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131.
2-Deoxy-D-galactose, an inhibitor of brain glycoprotein fucosylation, was injected intracranially (10 mumole dose in 10 microliters) into either the left or the right forebrain hemisphere of day-old chicks (Gallus domesticus). Bilateral injection of this dose of 2-deoxy-D-galactose is known to induce amnesia for several learning tasks including one-trial passive avoidance and sickness-induced learning. When a tritiated form of the drug was injected into one forebrain hemisphere only, a significantly large proportion of the dose remained in that hemisphere. Chicks were trained in two different one-trial learning tasks. The first was a passive avoidance task in which the chicks were allowed to peck at a green training stimulus (a small light-emitting diode, LED) coated in the bitter liquid, methylanthranilate, giving rise to a strong disgust response and consequent avoidance of the green stimulus. In the second paradigm the chicks were allowed to peck at a similarly colored dry stimulus but, 30 min later, were injected intraperitoneally with lithium chloride (0.1 ml of 1 M solution), causing a sickness-induced aversion for the green LED. 2-Deoxy-D-galactose caused amnesia for the passive avoidance task when injected before training into the right hemisphere but not the left. However, unilateral injection of the drug before training on the sickness-induced learning task did not cause amnesia. The results indicate that fucosylation of brain glycoproteins is required in the right hemisphere for learning the passive avoidance task but that memory for sickness-induced learning can be retained by either hemisphere. 相似文献
132.
Despite many speculations, there is no well-supported explanation for cycles of fashion in.women's dress and scholars cannot agree whether fashions reflect societal changes. Generalizing from cycles of bodily attractiveness for women, it was hypothesized that dress styles are reflective of reproductive economics. Using data from three studies of dress fashion extending from 1885-1976, the prediction was tested thatshortskirts (signaling sexual accessibility) would be correlated with low sex ratios (indicating limited marital opportunity for women), with increased economic opportunities for women and with marital instability. Predictions for narrowwaists and low necklines (which signal reproductive value) were opposite. These predictions received strong support indicating that dress styles, like standards of bodily attractiveness may be partly determined by marital economics. 相似文献
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134.
Lesion studies show that the intermediate medial hyperstriatum ventrale (IMHV), a forebrain visual association area in chicks, is involved in learning and memory for one-trial passive avoidance and imprinting. We examined the effects of IMHV lesions in a one-trial, nongustatory, sickness-conditioned learning task. This task is similar to passive avoidance and imprinting because all three tasks require the chick to remember visual cues in order to respond correctly. However, sickness-conditioned learning differs from imprinting and passive avoidance because it uses sickness as the aversive stimulus and there is a longer conditioned stimulus-unconditioned stimulus interval (30-min delay compared to seconds). Bilateral IMHV lesions given 24 h before training impaired the ability of the chicks to avoid a bead associated with sickness produced by lithium chloride injection, as did pretraining unilateral left or right IMHV lesions. Post-training IMHV lesions given 1 h after training did not impair avoidance of the test bead in the sickness-conditioned learning task. However, lesioned chicks showed generalized avoidance of all test beads. The pretraining lesion results are similar to those found in imprinting and passive avoidance learning; however, the effects of unilateral IMHV lesions differed. Post-training lesion effects are similar to those found in passive avoidance learning. We propose that both left and right IMHV are necessary for sickness-conditioned learning and that post-training IMHV lesions impair the ability of the chick to learn or remember the association between the color of the bead and the aversive consequences of LiCl injection. 相似文献
135.
The purpose of this study is to analyse the evolution of gender perspective in the context of the Spanish academic Psychology. The last three decades were analysed. In each decade, the study describes the groups and individuals who have contributed to the analysis of gender perspective in Psychology, the sponsoring institutions, and the most frequently used research strategies. Likewise, the study analyses the development of topics and areas in these three decades. The general trend shows that the interpretation of sex/gender has moved away from being considered an individual and internal factor to a more dynamic approach that analyses sex/gender through behavioural practices. 相似文献
136.
Previous classroom studies have shown that the phenomenology of studied facts changes over time. However, pedagogical needs preclude both the study of errors and the separation of the effects that delay and repeated testing have on retention and retrieval experience. We addressed these issues together in an experiment where participants read stories containing correct and misleading information and provided Remember, Just Know, and Familiar judgements on immediate and delayed general knowledge tests. After 2 days, information learned from the stories shifted from Remembered to Just Known, but repeated testing attenuated this shift. Interestingly, similar patterns of retrieval and phenomenology were observed for correct and misleading information with one important difference--the shift over time to Just Knowing was significantly greater for correct than for misleading information. Together, these findings show the roles of information accuracy, delay, and testing in determining both retention and the subjective experience of retrieval. 相似文献
137.
Szmalec A Duyck W Vandierendonck A Mata AB Page MP 《Quarterly journal of experimental psychology (2006)》2009,62(3):435-443
The present study tests the hypothesis that a common ordering mechanism underlies both short-term serial recall of verbal materials and the acquisition of novel long-term lexical representations, using the Hebb repetition effect. In the first experiment, participants recalled visually presented nonsense syllables following a typical Hebb effect learning protocol. Replicating the Hebb repetition effect, we observed improved recall for repeated sequences of syllables. In the second experiment, the same participants performed an auditory lexical decision task, which included nonwords that were constructed from the syllables used in the first experiment. We observed inhibited rejection of nonwords that were composed of the repeated Hebb sequences, compared to nonwords that were built from nonrepeated filler sequences. This suggests that a long-term phonological lexical representation developed during Hebb learning. Accordingly, the relation between immediate serial recall and word learning is made explicit by arguing that the Hebb repetition effect is a laboratory analogue of naturalistic vocabulary acquisition. 相似文献
138.
Almonte AG Hamill CE Chhatwal JP Wingo TS Barber JA Lyuboslavsky PN David Sweatt J Ressler KJ White DA Traynelis SF 《Neurobiology of learning and memory》2007,88(3):295-304
The roles of serine proteases and protease activated receptors have been extensively studied in coagulation, wound healing, inflammation, and neurodegeneration. More recently, serine proteases have been suggested to influence synaptic plasticity. In this context, we examined the role of protease activated receptor 1 (PAR1), which is activated following proteolytic cleavage by thrombin and plasmin, in emotionally motivated learning. We were particularly interested in PAR1 because its activation enhances the function of NMDA receptors, which are required for some forms of synaptic plasticity. We examined several baseline behavioral measures, including locomotor activity, expression of anxiety-like behavior, motor task acquisition, nociceptive responses, and startle responses in C57Bl/6 mice in which the PAR1 receptor has been genetically deleted. In addition, we evaluated learning and memory in these mice using two memory tasks, passive avoidance and cued fear-conditioning. Whereas locomotion, pain response, startle, and measures of baseline anxiety were largely unaffected by PAR1 removal, PAR1-/- animals showed significant deficits in a passive avoidance task and in cued fear conditioning. These data suggest that PAR1 may play an important role in emotionally motivated learning. 相似文献
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140.
Michael D. Barber 《Human Studies》2017,40(4):565-588
This essay describes some of the basic pragmatic tendencies at work in the world of working and then shows how the finite provinces of meaning of theoretical contemplation and literature act against those pragmatic tendencies. This analysis prepares the way to see how the religious province of meaning in a similar but also distinctive way acts back against these pragmatic tendencies. These three finite provinces of meaning make it possible to see the world from another center of orientation than that of the ego agens and its proclivity to bring transcendences within reach, thereby freeing oneself to a degree from the fundamental anxiety and revealing the uniqueness of oneself and others, who are no longer subjected to working’s pragmatic imperatives. 相似文献