小剂量吗啡对大鼠活动性的影响

腹腔注射不同剂量吗啡,观察各组大鼠在给药后不同时间的活动性（ｌｏｃｏｍｏｔｏｒａｃｔｉｖｉｔｙ,ＬＡ）,连续给药８天,每天给药后９５ｍｉｎ内,每间隔１５ｍｉｎ,记录大鼠５ｍｉｎ内在限定空间中所走格数。结果表明：随吗啡给药剂量或次数增加,ＬＡ呈升高趋势;使大鼠ＬＡ明显兴夯的适宜低剂量为４ｍｇ／ｋｇ／ｄａｙ,该剂量下每天药后１５－２０ｍｉｎＬＡ为峰值,而且此时段ＬＡ逐日升高,至第８日出现下降趋势,此毕     

相信"过年吃药不吉利"险些丧命

有一些人出于不良的目的,宣称:患病不吃药,烧香念佛好。当然,若是邪教的目的就更险恶了!曾发生过这么一件事情:辽宁省盘锦地区,在民间传出“过年吃药不吉利”的谣言,并称,吃一次药,就一年到头药离不了口,折腾一年,一年在苦海中煎熬。这种显而易见的谣言竟还有人相信,在短短的两天时间内,一家医院就先后抢救了11位心     

医患风险沟通：角色与信息匹配的视角

医患沟通失真常引发高误诊率、医患冲突。现有风险具体观和抽象观各自提出风险沟通模型,但存在诸多矛盾或不一致。通过引入角色与信息匹配视角,从建构水平理论提出事件体验(事件吸引力)和概率体验(概率敏感性)解释,有助于调和矛盾并提出建议：为医生匹配抽象风险信息、患者匹配具体风险信息,能减少沟通失真,提高风险沟通质量。未来需进一步深究个体差异对匹配效应的影响、探索匹配效应的生态效度、开发科学有效的沟通模式。     

汉字亚词汇部件语音加工的P200效应

亚词汇加工是词汇识别研究中的一个重要领域,本研究考察了早期ERP成分P200如何受到汉字亚词汇部件语音信息的影响。在ERP实验中,被试对顺序呈现的启动字和目标字对进行语义判断。实验中“启动字-目标字”字对共享一个共同的可发音或不可发音的部件（如“吹-砍”、“扬-场”）。对目标字的P200效应分析显示：与部件不发音的目标字相比,部件可发音的目标字所诱发的P200显著增强。这种增强的ERP效应表明P200对汉字识别中亚词汇部件的语音加工非常敏感,其效应变化受到亚词汇语音的单独调节,同时也表明在汉字识别的早期阶段亚词汇部件语音信息就已被激活并在汉字加工中起重要作用。     

Foot Motion Character During Forward and Backward Walking With Shoes and Barefoot

Abstract

Backward walking (BW) has been extensively used in athletic training and orthopedic rehabilitation as it may have value for enhancing balance. This study identified the differences in foot intersegment kinematics (forward walking (FW) vs. time-reversed BW) and plantar pressure parameters of 16 healthy habitually shod individuals walking FW and BW using flexible shoes (SH) and under barefoot conditions (BF). BW was found to have shorter stride length (SL) and higher stride frequency (SF) under BF conditions compared with SH, which indicates a better BW gait stability under BF conditions. Decreased HX/FF dorsiflexion at HO in BW induces less plantar aponeurosis tension which may inhibit the windlass mechanism compared to FW walking. Increased forefoot relative to hindfoot (FF/HF) pronation and sequentially hindfoot relative to tibia (HF/TB) eversion combined with medially distributed plantar pressure and a higher plantar contact area in the medial side in BW–BF maybe beneficial in maintaining balance. These results indicate that BW training may be more reliable under BF conditions compared to the SH conditions based on greater sensory information feedback from the plantar area resulting in better biomechanical behavior.     

