中国医药创新面临的挑战及其应对

当下, 医药产业创新可持续发展已成为满足人民生命健康﹑维护国家安全、建设科技强国, 参与国际战略竞争的制高点和关键。历经十几年的发展﹐中国医药创新环境得到非常显著的改善, 但仍面临新的挑战, 中国医药创新又到了再次转型的关键节点。大力发展医药创新需要的不仅是政府资金支持或单项政策出台, 更是举国体制下清晰的顶层设计, 融合全产业链条(基础/临床研究、监管、支付等)建立起科学、完善的政策机制, 在双循环新发展格局下构建中国医药创新高质量发展的必然要求。

     

基本医疗卫生改革的政治伦理、市场逻辑与未来走向

基本医疗卫生改革是当前实现“2030健康中国”和新时代下践行人民健康优先战略的一项制度创新。然而,现实中改革仍面临医疗资源配置不均和医疗服务供给效率不高的双重困境。本质上,医疗服务具有公利性与私利性二元属性,进而延伸出立足于公利性属性,基本医疗卫生改革应当坚守“人人公平享有”的政治伦理,鉴于私利性属性改革需要维护医疗市场主体合法逐利的正当权利,政府公利性创造与市场私利驱动是辩证性的哲学思考。我国医改未来应以公民健康与福祉共享为价值依归,始终坚持政府严守底线、市场有序竞争、社会和谐稳定的发展主线。

     

我国民众对SARS信息的风险认知及心理行为

采用分层抽样的调查方法,对全国17个城市的4231名市民进行了SARS疫情中风险认知特征和心理行为的研究。结果发现：（1）负性信息,包括患病信息和与自身关系密切的信息,更易引起民众的高风险认知; 正性信息,包括治愈信息和政府防范措施的信息,能降低个体风险认知水平。（2）我国民众5月中旬风险认知因素空间位置分析结果表明, SARS病因处于不熟悉和难以控制一端,“愈后对身体的影响和有无传染性”处于不熟悉一端,这是引起民众风险意识的主要因素。（3）结构方程分析结果表明,SARS疫情信息是通过风险认知对个体的应对行为、心理健康产生影响的, 并初步验证了风险评估、心理紧张度、应对行为和心理健康等指标对于危机事件中民众心理行为的预测作用     

知情同意的临床实践存在的问题及对策

临床医疗实践中贯彻实施知情同意原则旨在保护病人的权益不受侵犯,然而知情同意原则实施起来并不简单,它常常会受到主客体两方面种种因素的制约,陷入意想不到的困境。分析了知情同意原则在实施过程中可能出现的一些难以回避的问题,并针对这些问题探讨了若干对策。     

基于CiteSpace近10年中医药科技伦理研究知识图谱分析

追踪和探索近10年中医药科技伦理研究的趋势与热点。检索中国知网数据库近10年相关文献,应用CiteSpace 6.1.R6软件分别对纳入的238篇文献的作者、机构、关键词绘制知识图谱并进行分析。从2013年1月1日—2023年1月1日,中医药科技伦理领域发文量总体呈波动性上升趋势。频数最多的5个关键词为伦理审查、中医药、临床研究、中医、伦理。研究显示中医药研究伦理审查、中医药现代化面临的伦理问题、中医学理论在伦理领域的新发展、中国传统医德研究是该领域关注的重点。大医精诚的相关研究可能成为未来研究方向。

     

Cavanagh and Leclerc shape-from-shadow pictures: do line versions fail because of the polarity of the regions or the contour?

Shape-from-shadow perception fails when the contour bordering a shadowed area is reduced to a black line, and the shadow area becomes white. It might be that the polarity of the shadowed and illuminated areas has to be from dark on the shadowed side to light on the illuminated side for successful perception. Or it may be that the line, which has two contours, has one too many for shape-from-shadow processing. Alternatively, the problem might be that one of the contours of the line is incorrectly polarised. To test these explanations, three shape-from-shadow figures were prepared, each depicting the same referent--an elderly person. All three figures had two correctly polarised areas. One figure had a correctly polarised contour at the border between the areas. One had two correctly polarised contours. The other had one correctly polarised contour and one incorrectly polarised contour. The referent of the figure with one incorrectly polarised contour was the one difficult to make out. The result has implications for several theories, including an account of a demonstration by Hering involving penumbra.     

中小学生认知能力发展水平测验的研究

以皮亚杰的认知发展理论为基础,采用皮亚杰及其学生研究认知发展时的任务为测验题目,编制成测量中小学生认知能力发展水平的测验.通过对2240名中小学生施测,结果表明本测验不仅具有很好的信度和效度,而且也具有适中的难度.然后以一所中学特长班学生为被试,通过对他们进行测量,并将测验结果与同年级普通班学生的认知成绩进行比较,结果存在很明显的差异.最后对中小学生认知能力发展水平测量问题进行了探讨.     

Fitting a psychometric function to price judgments: an analysis of consumers' discounted prices

We examined a psychometric function of price judgment, comparing the mental ruler model, which predicted inverted S-shaped psychometric function, with a power function. Subjects, 102 citizens living in Japan, were asked to rate satisfaction with specified discounted prices. Analysis indicated that predictions of the mental ruler model gave a better fit than those of the power function.     

Visual perception of surface wrinkles

To study the relationship between visual perception of magnitude of wrinkles and geometrical parameters of surfaces, four potentially relevant parameters of the surface profile were considered: the variance (sigma2), the cutting frequency (Fc), the effective disparity curvature (Dce) of the wrinkled surface over the eyeball distance of the observer, and the frequency component of the disparity curvature (Dcf). Analysis of garment seams with varying amount of pucker showed that, while the logarithm for each of these four parameters has a strong linear relationship with the visually perceived magnitude of wrinkles, following the Fechner Law, the effective disparity curvature (Dce) and the frequency component of the disparity curvature (Dcf) with visual perception appeared stronger. This modeling may be an objective method for measuring magnitude of surface wrinkles.     

执行功能中认知灵活性发展的研究进展

近十多年以来,执行功能已成为研究的热点和前沿。认知灵活性是执行功能的主要成分,它对个体能力发展和对环境适应的方面起着重要作用。该文从认知灵活性的本质、发展、研究方法及其与教育的关系进行探讨。