Evidence of Non-Linear Associations between Frustration-Related Prefrontal Cortex Activation and the Normal:Abnormal Spectrum of Irritability in Young Children

Burgeoning interest in early childhood irritability has recently turned toward neuroimaging techniques to better understand normal versus abnormal irritability using dimensional methods. Current accounts largely assume a linear relationship between poor frustration management, an expression of irritability, and its underlying neural circuitry. However, the relationship between these constructs may not be linear (i.e., operate differently at varying points across the irritability spectrum), with implications for how early atypical irritability is identified and treated. Our goal was to examine how the association between frustration-related lateral prefrontal cortex (LPFC) activation and irritability differs across the dimensional spectrum of irritability by testing for non-linear associations. Children (N = 92; ages 3–7) ranging from virtually no irritability to the upper end of the clinical range completed a frustration induction task while we recorded LPFC hemoglobin levels using fNIRS. Children self-rated their emotions during the task and parents rated their child’s level of irritability. Whereas a linear model showed no relationship between frustration-related LPFC activation and irritability, a quadratic model revealed frustration-related LPFC activation increased as parent-reported irritability scores increased within the normative range of irritability but decreased with increasing irritability in the severe range, with an apex at the 91st percentile. Complementarily, we found children’s self-ratings of emotion during frustration related to concurrent LPFC activation as an inverted U function, such that children who reported mild distress had greater activation than peers reporting no or high distress. Results suggest children with relatively higher irritability who are unimpaired may possess well-developed LPFC support, a mechanism that drops out in the severe end of the irritability dimension. Findings suggest novel avenues for understanding the heterogeneity of early irritability and its clinical sequelae.     

Positive factors associated with quality of life among Chinese patients with renal carcinoma: a cross-sectional study

Quality of life and positive psychological variables has become a focus of concern in patients with renal carcinoma. However, the integrative effects of positive psychological variables on the illness have seldom been reported. The aims of this study were to evaluate the quality of life and the integrative effects of hope, resilience and optimism on the quality of life among Chinese renal carcinoma patients. A cross-sectional study was conducted at the First Hospital of China Medical University. 284 participants completed questionnaires consisting of demographic and clinical characteristics, EORTC QLQ-C30, Adult Hope Scale, Resilience Scale-14 and Life Orientation Scale-Revised from July 2013 to July 2014. Pearson’s correlation and hierarchical regression analyses were performed to explore the effects of related factors. Hope, resilience and optimism were significantly associated with quality of life. Hierarchical regression analyses indicated that hope, resilience and optimism as a whole accounted for 9.8, 24.4 and 21.9% of the variance in the global health status, functioning status and symptom status, respectively. The low level of quality of life for Chinese renal carcinoma patients should receive more attention from Chinese medical institutions. Psychological interventions to increase hope, resilience and optimism may be essential to enhancing the quality of life of Chinese cancer patients.     

Rheumatoid arthritis is associated with negatively variable impacts on domains of female sexual function: evidence from a systematic review and meta-analysis

To systematically review the literature to identify the impact of rheumatoid arthritis (RA) on specific female sexual function domains. A meta-analysis was performed and the related literature were searched in MEDLINE, EMBASE, Cochrane Library, CNKI, CBM and Web of Science databases, and in reference lists of articles and systematic reviews. Score of the Female Sexual Function Index (FSFI) was used as the outcome measurement, and mean differences (MD) with 95% confidence intervals (CI) were calculated. Five studies were included, including 346 women with RA and 237 healthy female controls. Each domain of the FSFI score: lubrication (MD, ?2.48; 95% CI, ?3.69, ?1.28), orgasm-1.71 (?2.09, ?1.33), sexual desire-1.27 (?1.59, ?0.95), satisfaction-1.67 (?2.18, ?1.16), arousal-1.83 (?2.85, ?0.82), pain-1.57 (?2.43, ?0.70) and the total score ?8.84 (?11.88, ?5.79) were lower in RA women than healthy controls. Furthermore, lubrication dimension was most severely affected especially. This meta-analysis showed that female RA patients scored lower in each dimension of FSFI, mostly in the lubrication domain. It demonstrated that targeted interventions should be done to improve their sexual function. Future well-designed researches with larger sample sizes are necessary to evaluate the potential risk factors which determine female sexual dysfunction.     

Posttraumatic growth and parental bonding in young adults of parents with physical disabilites: testing mediation model of resilience

Positive parent-child relationships are associated with positive youth development, but little is known about the relationships between parental bonding, resilience, and posttraumatic growth, which is positive change resulting from the struggle with trauma. This study examined a mediation model among 119 female young adults with disabled parents. The model included resilience as a mediator of the relationship between the paternal Care and posttraumatic growth. The results revealed that resilience did mediate the relationship between the paternal Care and posttraumatic growth. The findings indicate that paternal Care helps to foster female young adults’ resilience, which benefits their growth after suffering adversities.     

