Genetic moderation of contextual effects on negative arousal and parenting in African-American parents

A three-stage context amplification model was tested with a sample of 345 African-American parent-child dyads. The model combined the conceptual structure of stress generation with recent findings regarding genetic susceptibility. Because the 7R + allele of the dopamine transporter (DRD4) has the potential to enhance contextual priming and arousal, this allele was examined as a potential moderator of each stage of the amplification process. Particular attention was given to the hypothesized influence of parental negative arousal on valence of parent-child interactions. The literature on genetic susceptibility led to the hypothesis that DRD4 would moderate each stage of the model in a "for better or for worse" manner. The model was partially supported. DRD4 moderated effects at all three stages of the model and, as hypothesized, DRD4 moderated contextual effects on negative arousal in a "for better or for worse" manner. Effects on parent-child interaction, however, were moderated in a "for worse" manner only. These results indicate that parenting interactions may amplify the effects of positive and negative contexts in a stress-generating manner, and that a susceptibility framework captures the way in which DRD4 moderates the impact of context on negative arousal.     

Sometimes a Bear is Just a Bear: No Evidence of Nonclinical Adult Toy Animal Ownership Indicating Emotion Dysregulation

Although some studies of clinical populations suggest an association of adult toy animal ownership with personality disorder, studies of nonclinical populations have been lacking. In a nonclinical young adult sample (N?=?148), we found no association of toy animal ownership with use of immature, mature, or neurotic defense mechanisms; avoidant or anxious attachment style; trait conscientiousness; heart rate variability (an index of self-regulatory strength); or social desirability responding. The results do not provide evidence for an association of adult nonclinical toy animal ownership with psychological or psychophysiological indices of immaturity, conscientiousness, insecure attachment, or lack of self-regulatory strength.     

Intervention Induced Changes in Perceptions of Parenting and Risk Opportunities Among Rural African American

A randomized prevention trial was conducted contrasting families who took part in the Strong African American Families Program (SAAF), a preventive intervention for rural African American parents and their 11-year-olds, with control families. The trial, which included 671 families, indicated that intervention-induced changes occurred in intervention-targeted parenting and youth behavior, as well as youth initiation of alcohol use and sexual activity. Four waves of data collected were obtained at pretest, 3-month post-test, 29 month long-term follow up; and 65 month long-term follow up. Three data points were selected and analyzed in the current study: pretest, post-test, and 65 month long-term follow up to capture the sustainability of SAAF during three critical developmental stages—middle childhood, early adolescence, and late adolescence. Intervention-induced changes in parenting mediated the effect of intervention-group influences on changes in the onset and escalation of alcohol use and sexual activity over 65 months through its positive influence on youths’ perceptions and internalization of parental norms and resistance to engaging in risk opportunities. These findings highlight the potential for family-based prevention programs to enhance positive developmental outcomes to reduce HIV-related risk behaviors among rural African American youth.     

Emotional Reactions and Attitudes Prior to In Vitro Fertilization: An Inter-Spouse Study

In this study, spouse's emotional responses and attitudes to in vitro fertilization (IVF) treatment were examined. The participants were 113 childless couples who suffered from infertility of unknown or mechanical (women) cause. Both partners were evaluated prior to IVF treatment. Incompatible emotional responses and attitudes to the treatment between the partners usually reflected the men reporting less distress and worries than women. Women had significantly higher state and trait anxiety and depression scores than normative levels, irrespective of whether they were successful in conceiving. Husbands of conceiving women scored higher on depression than husbands of nonconceiving women. The nonconceiving husbands had depression and trait anxiety scores significantly lower than the normative level. In addition, high emotional responses to the treatment, especially in men, were positively associated with treatment success. Recommendations for family assessment and counseling are suggested on the basis of these results.     

Attentional attraction of receptive fields can explain spatial and temporal effects of attention

A multitude of attentional effects were found at both the neural and behavioural levels of perception; however, the nature of the attentional mechanism is an unsettled issue. It is typically assumed that the fundamental impact of attention is enhancement of neuronal responses, but some attentional effects are difficult to explain by such gain modulations. Here we offer a different view: We suggest that the most fundamental impact of attention is the attraction (shift) of receptive fields towards the attended location. We further show, both conceptually and by model simulations, that this attraction of receptive fields can explain a diverse range of attentional effects, spatial as well as temporal, linking physiological measurements at the unit level with psychophysical observations (e.g., enhanced contrast sensitivity, enhanced spatial resolution, the Mexican-hat profile of attention, prolonged perceived duration, prior entry, degraded temporal resolution).     

