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141.
Frontostriatal networks play critical roles in grounding action semantics and syntactic skills. Indeed, their atrophy distinctively disrupts both domains, as observed in patients with Huntington's disease (HD) and Parkinson's disease, even during early disease stages. However, frontostriatal degeneration in these conditions may begin up to 15 years before the onset of clinical symptoms, opening avenues for pre‐clinical detection via sensitive tasks. Such a mission is particularly critical in HD, given that patients’ children have 50% chances of inheriting the disease. Against this background, we assessed whether deficits in the above‐mentioned domains emerge in subjects at risk to develop HD. We administered tasks tapping action semantics, object semantics, and two forms of syntactic processing to 18 patients with HD, 19 asymptomatic first‐degree relatives, and sociodemographically matched controls for each group. The patients evinced significant deficits in all tasks, but only those in the two target domains were independent of overall cognitive state. More crucially, relative to controls, the asymptomatic relatives were selectively impaired in action semantics and in the more complex syntactic task, with both patterns emerging irrespective of the subjects’ overall cognitive state. Our findings highlight the relevance of these dysfunctions as potential prodromal biomarkers of HD. Moreover, they offer theoretical insights into the differential contributions of frontostriatal hubs to both domains while paving the way for innovations in diagnostic procedures.  相似文献   
142.
The use of personality disorder (PD) categories persists, despite the evidence against them. An often overlooked reason for this is the fact that the true structure underlying the Diagnostic and Statistical Manual of Mental Disorders (DSM) taxonomy is still unknown: We cannot be certain which disorders are valid, and which ones are arbitrary mixtures of heterogeneous traits. To address this gap, we factor analyzed the Personality Diagnostic Questionnaire (PDQ–4+; Hyler, 1994 Hyler, S. E. (1994). PDQ–4+ Personality Diagnostic Questionnaire–4+. New York, NY: New York State Psychiatric Institute. [Google Scholar]) at the criterion level in a mixed clinical and nonclinical sample of 2,519 individuals. The resulting structure was more similar to current dimensional taxonomies than to the DSM classification at all hierarchical levels. Whereas paranoid and antisocial PDs—and to a lesser extent avoidant, dependent, depressive, and schizoid PDs—were fairly homogeneous, all other disorders turned out to be combinations of 2 or 3 unrelated dimensions. Our results strongly support the structure of empirically based dimensional taxonomies and relocate DSM criteria within this emerging framework, thus contributing to preserving much of the knowledge accumulated to date.  相似文献   
143.
HIV testing is important in terms of prevention and treatment. However, HIV testing rates in the Spanish general population remains low. Therefore, HIV testing promotion constitutes a key issue. A high level of knowledge about HIV/AIDS is associated with having been tested for HIV. The general aim of this study was to determine the prevalence of people who had ever been tested for HIV in Spain. The sample consisted of 1,106 participants from the general population — 60.0% females and 40.0% males — aged between 17 and 55 years old. The assessment instruments were a questionnaire on sociodemographic data and HIV testing, a scale of knowledge about STIs and HIV/AIDS, and a scale of concern about STIs/HIV. Results showed that greater knowledge about STIs and HIV was associated with a greater likelihood of being tested for HIV (OR = .77; 95.0% CI = .73–.82; p < .05). In addition, higher concern about HIV/AIDS decreased the likelihood of not having been tested for HIV (OR = .87; 95.0% CI = .83–.92; p < .05). In fact, the higher participants concern about STIs was, the lower their likelihood of not having been tested for HIV was (OR = .87; 95.0% CI = .83–.91; p < .05). It is necessary to promote HIV testing in the general population as well as to consider their socio-demographic and psychological characteristics.  相似文献   
144.