How mindfulness affects benign and malicious envy from the perspective of the mindfulness reperceiving model

At present, mindfulness is a hotspot in psychological research. Mindfulness is an effective tool that enables people to effectively inhibit negative emotions. Previous studies have shown that envy is a typical negative emotion; however, envy can be divided into two completely different types: benign envy and malicious envy. The question then arises, how does mindfulness affect both types of envy? Using a mindfulness reperceiving model, we explored the effect of mindfulness on these two different types of envy and on the mediating mechanism of psychological resilience. To accomplish this, we recruited 676 Chinese undergraduates to complete the Mindful Attention Awareness Scale (MAAS), the Benign and Malicious Envy Scale (BEMAS) and the Connor-Davidson Resilience Scale (CD-RISC). The results we obtained showed that mindfulness and psychological resilience significantly and negatively predicted malicious envy and that psychological resilience played a partially mediating role in the relationship. In addition, the results showed that there was no significant effect between mindfulness and benign envy; however, psychological resilience can significantly and positively predict benign envy and played a completely mediating role between mindfulness and benign envy. These results effectively extend theories based on the mindfulness reperceiving model while also being important for promoting benign envy and inhibiting malicious envy in terms of improving mindfulness and psychological resilience.     

科学发明情境中问题提出的脑机制再探

以高生态学效度的科学发明问题情境作为实验材料, 采用静息态功能磁共振成像技术, 基于低频振幅(ALFF)和静息态功能连接(RSFC)的分析方法, 探讨创造性科学问题提出的脑机制。结果发现, 在控制了被试性别、年龄后, 提出新颖有效性问题的比率越高, 左内侧前额叶(Left media prefrontal cortex, L-mPFC)和右小脑前叶(Right cerebellum)的ALFF值越高。进一步功能连接分析发现, 提出新颖有效性问题的比率与mPFC和楔叶(Cuneus)之间的功能连接强度呈显著正相关。结果强调mPFC对于科学发明情境中问题提出的重要作用, 且更高比率的新颖有效性问题的提出是通过mPFC与其它脑区的协同联结来实现的。     

中小学生正念注意觉知与心理健康：情绪调节和积极重评的跨时间中介作用

本研究探讨中小学生正念注意觉知的发展及其与心理健康的关系,并考察情绪调节和积极重评在其中起到的中介作用。研究采用追踪设计,来自江西地区两所小学(4到6年级)和两所中学(7到9年级)的共1251名学生(男生691人,女生560人)在间隔半年的两个时间点分别填写了测量正念注意觉知、心理健康(生活满意度、抑郁、焦虑、学业压力)、情绪调节以及积极重评的问卷。结果表明：(1)中学生正念注意觉知显著低于小学生;(2)中小学生正念注意觉知与两个时间点的情绪调节、积极重评及心理健康均显著相关;(3)跨时间点中介效应检验结果表明,在中小学生正念注意觉知和各心理健康变量的关系中,情绪调节中介效应均显著,积极重评中介效应均不显著。结论：中小学生正念注意觉知与心理健康密切相关,正念注意觉知通过情绪调节能力间接作用于中小学生心理健康。     

三种常用DIF检测方法的比较研究

本研究在对DIF作出新的更为严格的界定、对三种常用的DIF检澍方法进行详细介绍的基础上．以1999年高考英语试卷75道选择题为研究材料,对三种常用的DIF检测方法进行了实证研究。结果表明：MH方法与SIBTEST方法检测的敏感性较STND方法高;MH方法与SIBTEST方法检出的一致性很高;SIBTEST方法具有较好的性能,在实际应用中可以作为首选的方法;在进行DIF检测时,样本容量在1000左右为宜。     

人口老龄化呼唤老年医疗保障

我国人口老龄化进程加快,迫切需要建立健全老年人的医疗保障体系。简述了人口老龄化与老年人医疗卫生问题与支付能力,说明了在我国建立老年医疗保障制度的重要性及意义,并提出：针对社区老年人医药费用的不同负担形式与经济承受能力,建立不同收入、不同需求、不同形式的老年医疗保障制。