Heart rate, recall, and reaction-time measures of levels of processing

A problem of circularity emerges in any attempt to index depth by retention alone. In the present study, reaction time (RT), and heart-rate response were used to index the three qualitatively distinct levels of physical, phonemic, and semantic processing. An additional objective was to distinguish between the three levels under incidental vs intentional learning conditions. Subjects were 46 male undergraduates who were given 30 trials. A trial consisted of the presentation of an orienting question and an imperative word-stimulus separated by a 6-sec. interval. There were three types of questions in order to induce processing to one of the three target levels. The results indicated that recall as well as heart-rate acceleration distinguished between two (physical vs phonemic and semantic) rather than three levels of processing in the incidental condition. Heart-rate change differentiated between incidental and intentional, the intentional condition showing a smaller change. Semantic and phonemic RTs were faster than physical RT, but there were no differences between semantic and phonemic RTs. Intentional recall was superior to incidental recall. It is suggested that psychophysiological indices can provide independent evidence for 'levels of processing.'     

Medical Education for Social Justice: Paulo Freire Revisited

Although social justice is an integral component of medical professionalism, there is little discussion in medical education about how to teach it to future physicians. Using adult learning theory and the work of Brazilian educator Paulo Freire, medical educators can teach a socially-conscious professionalism through educational content and teaching strategies. Such teaching can model non-hierarchical relationships to learners, which can translate to their clinical interactions with patients. Freirian teaching can additionally foster professionalism in both teachers and learners by ensuring that they are involved citizens in their local, national and international communities.     

Canavan disease: a white matter disorder

Breakdown of oligodendrocyte-neuron interactions in white matter (WM), such as the loss of myelin, results in axonal dysfunction and hence a disruption of information processing between brain regions. The major feature of leukodystrophies is the lack of proper myelin formation during early development or the onset of myelin loss late in life. These early childhood WM diseases are described as hypomyelination or dysmyelination arising from a primary block in normal myelin synthesis because of a genetic mutation expressed in oligodendrocytes, or failure in myelination secondary to neuronal or astroglial dysfunctions (van der Knaap 2001 Dev. Med. Child Neurol. 43:705-712). Here, we describe the pathophysiological parameters of Canavan disease (CD), caused by genetic mutations of the aspartoacylase (ASPA) gene, a metabolic enzyme restricted in the central nervous system (CNS) to oligodendrocytes. CD presents pathophysiological dysfunctions similar to diseases caused by myelin gene mutations, such as Pelizaeus-Merzbacher disease (PMD) and several animal models, such as myelin deficient rat (md), jimpy (jp), shiverer (sh), and quaking (qk viable) mutant mice. These single gene mutations have pleiotropic effects, whereby the alteration of one myelin gene expression disrupts functional expression of other oligodendrocyte genes with an outcome of hypomyelination/dysmyelination. Among all of the known leukodystrophies, CD is the first disorder, which was approved and tested for the adeno-associated virus vector (AAV)-ASPA gene therapy (Leone et al. 2000 Ann. Neurol. 48:27-38; Janson et al. 2001 Trends Neurosci. 24:706-712) without much success following the first two attempts. ASPA gene delivery attempts in animal models have shown a lowering of N-acetyl L-aspartate and a change in motor functions, while sponginess of the WM, a characteristic of CD remained unchanged (Matalon et al. 2003 Mol. Ther. 7 (5, Part 1):580-587; McPhee et al. 2005 Brain Res. Mol. Brain Res. 135:112-121) even with better viral serotype and delivery of the gene during early phase of development (Klugmann et al. 2005 Mol. Ther. 11:745-753). While different approaches are being sought for the success of gene therapy, there are pivotal developmental questions to address regarding the specific regions of the CNS and cell lineages that become the target for the onset and progression of CD symptoms from early to late stages of development.     

Fragment difficulty in priming on word-completion tests

Word-fragment completion is a frequently used test in implicit memory research. In this test priming is the relevant variable. Priming is obtained by subtracting the proportion of nonstudied word fragments correctly completed (called "completion difficulty baseline") from the studied word fragments correctly completed. Since completion difficulty can spuriously vary greatly between experimental conditions, its effect on magnitude of priming is studied. Normative frequency of occurrence of target words was considered because their influence over performance is known. In an experiment using a word-fragment completion test, participants' completion of fragments at three levels of completion difficulty and two levels of frequency was tested. Analysis showed that completion difficulty had a significant effect on global priming. The priming magnitude was higher for Difficult and Moderately Difficult fragments than for Easy ones. An interaction between fragment difficulty and normative word frequency was observed. When the fragments were easy to complete, the expected effect of higher priming for low-frequency words than for high-frequency words was not observed.     

