Extremely Preterm Birth Outcome: A Review of Four Decades of Cognitive Research

Premature birth incidence and survival rates are increasing steadily due to advances in obstetric and neonatal intensive care. Those born at the limits of viability are highly at-risk of adverse neurocognitive function over their lifespan, leading to current controversy regarding aggressive resuscitation efforts for these extremely preterm children. However, data from earlier generation cohorts who were born in substantially different eras of neonatal intensive care cannot be relied on to predict outcome of today’s newborn. Our review by the crucial variable of birth cohort year shows a changing developmental trajectory in which today’s extremely preterm survivor is likely to have fewer severe medical complications, better neurological outcomes, and fewer adverse cognitive late effects. Such data further underscore the importance of concurrently considering medical, familial, socioenvironmental, and neurobiological factors in combination with individual neonatal intensive care center protocols when studying outcomes of the preterm child. This complex, interrelated range of factors directly affects the immature, rapidly developing premature brain. However, ongoing surveillance to detect subsequent delay or impairment and to apply interventional strategies early in the developmental course holds promise for further enhancement of functional outcome.     

Some variables affecting dentists' assessment of patients' distress

Dental students estimated the pain distress and discomfort of their patients after patients received a Class II restoration (simple filing). Dentist's estimates of patient pain accounted for 36% of the variance in patient self-report responses. Dentist accuracy was significantly lower, however, for estimates of anxiety and distress. Dentist accuracy was unaffected by patient's degree of self-monitoring. There was a tendency for female dentists to demonstrate greater accuracy than male dentists, but this effect was nonsignificant. In addition, dentists' accuracy in assessing overall patient discomfort was significantly lower in that segment of the treatment procedure that was most stressful for the dentists. This article discusses theoretical explanations for this latter effect.     

Reference Points and Omission Bias

Subjects were asked to evaluate the choice of options leading to known outcomes, or to say how they would feel about a chance outcome, in hypothetical decisions. We independently manipulated the value of the status quo and the assignment of the better or worse outcome to an act or an omission. Acts leading to the worse outcome were always considered worse than omissions leading to the worse outcome. This act-omission difference was reduced or reversed for the better outcome. Most experiments showed an overall bias toward omissions (combining better and worse). Little evidence was found for greater omission bias for losses relative to the status quo than for gains. A bias toward maintaining the status quo itself was found, however, independently of omission bias. Most of the results can be explained by norm theory and by loss aversion, but other possible accounts are inconsistent with the results.     

Effects of negative ions on interpersonal attraction: evidence for intensification

In Study 1, female subjects received information suggesting either that a stranger (a female accomplice) shared their attitudes and evaluated them positively or that a stranger did not share their attitudes and evaluated them negatively. These procedures took place in the presence of a low (ambient) or high level of negative ions. On the basis of previous research, it was predicted that a high level of negative ions would intensify subjects' reactions to the stranger, thus enhancing their evaluations of her when she seemed to share their attitudes and to like them, but reducing these evaluations when she did not share their attitudes and disliked them. Results offered support for these predictions. In Study 2, female subjects performed two tasks (letter and digit copying) in the presence of a low or high concentration of negative ions. Their blood pressure and pulse were measured at several points during the experiment. Results indicated that on various trials both systolic and diastolic blood pressure were higher in the high-ions than in the low-ions condition. In addition, subjects reported higher levels of subjective arousal and made significantly more errors on the letter-copying task in the presence of a high concentration of negative ions. Together, the results of these studies were interpreted as offering support for the view that high concentrations of negative ions can increase both physiological and psychological (subjective) arousal.     

The development of implicit intergroup cognition

Challenging the view that implicit social cognition emerges from protracted social learning, research now suggests that intergroup preferences are present at adultlike levels in early childhood. Specifically, the pattern of developmental emergence of implicit attitudes is characterized by (i) rapidly emerging implicit preferences for ingroups and dominant groups and (ii) stability of these preferences across development. Together these findings demonstrate that implicit intergroup preferences follow a developmental course distinct from explicit intergroup preferences. In addition these results cast doubt on 'slow-learning' models of implicit social cognition according to which children should converge on adult forms of social cognition only as statistical regularities are internalized over a lengthy period of development.     

The Ontogenesis of Language Impairment in Autism: A Neuropsychological Perspective

Autistic Disorder (AD) is a phenotypically heterogeneous condition characterized by impairments in social interaction, communication, and the presence of repetitive behavior and restricted interests. It is a model syndrome to investigate neural interaction and integration at the nexus of language and social cognition. This paper considers the problems of language acquisition in AD from an evolutionary and ontogenetic context. Following a review of normal language development during the formative years of brain development, we examine what is known about infant linguistic and nonlinguistic precursors of language acquisition in AD and examine how anomalies of several processes relate to language abnormalities manifest by the early elementary school years. Population heterogeneity and practical limitations inherent to the study of children currently limit a comprehensive understanding of the significance of specific neurological abnormalities in relation to observed deficits. However, convergent evidence implicates anomalies of a widely distributed neural network, involving superior temporal sulcus, superior temporal gyrus, supramarginal gyrus, insula, inferior frontal gyrus, hippocampus, amygdala and cerebellum. These anomalies reflect the cumulative effects of genetic, epigenetic and environmental influences. Neuropsychological studies of language in AD provide an important means to define the phenotypic variation resulting from alterations in neural architecture. By mapping broad relationships between key symptoms, neuropsychological impairment and neural substrate, information derived from these studies enable a level of analysis that bridges the gap between the genome and the syndrome. Further study of children during the critical first 2 years of life using behavioral, electrophysiological, and functional neuroimaging methods is essential.