Increased cognitive problem reporting after information about chemotherapy-induced cognitive decline: The moderating role of stigma consciousness

Objective: Information about treatment side effects can increase their occurrence; breast cancer (BC) patients showed increased cognitive problem reporting (CPR) and decreased memory performance after information about cognitive side effects. The current study extends previous research on adverse information effects (AIE) by investigating (a) risk factors, (b) underlying mechanisms and (c) an intervention to reduce AIE.

Design: In an online experiment, 175 female BC patients were randomly assigned to one of three conditions. In the two experimental groups, patients were informed about the possible occurrence of cognitive problems after chemotherapy with (intervention group) or without (experimental group) reassuring information that ‘there are still patients who score well on memory tests’. In the control group, no reference to chemotherapy-related cognitive problems was made.

Main outcome measures: Main dependent measure was CPR. Four moderating and five mediating processes were examined.

Results: CPR increased with higher levels of stigma consciousness in the two experimental groups, but not in the no-information control group.

Conclusion: Merely informing patients about cognitive side effects may increase their occurrence, especially among individuals vulnerable to patient stereotypes. Adding reassuring information is not sufficient to reduce AIE.     

Connect within to connect outside: effect of salespeople's political skill on relationship performance

Scholars have recently explored the effects of salespeople's intraorganizational relationships on salespeople's job-related outcomes. Grounded in social influence theory, we explore the effects of salespeople's intraorganizational skills on salesperson relationship performance. We empirically tested the proposed relationships using the data from a non-Western sales force working with an organization in an emerging economy. The results indicate that salespeople's political skill positively contributes to salespeople's identification with the organization and to creative performance, while strikingly, we also find that salesperson task adaptivity weakens these effects. Moreover, salespeople's identification and creative performance are positively related to customer satisfaction. These findings demonstrate that salespeople's intraorganizational relationships play a key role in enhancing customer satisfaction. In light of these results, we explore implications for marketers and academics and conclude by suggesting directions for further research.     

Accelerated lamellar disintegration in eutectoid steel

The fastest kinetics of lamellar disintegration (predicted duration of 44 min) in AISI 1080 steel is obtained with a novel approach of incomplete austenitisation-based cyclic heat treatment involving forced air cooling with an air flow rate of 8.7 m³ h^?1. A physical model for process kinetics is proposed that involves lamellar fragmentation, lamellar thickening, divorced eutectoid growth and generation of new lamellar faults in remaining cementite lamellae in each cycle. Lamellar fragmentation is accentuated with faster rate of cooling through generation of more intense lamellar faults; but divorced eutectoid growth is ceased. Accordingly, as compared to still air cooling, much faster kinetics of lamellar disintegration is obtained by forced air cooling together with the generation of much smaller submicroscopic cementite particles (containing more proportion of plate-shaped non-spheroids) in divorced eutectoid region.     

Neurobiologie der Bipolar-1-Störung

Der Psychiater Dr. Alexander Neumeister betreibt an der Universit?t Yale Grundlagenforschung zur Beschreibung der Neurobiologie psychiatrischer Erkrankungen. Dabei gilt sein besonderes Augenmerk affektiven Erkrankungen, Angstst?rungen und der posttraumatischen Belastungsst?rung. Ein weiterer Schwerpunkt seiner Forschungst?tigkeit ist die Psychopharmakologie. Um neurochemische Prozesse im Gehirn zu beschreiben bedient sich Neumeister verschiedener bildgebender Verfahren, vor allem der Positronen-Emissions-To-mographie.     

D-N认知评估系统在AD/HD儿童认知评估中的应用

研究采用基于PASS理论建构的D-N认知评估系统(CAS)作为主要评估工具, 以临床推介的18名AD/HD儿童和18名在性别、年龄及智力水平与临床样本相匹配的正常儿童为被试, 对其PASS认知过程特征开展比较研究, 探查临床组儿童潜在的认知过程异常, 研究结果表明:(1)临床AD/HD儿童在CAS总量表分上显著低于正常对照组儿童;(2)临床AD/HD儿童与正常对照组儿童在计划和注意过程分数上存在显著差异, 且临床AD/HD儿童的计划和注意分量表分数可很好地预测其在DSM-IV上的注意涣散评估分数;(3)临床AD/HD组儿童与正常对照组儿童在同时性加工和继时性加工水平上则没有显著差异。     

