the last decade, several programs for the treatment of cannabis-related disorders were developed. Until now, no information is available on the efficacy of Internet-based counseling approaches for this target group. This article describes the evaluation of "quit the shit," a web-based intervention developed to help young people to quit or reduce their cannabis use significantly. Cannabis users seeking web-based treatment were included in a two-arm controlled trial conducted on a website for drug-related information and prevention. After the baseline assessment, members of the treatment condition were randomized to a 50-day intervention program. Other trial participants were put on a waiting list. A post-test was conducted 3 months after randomization. Of all 1,292 subjects included in the trial, a total of 206 participants took part at the post-test. Per-protocol- and intention-to-treat analyses were conducted. Members of the treatment condition showed a significantly stronger reduction in cannabis use (primary outcome) than the control group. In the per-protocol analyses, moderate-to-strong effects were found for the reduction of the frequency and the reduction of the quantity of consumed cannabis. Small-to-moderate effects were observed on the secondary outcomes (use-related self-efficacy, anxiety, depression, and life satisfaction). Despite limitations concerning the interpretation of the results, the intervention seems to offer an effective treatment option for persons with cannabis-related problems.