The association between intelligence level and brain volume measures: a negative finding

Ratings of pre-morbid intelligence level, derived from the hospital charts of 26 chronic schizophrenics, were correlated with the post-mortem brain volume measures of cortex, white matter, central grey matter, and ventricles. Contrary to hypothesis, no significant correlations were found.     

Sample size determinations for the two rater kappa statistic

This paper gives a method for determining a sample size that will achieve a prespecified bound on confidence interval width for the interrater agreement measure,. The same results can be used when a prespecified power is desired for testing hypotheses about the value of kappa. An example from the literature is used to illustrate the methods proposed here.     

Generalized approaches to the maxbet problem and the maxdiff problem,with applications to canonical correlations

Van de Geer has reviewed various criteria for transforming two or more matrices to maximal agreement, subject to orthogonality constraints. The criteria have applications in the context of matching factor or configuration matrices and in the context of canonical correlation analysis for two or more matrices. The present paper summarizes and gives a unified treatment of fully general computational solutions for two of these criteria, Maxbet and Maxdiff. These solutions will be shown to encompass various well-known methods as special cases. It will be argued that the Maxdiff solution should be preferred to the Maxbet solution whenever the two criteria coincide. Horst's Maxcor method will be shown to lack the property of monotone convergence. Finally, simultaneous and successive versions of the Maxbet and Maxdiff solutions will be treated as special cases of a fully flexible approach where the columns of the rotation matrices are obtained in successive blocks.The author is obliged to Henk Kiers for computational assistance and helpful comments.     

Cerebral hemispheric mechanisms in the retrieval of ambiguous word meanings

Targets related to ambiguous primes were projected to the left and right visual fields in a lexical priming experiment with stimulus onset asynchronies (SOA) of 35 and 750 msec. Right visual field results were similar to our earlier results with central projection (G. B. Simpson & C. Burgess, 1985, Journal of Experimental Psychology: Human Perception and Performance, 11, 28-39). Facilitation was found for the more frequent meaning at both SOAs and a decrease in facilitation for the less frequent meaning at the longer SOA. In contrast, left visual field results indicated a decay of facilitation for the more frequent meaning at the longer SOA, while activation for the subordinate meaning increased. Results suggest that, while automatic processing occurs in both hemispheres, only the left hemisphere engages in controlled processing of ambiguous word meanings. In addition, the present results support the idea that the right hemisphere has a special role in ambiguity resolution and that the right hemisphere lexicon possesses a richer endowment than earlier thought.     

Naltrexone-reversible pain suppression in the isolated attacking mouse

Fighting pairs of isolated DBA/2 mice showed a significant increase in tail-flick response latencies independent of whether opponents were losing or winning the combat. The effect lasted less than 10 min in both animals. Elevated pain thresholds were also found in isolates that attacked a nonaggressive conspecific, and were prevented by naltrexone (0.2 mg/kg), while a larger dose (1.0 mg/kg) inhibited the attack behavior. A small increase in pain threshold was observed after exposure of isolates to the test box alone, while isolation per se had no effect on baseline tail-flick latencies. The data demonstrate that endogenous pain suppressing systems are activated during attack and suggest that this opioid-mediated antinociception is a correlate of the isolation syndrome, reflecting enhanced arousal of the attacking animal.