Exposure to novelty enhances retrieval of very remote memory in rats

Rats were trained in a one-trial step-down inhibitory avoidance task at the age of 3 months and tested for retention 1 day later, or 3, 6, 9, 12, 15, and 19 months later, i.e., when the animals were 3, 6, 9, 12, 15, 18, or 22 months of age. Retrieval performance declined with time and was undetectable in the last two age groups. Exposure to an unrelated novel environment (a square box lined with black plastic) 1 h before retention testing enhanced retrieval at all ages, regardless of the decline in the level of test session performance. The effect cannot be explained by an anxiogenic effect of the novelty box, or by an influence of novelty on locomotion or exploration, or by a nonspecific influence of exposure to novelty on step-down latency in the inhibitory avoidance apparatus.     

The NK3 receptor agonist senktide ameliorates scopolamine-induced deficits in memory for object, place and temporal order

Senktide, a potent neurokinin-3 receptor (NK₃-R) agonist, increases acetylcholine (ACh) release in the striatum, the prefrontal cortex (Schäble et al., 2011), the amygdala and hippocampus, presumably via postsynaptic mechanisms. A promnestic action of NK₃-R agonists has been described in a variety of learning/memory tasks. The memory-enhancing effects of NK₃-R agonists and their activating influence on ACh suggest a possible role of the NK₃-R in learning and memory via cholinergic modulation. Deterioration of the cholinergic system in the basal forebrain has been associated with learning and memory deficits and cholinergic agents have promnestic effects in a variety of learning paradigms. The anticholinergic drug, scopolamine, a muscarinic ACh receptor antagonist, incurs deficits in a variety of learning tasks and provides a useful tool to investigate the role of the cholinergic systems in mechanisms underlying learning and memory. The aim of this study was to ascertain the effect of the NK₃-R agonist, senktide, in the scopolamine-induced deficit model. We hypothesized that senktide treatment would attenuate scopolamine-induced (subcutaneous – s.c. 0.75 mg/kg) memory impairment in three novelty preference paradigms based on spontaneous object exploration: namely object recognition, object–place recognition and object recognition for temporal order. Administration of senktide reversed the scopolamine-induced memory deficits by re-establishing object recognition (s.c. 0.2 mg/kg), object–place recognition (0.2 and 0.4 mg/kg), as well as object recognition for temporal order (0.4 mg/kg) in adult Wistar rats. These results indicate memory enhancing effects of senktide in animals subjected to scopolamine-induced memory impairments and indicate that the promnestic action of NK₃-R agonists is mediated by muscarinic cholinergic mechanisms.     

Cognitive and Value Correlates of Health-Related Behavior in Brazilian Middle-class Women

The prevalence of several health-related behaviors was studied in a random sample of 294 Brazilian middle-class women between 25 and 45 years of age. The interrelationships among these behaviors confirmed previous findings in North America and provided the basis for the computation of a composite index of health behavior. The sociodemographic, cognitive, and value correlates of scores on the Health Behavior Index (HBI) were investigated using regression analysis. Women who behave in favor of good health were mothers of more children, had a definition of health as higher level functioning and self-realization, believed that care outweighs chance as a determinant of health, and valued inner harmony as opposed to comfort and independence. These findings verified most aspects of Pender's health promotion model (Pender, Walker, Sechrist, & Stromberg, 1990).     

Symmetry Evaluation by Comparing Acquisition of Conditional Relations in Successive (Go/No-Go) Matching-to-Sample Training

The Psychological Record - The successive matching-to-sample (go/no-go) procedure has been shown to be an effective procedure for reducing stimulus-control digressions in conditional-relation...     

Family Cultures in The Context of Migration and Ageing

Intergenerational family relations are embedded in family cultures which influence how families regulate their relations over the whole life span with regard to key issues, such as autonomy and relatedness, or support exchange and reciprocity, and which may vary inter- and intraculturally. Migrant families undoubtedly face a special situation as values and expectations from the culture of origin and from the host cultural context might differ. Not much is known yet about how migrant families adapt their family cultures to the host cultural context. The present article will focus on aspects of intergenerational family regulation by taking into account family cultures of migrant compared to non-migrant families in a life span perspective. We will illustrate our theoretical outline by presenting first results from the IRMA-study comparing Luxembourgish and Portuguese immigrant families living in Luxembourg. We focus on issues of family cohesion, enmeshment and normative expectations regarding adult children’s support for their ageing parents, by drawing both on quantitative questionnaire as well as qualitative interview data. Implications for the experience of ambivalence and conflicts as well as well-being of family members from both generations will be discussed.     

Perceived control and anxiety in Portuguese children

The central role of perceived control in the development of anxiety disorders is proposed by several theoretical models. The main objective of the present study was to examine the relation between perceived control and anxiety in Portuguese school-age children. To accomplish this objective we developed the Portuguese short form of the Anxiety Control Questionnaire for Children (ACQ-C, Weems, 2005; Pereira & Barros, 2010), whose psychometric studies are presented. The sample comprised 238 children, aged 8 to 15 years, from the general population attending Portuguese schools. Children completed measures of perceived control (ACQ-C) and their anxiety (Screen for Child Anxiety Related Emotional Disorders--Revised, SCARED-R). The psychometric studies indicate good psychometric characteristics of the Portuguese ACQ-C short form, in particular a high internal consistency (a = .85) and an adequate temporal stability (r = .60, p = .002). Results show a significant negative association between perceived control and anxiety symptomatology, providing partial support for models that assign a central role to control beliefs in explaining the development of anxiety disorders. These results also suggest the importance of considering the perception of control as a prime target for preventive actions and intervention aimed at reducing anxiety in school aged children.