“The interviewer is a machine!” Investigating the effects of conventional and technology-mediated interview methods on interviewee reactions and behavior

Despite the growing number of organizations interested in the use of asynchronous video interviews (AVIs), little is known about its impact on interviewee reactions and behavior. We randomly assigned participants (N = 299) from two different countries (Switzerland and India) to a face-to-face interview, an avatar-based video interview (with an avatar as a virtual recruiter), or a text-based video interview (with written questions) and collected data on a set of self-rated and observer-rated criteria. Overall, we found that whereas participants reported more negative reactions towards the two asynchronous interviews, observer ratings revealed similar performance across the three interviews and lower stress levels in the two AVIs. These findings suggest that despite technology-mediated interview methods still not being well-accepted, interviewees are not at a disadvantage when these methods are used in terms of how well interviewees perform and how stressed they appear to external observers. Implications are discussed.     

The perceived vulnerability to disease scale: Cross-cultural measurement invariance and associations with fear of COVID-19 across 16 countries

Using cross-sectional data from N = 4274 young adults across 16 countries during the COVID-19 pandemic, we examined the cross-cultural measurement invariance of the perceived vulnerability to disease (PVD) scale and tested the hypothesis that the association between PVD and fear of COVID-19 is stronger under high disease threat [that is, absence of COVID-19 vaccination, living in a country with lower Human Development Index (HDI) or higher COVID-19 mortality]. Results supported a bi-factor Exploratory Structural Equation Modeling model where items loaded on a global PVD factor, and on the sub-factors of Perceived Infectability and Germ Aversion. However, cross-national invariance could only be obtained on the configural level with a reduced version of the PVD scale (PVD-r), suggesting that the concept of PVD may vary across nations. Moreover, higher PVD-r was consistently associated with greater fear of COVID-19 across all levels of disease threat, but this association was especially pronounced among individuals with a COVID-19 vaccine, and in contexts where COVID-19 mortality was high. The present research brought clarity into the dimensionality of the PVD measure, discussed its suitability and limitations for cross-cultural research, and highlighted the pandemic-related conditions under which higher PVD is most likely to go along with psychologically maladaptive outcomes, such as fear of COVID-19.     

Use of the Beck Depression Inventory-II with Adolescent Psychiatric Outpatients

To provide information on the use of the Beck Depression Inventory-II (BDI-II) with adolescents, the BDI-II was administered to 105 male and 105 female outpatients between 12 and 18 years old who were seeking psychiatric treatment. The internal consistency of the BDI-II was high (coefficient = .92). The mean BDI-II total score of the girls was approximately 5 points higher than that of the boys (p < .001), and age (years) was positively correlated with the BDI-II total scores (r = .18, p < .01). An iterated principal-factor analysis identified three factors, but only the Cognitive and Somatic-Affective factors were generalizable.     

Gender Roles and Cultural Continuity in the Asian Indian Immigrant Community in the U.S.

Ethnic identity is a part of positive self-concept that consciously anchors an individual to a particular ethnic group. Central to this identity is a sense of belonging, as well as a commitment to the group's values, beliefs, behaviors, conventions, and customs. This study focuses on the Asian Indian community in the U.S. to investigate their concerns with the continuity of ethnic identity via maintenance of traditional culture. Intergenerational synchrony in two specific values, attitudes toward women and dating, were examined as indicators of successful transmission of culture and identity. Forty-sixeducated, middle class Indian immigrant families, the majority of whom were foreign born and Hindus,participated in this study by responding to three questionnaires: Attitude Toward Women Scale, Dating Scale, and IPAT Anxiety Scale. Although the results show a strong similarity between parents and children on target attitudes, distinct intergenerational and gender asymmetries emerged. The conscious attempt to preserve certain critical attitudes, values, and behaviors characteristic of the group was labeled “judicious biculturalism,” an expression of active involvement on the immigrants' part to control the course of their own acculturation. The study has implications for women's status within the Asian Indian community.     

Conceptualizing Attachment Trauma: Exploring Emotional Vulnerabilities among Disaster Affected Children of Gujarat

This study compares attachment trauma and psychological adjustment of child survivors of an earthquake and social violence in Gujarat (n = 127). In particular it explores attachment style/s associated with the two disaster traumas and tries to explicate, what these tell us about the particular vagaries of trauma. Results show larger number of insecurely attached children in the disaster trauma sample and the dismissing attachment style dominates particularly in the earthquake sample whereas in the riots sample one can see a presence of what can be termed as a ‘mixed attachment’ style-vacillation between dismissing and preoccupied states of mind. The implications of these findings for a conceptualization of attachment trauma are discussed in details.