Using movement and intentions to understand human activity

During perception, people segment continuous activity into discrete events. They do so in part by monitoring changes in features of an ongoing activity. Characterizing these features is important for theories of event perception and may be helpful for designing information systems. The three experiments reported here asked whether the body movements of an actor predict when viewers will perceive event boundaries. Body movements were recorded using a magnetic motion tracking system and compared with viewers’ segmentation of his activity into events. Changes in movement features were strongly associated with segmentation. This was more true for fine-grained than for coarse-grained boundaries, and was strengthened when the stimulus displays were reduced from live-action movies to simplified animations. These results suggest that movement variables play an important role in the process of segmenting activity into meaningful events, and that the influence of movement on segmentation depends on the availability of other information sources.     

Spirituality in Disability and Illness

Spirituality appears with increasing frequency in the research literature, and a paradigm involving mind-body-spirit interaction is emerging. The relationship of spirituality to disability and illness is at the center of a growing body of knowledge. A comprehensive literature review supported spirituality as coping method among individuals experiencing a variety of illnesses including hypertension, pulmonary disease, diabetes, chronic renal failure, surgery, rheumatoid arthritis, multiple sclerosis, HIV/AIDS, polio and addictive illnesses. Additionally, spirituality is a resource when dealing with critical illness as well as terminal illness and end of life issues, and it is utilized by both patients, and family members. Discussion of research findings, implications for health care practice and future research is also presented.     

Common and Specific Dimensions of Self-Reported Anxiety and Depression in Adolescent Outpatients

To investigate the common and specific dimensions of anxiety and depression in adolescents, the Beck Anxiety Inventory (BAI; Beck, A. T., & Steer, R. A. Manual for the Beck Anxiety Inventory. San Antonio, TX: Psychological Corporation 1993a) and Beck Depression Inventory-II (BDI-II; Beck, A. T., Steer, R. A., & Brown, G. K. Manual for Beck Depression Inventory (2nd Ed.). San Antonio, TX: Psychological Corporation 1996) were administered to 840 adolescent (13–17 years old) outpatients who were diagnosed with various types of psychiatric disorders. A Schmid-Leiman transformation was used with the iterated-principal-factor pattern matrix of the BAI and the BDI-II loadings. The amounts of orthogonalized common variance that were explained by the one second-order (56%), one first-order depression (22%), and two first-order anxiety (22%) dimensions were comparable to those previously reported for adult psychiatric outpatients. The results were discussed as supporting the construct of negative affectivity that is proposed in L. A. Clark and Watson’s (1991) tripartite model of anxiety and depression.

The relationship between biological and psychosocial risk factors and resting‐state functional connectivity in 2‐month‐old Bangladeshi infants: A feasibility and pilot study

Childhood poverty has been associated with structural and functional alterations in the developing brain. However, poverty does not alter brain development directly, but acts through associated biological or psychosocial risk factors (e.g. malnutrition, family conflict). Yet few studies have investigated risk factors in the context of infant neurodevelopment, and none have done so in low‐resource settings such as Bangladesh, where children are exposed to multiple, severe biological and psychosocial hazards. In this feasibility and pilot study, usable resting‐state fMRI data were acquired in infants from extremely poor (n = 16) and (relatively) more affluent (n = 16) families in Dhaka, Bangladesh. Whole‐brain intrinsic functional connectivity (iFC) was estimated using bilateral seeds in the amygdala, where iFC has shown susceptibility to early life stress, and in sensory areas, which have exhibited less susceptibility to early life hazards. Biological and psychosocial risk factors were examined for associations with iFC. Three resting‐state networks were identified in within‐group brain maps: medial temporal/striatal, visual, and auditory networks. Infants from extremely poor families compared with those from more affluent families exhibited greater (i.e. less negative) iFC in precuneus for amygdala seeds; however, no group differences in iFC were observed for sensory area seeds. Height‐for‐age, a proxy for malnutrition/infection, was not associated with amygdala/precuneus iFC, whereas prenatal family conflict was positively correlated. Findings suggest that it is feasible to conduct infant fMRI studies in low‐resource settings. Challenges and practical steps for successful implementations are discussed.