Age-related changes in working and reference memory performance and locomotor activity in the Wistar rat

Wistar rats of three age groups were tested in an automated tunnel-maze system of variable geometry to investigate whether changes in spontaneous locomotor activity and in learning and memory develop differentially or in a correlated fashion as a function of age. Senescent (30 months) as well as mature-adult (17 months) rats showed an age-correlated decline of locomotor activity as compared to the mature-young (5 months) group. Both working-memory (measured as within-trial arm discrimination performance) and reference-memory (measured as avoidance of "blind alley" visits) were severely affected in the senescent group, whereas the middle-aged animals suffered only from a working-memory deficit. The findings provide evidence that locomotor deficits do not necessarily interfere in the assessment of age-related changes in cognitive performance. Furthermore the results support the hypothesis that working and reference memory have different underlying physiological correlates and that these neuronal systems are differentially affected by the aging process.     

Listeriosis of the central nervous system in children beyond the neonatal period

Observations on three children with neurolisteriosis (one case of meningitis, two cases of meningoencephalitis, each Serovar 4 b), show that even after the neonatal period, listeriosis must not be ignored in the process of diagnosis and therapy. It is the bacteriological examination of the cerebrospinal fluid, together with the blood culture, and not clinical symptoms and serology that guarantee a timely diagnosis and therapy (ampicillin and gentamicin).     

Sleep in the dove Zenaida asiatica

Electrographic and behavioral observations were made in five adult birds of the genus Zenaida asiatica. Five different vigilance states were quantitated: (1) Active waking (Aw) was characterized by constant behavioral activity; the nuchal electromyogram was tonically active with bursts associated to movements. The electroencephalographic pattern was low voltage and high frequency. (2) Quiet waking (Qw) was characterized by diminished behavioral activity and the EEG pattern was similar to that of Aw. (3) Drowsiness (D) was characterized by behavioral calm. Frequency of cerebral activity diminished progressively, but there were short periods of desynchronization corresponding to brief awakenings. (4) Slow wave sleep (SWS); during this period there was behavioral rest and EEG pattern of continuous slow waves and the nuchal EMG was tonically reduced. Spindles of sleep were not observed. (5) Paradoxical sleep (SP), behaviorally characterized by phasic manifestations consisting of noddings originated by rapid falling down of head and bursts of rapid eye movements. EEG activity was like that of waking state. EMG activity was maintained at the same level as during SWS but sometimes it decreased lightly. Total atonie was not observed. Sleep percentages were higher when recordings were done during the nocturnal period.     

Paranoid character and the intolerance of indifference.

This paper suggests that aspects of paranoid character are structured around fantasies of magical and concrete connectedness to objects; these fantasies serve to avoid the terrors of object inconstancy. The authors describe how these fantasies are expressed in the psychoanalytic situation and explore their relation to common paranoid phenomena. The paranoid person must maintain these fantasies of connectedness at all cost or risk experiencing unbearable indifference between self and object. Paradoxically, the sacrifice of self and object boundaries inherent in these fantasies makes object constancy even more difficult to achieve because of the secondary defensive use of anger mobilized to protect the boundaries of the self.     

Mothers with hostile, Type A predisposing child-rearing practices.

The authors examined characteristics of Finnish mothers (N = 924) who use hostile child-rearing practices (i.e., they ignore the child, are punitive and irritable, and perceive the child as a burden), practices that have been shown (R?ikk?nen & Keltikangas-J?rvinen, 1992) to predispose children to Type A behavior. The results of this study indicate that two factors--Type A behavior in the mothers and the mothers' sociodemographic background (low occupational status, low educational level and young age)--increase the probability of the mothers' treating their children in a hostile manner. Also, the mothers of boys in this study reported more hostile child-rearing practices than the mothers of girls did.     

Psychological compensation: a theoretical framework.

The 2 main objectives of this article are to review a variety of literatures in which the concept of compensation is used and to integrate the results of this review into a general framework of compensation. The review focuses on 4 domains of psychological inquiry: compensation for sensory handicaps, cognitive deficits, interpersonal losses, and brain injury. In the proposed framework, underlying dimensions and 4 basic steps in the progression of compensatory behavior are distinguished. The latter include origins, mechanisms, forms, and consequences. Finally, we describe ways in which researchers in particular domains can benefit from the global, process-oriented framework we propose. For most of the areas of compensation research reviewed, investigators can profit from a consideration of a broader selection of dimensions, additional steps in the process, alternative outcomes, and both objective and subjective assessment procedures.     

Predictors of short-term treatment outcome in bulimia nervosa inpatients.

Recent studies, mostly performed on bulimic outpatients, did not find consistent predictors of treatment outcome in bulimia nervosa. This is the first study to investigate anamnestic and clinical factors predictive of the short-term outcome of hospital treatment in 31 female bulimia nervosa patients with a mean age of 22.9 yr. Treatment outcome was assessed by several self-rating instruments measuring different features of the specific and unspecific psychopathology of bulimia nervosa. The most relevant predictors of the outcome of the 8-week hospital treatment were duration of previous inpatient treatments for bulimia, the intensity of anorexic tendency and the pretreatment level of depression. The majority of predictors tested did not show a strong relationship to treatment outcome. The findings are discussed in relation to results of other studies as well as to possible implications for treatment and research.     

Quantitative scores of normal and abnormal subjects on Initial-letter Word-association Test.

The quotient of the mean quantitative score on Initial-letter Word-association Test for 193 normal subjects was significantly higher than the quotient of the mean quantitative score of 44 abnormal (psychotic) subjects. This is interpreted as meaning that, in general, the normal subjects have predominantly a positive attitude towards their surrounding world in contradistinction to the abnormal subjects whose attitude was predominantly negative, ambivalent, and repressive. On the other hand, the mean of the quotients of the quantitative scores of the 44 abnormal subjects was higher than the mean of the quotients of the quantitative scores of the normal subjects which suggests increased oral tendencies of the abnormal subjects expressed much as the unwarranted optimism of small children.     

Slow alpha in the EEG power spectrum as an indicator for conceptual arousal]

Based on previous findings (B?sel et al., 1990) it was assumed that in concept learning tasks generating on hypotheses on a concept which has to be developed is accompanied by increases of the Alpha 1 power (7.5-10 Hz) in the spontaneous EEG activity. In this study 16 subjects performed five problem solving tasks with similar processing requirements. EEG data were analyzed by means of post hoc comparisons of subjects differing in performance quality. Additionally, four control tasks were employed in which, based on previous studies, variations in the Theta frequency range were expected. An effect in the Alpha 1 frequency band was observed in tasks requiring reconstructive recall or testing the usefulness of an mathematical algorithm. The creation of a rank order or mental map is accompanied by power increases in the lower portions of the Alpha 1 frequency band (7.5-8.5 Hz). Moreover a high amount of controlled variance (eta2 up to 34%) was obtained for this effect. Increases in EEG Theta power, which presumably indicate subjects' component analysis, were found before the subjects recognized parts of geometric figures or before relevant features in the "buddhist monk problem" were discriminated. The dynamics of EEG power over time is in examples of frequency/time plots in a figure, illustrated.