Improved picture naming in chronic aphasia after TMS to part of right Broca's area: an open-protocol study

Functional imaging studies with nonfluent aphasia patients have observed "over-activation" in right (R) language homologues. This may represent a maladaptive strategy; suppression may result in language improvement. We applied slow, 1 Hz repetitive transcranial magnetic stimulation (rTMS) to an anterior portion of R Broca's homologue daily, for 10 days in four aphasia patients who were 5-11 years poststroke. Significant improvement was observed in picture naming at 2 months post-rTMS, with lasting benefit at 8 months in three patients. This preliminary, open trial suggests that rTMS may provide a novel treatment approach for aphasia by possibly modulating the distributed, bi-hemispheric language network.     

A draft model aggregated code of ethics for bioethicists

Bioethicists function in an environment in which their peers--healthcare executives, lawyers, nurses, physicians--assert the integrity of their fields through codes of professional ethics. Is it time for bioethics to assert its integrity by developing a code of ethics? Answering in the affirmative, this paper lays out a case by reviewing the historical nature and function of professional codes of ethics. Arguing that professional codes are aggregative enterprises growing in response to a field's historical experiences, it asserts that bioethics now needs to assert its integrity and independence and has already developed a body of formal statements that could be aggregated to create a comprehensive code of ethics for bioethics. A Draft Model Aggregated Code of Ethics for Bioethicists is offered in the hope that analysis and criticism of this draft code will promote further discussion of the nature and content of a code of ethics for bioethicists.     

Performance determined instruction for training in remedial reading

A system called Performance Determined Instruction (PDI) is presented as a methodological tactic for training in remedial reading. The system incorporates aspects of binary logic, instrumental conditioning, and programmed instruction. Results suggest that PDI is a high-precision instructional procedure effective in obtaining desired changes in reading-task performance.     

On shame and the perceived credibility of sexual assault allegations

Despite the high incidence of sexual assault, doubt about allegations is common. Previous research suggests that victims expressing positive or no emotion are perceived as less credible than those expressing negative emotions. However, little is known about which specific negative emotional expressions contribute to credibility in this context. In two studies (N = 623), participants read a date rape vignette. The alleged victim's statement was paired with a picture of a female person expressing either shame, sadness, or no emotion. Participants rated the credibility of her account and completed a measure of rape myth acceptance. Controlling for rape myth acceptance, allegations were perceived as more credible when accompanied by an expression of shame versus sadness (a negative, low arousal control condition). It is critical to be aware of the shame-credibility bias in this context to intervene and support those who have experienced sexual assault.     

Videtur Quod: On Method in Theology

Abstract: Theological language has always faced a fundamental dilemma: it seeks to put the divine reality into limited human language. While this dilemma can obfuscate our theological pathways, it can also generate a new awareness of the task and possibilities of the discipline. New testimonials, or uniquely accented human experiential utterances, have emerged in theological discourse in the past decades, greatly increasing our vision of the expansiveness of theology. The tools for integration into systematic or discursive development are still, however, lacking. This article suggests that an extension of the innovative methodology of Thomas Aquinas, beginning and ending with ‘what seems’ to be the case, putting testimony into discursive forms, and testing for a fittingness with the mysterious and excessive mystery of the divine reality, offers a promising path for discerning common and trustworthy theological language.     

A theory of international bioethics: the negotiable and the non-negotiable

The preceding article in this issue of the Kennedy Institute of Ethics Journal presents the argument that "moral fundamentalism," the position that international bioethics rests on "basic" or "fundamental" moral prinicples that are universally accepted in all eras and cultures, collapses under a variety of multicultural and postmodern critiques. The present article looks to the contractarian tradition of Hobbes and Locke -- as reinterpreted by David Gauthier, Robert Nozick, and John Rawls -- for an alternative justification for international bioethics. Drawing on the central themes of this tradition, it is argued that international bioethics can be rationally reconstructed as a negotiated moral order that respects culturally and individually defined areas of nonnegotiability. Further, the theory of a negotiated moral order is consistent with traditional ideals about human rights, is flexible enough to absorb the genuine insights of multiculturalism and postmodernism, and yet is strong enough to justify transcultural and transtemporal moral judgments, including the condemnation of the Nazi doctors at Nuremberg. This theory also is consistent with the history of the ethics of human subjects experimentation and offers insights into current controversies such as the controversy over changing the consent rule for experiments in emergency medicine and the controversy over exempting certain clinical trials of inexpensive treatments for preventing the perinatal transmission of AIDS from the ethical standards of the sponsoring country.     

Effects of Predator-Induced Stress and Age on Working Memory in Rats

The Psychological Record - The effects of age and predator-induced stress, by exposing rats to a cat, were examined during subsequent testing of spatial working memory. Male rats (3 months and 20...     

An extension of item analysis procedures to the case of polychotomous response

Classical item analysis procedures were developed for dichotomously scored items and do not apply to items allowing multiple correct responses. Maximum likelihood procedures analogous to those employed in polychotomous bio-assay are presented which yield estimates of the sets of parameters for items having multiple nonordered responses. Expressions for the estimates of the asymptotic variances of the item parameters and on overall chi-square goodness of fit test are also provided.