Some problems of Wilson's disease

The Leipzig Center for Wilson's Disease in the GDR is charged with the registration and diagnosis of all homozygous Wilson gene carriers, the clarification of all suspected cases, including the heterozygote test, and the co-ordination of long-term treatment. At present, there are 78 recorded Wilson gene carriers living. On the basis of our own comprehensive observations and investigations over prolonged periods of time, questions concerning pathogenesis, genetics, diagnosis and therapeutic measures, including their side-effects, are dealt with.     

A new Visual Aesthetic Sensitivity Test (VAST): II. cross-cultural comparison between England and Japan

A comparison was made of the scores of 171 Japanese boys and 156 Japanese girls, and of 204 English boys and 165 English girls, on the Visual Aesthetic Sensitivity Test. Also compared were 145 male and 163 female Japanese students, with 38 male and 73 female English students. Japanese children had scores significantly higher than English children, while Japanese students had scores significantly lower than English students. There was little evidence of age increments in score for either group of children. Difficulty levels of the 42 item-pairs were very similar in the two cultures, as were internal (split-half) reliabilities. It is concluded that cultural differences between the two countries, as far as visual aesthetic appreciation is concerned, seem at best minimal.     

Facial myokomias in brain stem tumors]

Four cases of brain-stem tumor were described, in which myokymias were electromyographically derived from the region of several cerebral nerves. An attempt is made to interpret the effects of twitching by reference to the electromyogram. Myokymias are a positive indication of organic brain stem damage. The use subtle techniques of electromyographic examination shows that this muscular hyperkinesis is not so infrequent a symptom as is generally believed.     

Problems and prospects in group psychotherapy research

The scientific basis of psychotherapeutic findings involves a number of difficulties which are above all connected with the insufficient state of basic research in this field. In this situation, significant advances can only be expected on the basis of a systematic long-term investigation and research programme. This applies in particular to the problems of personality and efficiency diagnostics and to group process research. On the basis of some intermediate results, it is shown that by the combined and systematic use of procedures a number of possibilities for the differentiated recording of the complex processes in therapeutic groups can be obtained.     

Time errors and differential sensation weighting

Sixteen pairs of successive tones, with different amplitude combinations, were presented with 16 combinations of tone duration and interstimulus interval. A separate group of 12 subjects was assigned to each presentation condition and made comparative loudness judgments for each of the pairs. Perceived within-pair loudness differences were scaled by a Thurstonian method using the subjective width of the "equal" category as the unit. The scale differences were well described by weighted linear combinations of the sensation magnitudes of the tones in the pairs. The time error can be regarded as an effect of this differential weighting. For the longer interstimulus intervals, the weight of the second tone was the greater, causing the usual inverse relation between time error and stimulus intensity level. For the shorter interstimulus intervals, these effects were reversed. An analysis of the pattern of weights led to the development of two models, one of which is a generalization of Michels and Helson's time error model. The weights could be interpreted as reflecting the differential efficiency of the loudness information from the two compared stimuli.     

Conflict play and its modification in the course of treating children

The authors report their experience with a special form of psychodrama for the treatment in small groups of neurotic children aged five to fifteen. The acting out of ambivalent, partly unconscious and restrained tendencies and inclinations by playing, i.e., by taking roles in spontaneous performances, is followed by alternation of identification in the group and, possibly, careful indirect verbalization by the therapeutist and/or group, of which the purpose is to arrive at a reorientation of the attitudes of patients and a consolidation of the newly won attitude.     

Stimulus control of free-operant avoidance: The contribution of response rate and incentive relations between multiple-schedule components

The associations formed in the components of a multiple schedule can be classified as (1) stimulus-response (S-R) associations and (2) stimulus-reinforcer (S-S^R) associations. The present experiments sought to determine the individual contribution of these S-R and S-S^R associations to stimulus control by manipulating them independently. Responses postponed shocks by 25 sec in the presence of a tone alone and a light alone in all experiments. The contingencies programmed in the absence of both tone and light established a reference for the S-R and S-S^R associations in tone and in light. All four possible combinations of signalling response increase or decrease together with incentive increase or decrease were studied. Although the influence of the contingencies operating in the absence of tone and light was difficult to detect from response rates in tone or light, presenting tone and light together revealed clear effects. Response rates in tone and light together relative to those in either alone depended upon the contingency operating in the absence of tone and light. Stimulus-response and stimulus-reinforcer associations appeared to counteract each other when in opposition and combine together to enhance each other when in agreement. This suggested that the associations of a stimulus to response and to incentive combine algebraically in determining stimulus control. An algebraic analysis in terms of the S-R and S-S^R associations conditioned to the stimulus elements comprising the training and test stimuli accounted for the observed patterns of data.     

Hardware and software evolution of an adaptive ability measurement system

A software system for the administration of six different strategies of adaptive ability tests in a variety of formats was developed both on a large-scale time-sharing system and on a real-time minicomputer system. Factors influencing both hardware selection and software design are discussed.