Differential indication of trimipramine - results of a controlled multiclinical study]

The antidepressants trimipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective und psychomotoric symptoms. The panthymoleptic action of trimipramine and other antidepressants is discussed with reference to these results. Trimipramine influences psychotic states, especially if in depression anxiety is combined with agitation, also in hypochondriac forms of depression.     

Epilepsy by looking at patterns]

The author, after pointing out the rare occurence and peculiarities of pattern-sensitive forms of epilepsy, reports the case of a seven-year-old boy with infantile cerebral paresis characterized by symptomatic attacks, who was observed to show absence-like conditions when looking at small-checkered patterns of nylon fabric. Grasping and looking at such fabrics assumed the form of an addiction, with a sense of pleasure being believed to be derived therefrom. Although anticonvulsive therapy resulted in attacks of epilepsy being no longer detectable clinically and by electroencephalography, seizures were still triggered by looking at patterns. Also discussed in this article is the problem of transition from real to psychogenic attacks.     

Time errors are perceptual

Summary Methods for the measurement of time-errors (TEs) in the comparison of successive stimulus magnitudes are discussed. Combining a Thurstonian scaling method with the assumption of a fixed subjective width of the equal category, independent of stimulus level, a ratio scale for subjective differences within pairs of successive stimuli is derived. In a tone duration comparison experiment, with the TE defined in the terms of these subjective duration differences, data from four experimental groups were compared, the groups using different modes of judging and responding. Only minor effects of this factor were found, and hence it is concluded that the TE is a true perceptual phenomenon rather than an effect of response bias, criterion bias, or mediating verbal responses to the absolute level of stimulation. The quantitative results are interpreted in terms of a general model for the comparison of successive stimuli, employing the concepts of adaptation and differential weighting of sensation magnitudes.This investigation was supported by grants to the author from the University of Stockholm and from the Swedish Office of Administrative Rationalization and Economy (for computer time), and by grants to Mats Björkman and Hannes Eisler from the Swedish Council for Social Science Research, whose free consultation service at the Department of Statistics, University of Stockholm, also benefited the author.     

Determination of the variation in conduction speed of motor fibers and the effects of diphenylhydantoin (Phenytoin) and diazepam (Faustan)]

The variation in the speed of conduction of motor fibers of the ulnar nerve was determined by Hopf's double-stimulus method and compared with values obtained from the duration of muscular response potentials for differently spaced points of stimulation. However, the values obtained from the difference of the duration of response potentials are inadequate since the duration of potentials cannot always be determined accurately. After a ten-day administration of faustan (15 mg per day) or phenytoin (300 mg per day) there was observed a decrease especially in the minimum rate of conduction of motor fibers of the ulnar nerve.     

Assessing Facets of Mindfulness in the Context of Work: The Mindfulness@Work Scale as a Work-Specific,Multidimensional Measure of Mindfulness

The mindfulness at work literature lacks a multi-faceted measure of mindfulness that is applicable in the work context. Building on predominantly clinically oriented, multi-faceted mindfulness measures, we aimed to develop and validate such a measure and to provide first insights into differential validities of mindfulness subfacets for work outcomes. Data from seven work samples (overall n = 4,977) provided support that (a) a 4-factor structure representing the subfacets of Describing, Nonreactivity, Nonjudging, and Act with Awareness replicates across samples; (b) subfacets and overall scale have good internal consistency and retest reliability; (c) the measure demonstrates convergent and discriminant validity; (d) it demonstrates criterion-related validity for well-being, motivational, and interpersonal work outcomes; (e) the Mindfulness@Work Scale explains variance in outcome variables above a unidimensional measures of mindfulness supporting its incremental validity. Furthermore, relative weights and incremental validity analyses revealed differential validities of subfacets of the Mindfulness@Work Scale in relation to positive psychological states versus psychological distress. Overall, findings suggest that the Mindfulness@Work Scale has good psychometric properties and that a differentiation of subfacets provides novel insights into the role of mindfulness for work outcomes.