Developmental Psychology Research Based on Educational Practice in China

As a developmental psychologist who has conducted studies in educational practice for about thirty years. A series of developmental psychology studies rooted in Chinese culture were performed, and the findings led us to focus on students’ potential in growth, developmental fullness and educational ecosystem. This article mainly talked about three aspects: the viewpoints about the nature of psychological development formed in the context of school; promoting students’ development by continually constructing cultural ecosystem; the characteristics of researches by taking the perspective of cultural ecology and discoveries about deficiency in basic abilities. All of these were based on educational objectives and conducted in educational practice, so they were integrative and dynamic transformation. In educational intervention, aesthetic potential was also found. The relation between aesthetic potential and full development was put forward.     

Beyond the leftward limit of the perceptual span: Parafoveal processing to the left of fixation in Chinese reading

During reading, Chinese readers have been found to obtain useful visual information from one character to the left to three characters to the right of fixation. The perceptual span is asymmetrical, and its leftward extent seems to be limited compared with the rightward extent. We conducted an experiment to investigate whether Chinese readers could process written information beyond the leftward extent of the perceptual span. We did this by using a variation of the gaze-contingent display change paradigm (Rayner, Cognitive Psychology, 81, 65–81, 1975) in order to manipulate the parafoveal “postview” that was available to the left of where readers were fixating. Each sentence contained an invisible boundary. Once the readers’ eyes crossed the boundary, all of the characters to the left of the boundary except for one, two, or three characters directly to the left of the boundary were replaced with visually similar characters. The change lasted for only one single fixation, resulting in four different “postview” conditions including a control condition (n ? 1, n ? 2, n ? 3, control). The results showed that, compared with the control condition, there were more regressions to the display change area immediately after readers’ eyes crossed the boundary in the n ? 1, n ? 2, and n ? 3 conditions, demonstrating that readers can acquire information from the three characters to the left of fixation at least.     

扩大内需:基于“母市场效应”的理论评述

本文主要对母市场效应理论进行文献评述。描述了Krugman关于母市场效应理论的最初模型,并介绍了对母市场效应的理论拓展和实证检验,文章最后提出了在中国出口市场面临一定变化和强调扩大内需条件下对中国制造业出口的母市场效应进行实证检验的一些设想。     

废除不平等条约后国民政府的教会租地政策

1943年起,中国政府先后与英美等国签订平等新约,废除不平等条约。基督教在华租买土地失去了旧有的条约依据。中国政府在1943—1945年间结合新旧条约的规定,采取了一系列的暂时应对之策。1946年起,国民政府先后颁布《过去外人在华地权清理办法三项》、《各地方政府办理外人地权案件应注意事项》重新规范了基督教在华租地权。这些政策在一定程度上起到了应有的作用,但是限于特殊的现实,它未能从根本上解决基督教在华租地的问题。     

晚期癌症患者静脉管理的重要性

恶性肿瘤作为我国的常见病、多发病,其死亡率高居首位.手术、化疗和放疗成为现代医疗对于癌症的常见治疗手段.中晚期癌症患者作为癌症临床诊疗对象的主体,常伴有各种慢性疾病或营养不良.从而,化疗、中药辅助巩固治疗及营养支持治疗成为中晚期癌症患者临床治疗过程中的主体.治疗方法决定给药途径,静脉输液成为了中晚期癌症患者治疗肿瘤的主要手段之一.然而中晚期肿瘤患者静脉穿刺难度大,易发生输液渗漏和静脉炎等特点,以及各种高浓度强刺激性药物和输液器材对静脉血管造成的损伤,都对中晚期癌症患者的疾病治疗产生了不同程度的不利影响.对于中晚期癌症患者来说,静脉保护的程度直接关系到患者疾病治疗的进程及享受到的生命质量.因此,医护人员应对静脉输液致血管损害的相关因素予以高度重视及时采取血管维护的对策,同时加强对输液患者进行静脉维护知识的宣教,促使其树立静脉护理的意识和能力.     

佛法与国法:规范合力与意义勾连——佛教与传统法律研究述评

佛教与传统法律的关系在学界一直受到关注,从宏观到微观的专题研究也取得了越来越丰富的成果。这些成果对二者的关系从静态描述到动态发展阐述,从单向性影响到双向性互动,从大传统到小传统,从历史现象到现实意义,各个领域都有了一定的积累。在进一步的研究中,规范分析方法的运用、民间文本的重视和司法领域的关注,是取得新突破的有效途径。