We aimed to investigate the relationship of religious beliefs and forgiveness in diabetic patients with various sociodemographic characteristics, emotional problems and glycaemic control. The study comprises 100 patients diagnosed with type 2 DM. We used a data collection form, the Scale of Forgiveness and Religiosity (SFR), Problem Areas in Diabetes Scale (PAID), Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI) and the Audit of Diabetes-Dependent Quality of Life (ADDQoL). We also recorded blood glucose and HbA1c test results. A statistically significant relationship was determined only between the scores of the STAI-I and the religious belief scales (r = 0.198, p = 0.049). A statistically significant negative relationship was determined between the forgiveness scale points and the BDI (r = 0.326, p = 0.001), the STAI-II (r = 0.308, p = 0.002) and PAID (r = 0.313, p = 0.001) and a positive correlation with ADDQoL (r = 0.284, p = 0.004). To conclude, forgiveness by patient himself or others reduced the emotional problems which were experienced related to diabetes by reducing stress levels and could increase quality of life.  相似文献   
145.
The purpose of this study was to analyse the relationship between high social anxiety, academic goals and learning strategies in a sample of 2,022 (51.1% male) Spanish adolescents aged 12–16. The Social Phobia and Anxiety Inventory (SPAI), Achievement Goal Tendencies Questionnaire (AGTQ) and Learning and Studies Skills Strategies Inventory — High School Version (LASSI-HS) were used to assess the variables. The results showed no statistically significant differences in goal orientations between students with and without high social anxiety. However, students with high social anxiety used learning strategies significantly less. In addition, the logistic regression results indicated that high social anxiety acts as a significant predictor for setting social reinforcement goals and learning and study strategies.  相似文献   
146.
This article presents a brief history of the development of the Western university and the individuation of disciplines. It discusses the phenomenal specialization that has occurred since the 19th century, and the lack of correlative synthesis of the disparate fields of knowledge, which increasingly has come under critique. We explore the transdisciplinary experience that has been developing over the last few years in the University of Veracruz, in particular with regards to the Program for Transdisciplinarity, Dialogue of Knowing Styles and Sustainability, a co-construction of a set of actions that foster a transformation of university academics by means of deep dialogue and a transdisciplinary re-learning process.  相似文献   
147.
The history of organizations and collectives is something alive. It is a network of memories, actions, collaborations, dreams, encounters, and disconnections that live within each of its members. The EcoDialogue Center is an academic space of the University of Veracruz for promoting dialogue between disciplines. In this article we are presenting the stories, both personal and collective, and the values and ideals that create our Center. We are using this opportunity to reflect on the cultural, geographical, emotional, intellectual, and societal conditions that have allowed this innovative process within the rules and customs of a university.  相似文献   
148.
In this essay, I focus on two biographical works by Hannah Arendt and Simone de Beauvoir that I read as political texts: Rahel Varnhagen: The Life of a Jewess (Arendt 1957 ) and “Must We Burn Sade?” (Beauvoir 2012 ). Reading Arendt's Varnhagen and Beauvoir's “Sade” side by side illuminates their shared preoccupation with lived experience and their common political premises: the antagonism between freedom and sovereignty, and the centrality of action and constructive relations with others. My argument is that these texts constitute an original style of political thinking, which I call politico‐biographical hermeneutics, or reading the life of others as exercises in political theory. Politico‐biographical hermeneutics, as I take it, is not a systematic methodology, but an approach to interpreting sociopolitical forces as they come to bear and are embodied and inscribed in the lived experiences, struggles, and works of representative or exemplary individuals. This approach identifies the political lessons of lived experience and supports one of the central claims of feminist philosophy, namely, that the personal and the political are not antithetical, but relational.  相似文献   
149.
150.
Four experiments examined people's responses to intergroup violence either committed or suffered by their own group. Experiment 1 demonstrated that Serbs who strongly glorified Serbia were more supportive of future violence against, and less willing to reconcile with, Bosniaks after reading about Serbian victimization by Bosniaks rather than Serbian transgressions against Bosniaks. Replicating these effects with Americans in the context of American–Iranian tensions, Experiment 2 further showed that demands for retributive justice explained why high glorifiers showed asymmetrical reactions to ingroup victimization vs. perpetration. Again in the Serb and the American context, respectively, Experiments 3 and 4 demonstrated that post‐conflict international criminal tribunals can help satisfy victim group members' desire for retributive justice, and thereby reduce their support for future violence and increase their willingness to reconcile with the perpetrator group. The role of retributive justice and the use of international criminal justice in intergroup conflict (reduction) are discussed.  相似文献   
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