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111.
Ahmadi S Zarrindast MR Nouri M Haeri-Rohani A Rezayof A 《Neurobiology of learning and memory》2007,88(3):352-358
The interaction of opiate, cholinergic, glutamatergic and (possibly) dopaminergic inputs in the ventral tegmental area (VTA) influencing a learned behavior is certainly a topic of great interest. In the present study, the effect of intra-VTA administration of N-methyl-d-aspartate (NMDA) receptor agents on nicotine's effect in morphine state-dependent learning was investigated. An inhibitory avoidance (IA) task was used for memory assessment in male Wistar rats. Subcutaneous (s.c.) administration of morphine (5 and 7.5mg/kg) immediately after training decreased IA response on the test day, which was reinstated by pre-test administration of the same doses of the opioid; this is known as state-dependency. Moreover, pre-test administration of nicotine (0.2, 0.4 and 0.6 mg/kg, s.c.) also reversed the decrease in IA response because of post-training morphine (5mg/kg). Here, we also show that when infused into the VTA before testing, NMDA (0.01 and 0.1 microg/rat) reverse the post-training morphine effect on memory. In addition, the sub-effective doses of NMDA (0.0001 and 0.001 microg/rat) in combination with a low dose of nicotine (0.1mg/kg) which had no effects by themselves, synergistically improved retrieval of IA memory on the test day. In contrast, pre-test administration of a competitive NMDA receptor antagonist D-AP5 (0.5, 1 and 2 microg/rat) which had no effect alone prevented the nicotine reversal of morphine effect on memory. Our data indicate that NMDA receptors in the VTA are involved in the reversing effect of nicotine on morphine induced state-dependency. 相似文献
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As scholars, remembering the historical past in one's area of study provides a foundation for purposefully pursuing knowledge. As individuals, remembering our personal past provides direction and purpose in everyday life. Taken together, these percepts provide the impetus for the current paper, which traces the contributions of six early pioneers who wrote about how humans remember their personal past. Analysis demonstrates how their historical ideas support current literatures focused on the personal past: reminiscence‐based mental health interventions, the adaptive psychosocial functions of autobiographical remembering, and the construction of identity as a life story. Three future research directions are also briefly presented: the human ability for mental ‘time travel’, a lifespan approach to remembering the personal past, and reflection on one's past as a route to wisdom. Understanding the human phenomenon of remembering the personal past has long‐standing historical roots that continue to stimulate basic and applied research. Copyright © 2013 John Wiley & Sons, Ltd. 相似文献
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This study examines the representations of male and female social actors in selected Iranian EFL (English as a Foreign Language) textbooks. It is grounded in Critical Discourse Analysis and uses van Leeuwen’s Social Actor Network Model to analyze social actor representations in the gendered discourses of compulsory heterosexuality. Findings from the analysis show that the representations endorse the discourse of compulsory heterosexuality which is an institutionalized form of social practice in Iran. Three male and three female students were interviewed to find out what they think about these representations. Their responses with regard to whether they think textbooks should also include representations of other forms of sexuality were non-committal and vague. To them LGBT people are the “Other” practicing a form of sexuality that is not normal. Such exclusions could obscure the reality regarding the existence of such gender identities and represent the world in a particular manner. 相似文献
116.
Trauma,Emotions, and Memory in World Politics: The Case of the European Union's Foreign Policy in the Middle East Conflict
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This article focuses on the impact of emotions on the European Union (EU)'s international identity and agency in the context of the memory of trauma. Emotions are understood as performances through which an actor expresses itself to others while constructing its identity, creating its agency, and potentially affecting the social order. It is argued that the memory of trauma is translated into EU foreign policy practice through emotional performances of EU representatives. Empirically, we explore this impact in relation to the EU's engagement in the Israel‐Palestinian prolonged conflict that has many underlying emotions linked with past traumatic experiences. By doing so, we aim to instigate a discussion between the emotions literature in International Relations and the European Union studies literature to nuance understanding of the politics of emotions that increasingly constrain what kind of a global actor the EU actually is or can become. 相似文献
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Gad Ibtissam Tan Xiao-Wei Cherie Williams Sarah Itawi Sally Dahbour Layth Rotter Zachary Mitro Graham Rusch Courtney Perkins Sara Ali Imran 《Journal of religion and health》2022,61(2):1120-1138
Journal of Religion and Health - According to many studies, addressing the religious and spiritual (R/S) needs of patient's increase patient satisfaction. One area of interest is how patient... 相似文献
118.
Moradi AR Abdi A Fathi-Ashtiani A Dalgleish T Jobson L 《Behaviour research and therapy》2012,50(6):435-441
This study examined the recollection of autobiographical material in memory among Iranian military veterans with and without posttraumatic stress disorder (PTSD), and healthy non-trauma-exposed control subjects. Participants completed the Autobiographical Memory Test, Autobiographical Memory Interview (counterbalanced), Impact of Event Scale-Revised, Beck Depression Inventory-II, Wechsler Memory Scale-III and Wechsler Adult Intelligence Scale-Revised. The PTSD group generated fewer specific episodic and semantic details of autobiographical memory compared to the non-PTSD and control groups. Working memory did not significantly moderate the relationship between PTSD diagnosis and reduced autobiographical memory specificity but did moderate the relationship between PTSD diagnosis and semantic recall; semantic memory recall was not significantly related to working memory ability for those with PTSD but was related to working memory ability for trauma survivors without PTSD. While the data provide some support for the expectation that higher working memory ability is associated with an increased ability to retrieve specific memories (i.e. semantic memory recall in those without PTSD), the findings are also consistent with the view that for those with PTSD the demands on working memory required for affect regulation cancel out this influence of working memory in augmenting access to specific memories. 相似文献
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The learning of new information and recall of that information presumably involves modification of and access to shared circuitry in the brain. However, learning and recall may involve the activation of distinct parts of that circuitry, according to the quite distinct functional differences between these two processes. Previously we examined neuronal activation following learning of context fear conditioning. Using the Fos-Tau-LacZ (FTL) transgenic mouse to label activated neurons, we identified a number of distinct populations of neurons in amygdala and hypothalamus which showed learning specific activation. These populations of neurons showed much less activation following recall. Here we ask what populations of neurons might be specifically activated following recall. We trained mice in context fear conditioning, and then looked at FTL activation following recall of context fear. We identified a number of populations of neurons which showed recall specific activation in nucleus accumbens shell, the anterio-medial bed nucleus of stria terminalis, the anterior commissural nucleus and the periventricular hypothalamic nucleus. These were all different populations of neurons compared with those activated following context fear learning. These different functional activation patterns occurring between learning and recall may reflect the different brain functions occurring between these two memory related processes. 相似文献