Religion and bioethics: toward an expanded understanding

Before asking what U.S. bioethics might learn from a more comprehensive and more nuanced understanding of Islamic religion, history, and culture, a prior question is, how should bioethics think about religion? Two sets of commonly held assumptions impede further progress and insight. The first involves what “religion” means and how one should study it. The second is a prominent philosophical view of the role of religion in a diverse, democratic society. To move beyond these assumptions, it helps to view religion as lived experience as well as a body of doctrine and to see that religious differences and controversies should be welcomed in the public square of a diverse democratic society rather than merely tolerated.     

Preferred perceptual tempo for sound sequences: comparison of adults, children, and infants

Previous motor and perceptual tasks have found optimal processing for sound sequences of a rate of around 600 msec. IOI (Interonset Interval). This zone of optimal processing (the rate at which discrimination is optimal) slows with age and is also found with infants. The current work investigated whether listeners "prefer" sequences at the rate for which they demonstrate optimal processing. In the present study, three experiments were done. Exp. 1 measured tempo preferences in adults who listened to pairs of isochronous sound sequences varying in tempo (from 100- to 1500-msec. IOI) and were required to indicate which they preferred. As expected, highest preferences were expressed for the intermediate tempi, supporting the hypothesis of a zone of preferred tempi comparable to the zone of optimal processing. Moreover, this preference for intermediate tempi was not affected by the temporal context (absence of differences between a fast, a slow, and a wide set of tempi). In Exp. 2, the same procedure was applied to 6- and 10-yr.-olds. Children in both groups had systematic preferences for the fastest tempi within a set, and the older children generally preferred slower sequences. Exp. 3 used a preference paradigm for sound sequences with 4-mo.-old infants, comparing sequences of 100- vs 300-msec. IOI, 300- vs 900-msec. IOI, and 100- vs 900-msec. IOI. No systematic tempo preferences were observed. We conclude that tempo discrimination and tempo preference may have some commonality (perhaps related to a zone of optimal processing), especially in adults, but that they also involve quite distinct processes which undergo different developmental sequences. Whereas adults prefer what they process the best, children prefer what is fastest (and therefore more attention-getting), and we have not been able to detect preferences in infants.     

“The Smarts That Counts?”: Psychologists' Decision-Making in Personnel Selection

An exploratory approach was taken to examine personnel psychologists' use of sources of information when making a decision regarding candidates' fit to managerial positions. The main focus was on the process, based on actual information used to make real-life decisions about real-life candidates. Different types of information, available to the psychologists were used to predict their actual final decision regarding a sample of 434 managerial candidates. Results suggest a preference to indices of cognitive skills in making decisions about candidates. It seems that even when other non-cognitive indices were used, they were tainted by the cognitive indices, suggesting a halo effect. Implications for practice and further research are discussed.     

Intellectual property and biotechnology: the U.S. internal experience--Part II

Continuing the discussion begun in the March 2006 issue of the Kennedy Institute of Ethics Journal, this paper further documents the failure of the United States to adequately consider possible modifications in the traditional robust system of intellectual property rights as applied to biotechnology. It discusses concrete suggestions for alternative disclosure requirements, for exemptions for research tools, and for improved access to clinical advances. In each of these cases, the modifications might be more responsive to the full set of relevant values.     

Economic pressure in African American families: a replication and extension of the family stress model

This study of 422 two-caregiver African American families, each with a 10-11-year-old focal child (54% girls), evaluated the applicability of the family stress model of economic hardship for understanding economic influences on child development in this population. The findings generally replicated earlier research with European American families. The results showed that economic hardship positively relates to economic pressure in families. Economic pressure was related to the emotional distress of caregivers, which in turn was associated with problems in the caregiver relationship. These problems were related to disrupted parenting practices, which predicted lower positive child adjustment and higher internalizing and externalizing symptoms. The results provide significant support for the family stress model of economic hardship and its generalizability to diverse populations.