Stem cell research in a Catholic institution: yes or no?

Catholic teaching has no moral difficulties with research on stem cells derived from adult stem cells or fetal cord blood. The ethical problem comes with embryonic stem cells since their genesis involves the destruction of a human embryo. However, there seems to be significant promise of health benefits from such research. Although Catholic teaching does not permit any destruction of human embryos, the question remains whether researchers in a Catholic institution, or any researchers opposed to destruction of human embryos, could participate in research on cultured embryonic stem cells, or whether a Catholic institution could use any therapy that ultimately results from such research. This position paper examines how such research could be conducted legitimately in a Catholic institution by using an ethical analysis involving a narrative context, the nature of the moral act, and the principle of material cooperation, along with references to significant ethical assessments. It also offers tentative guidelines that could be used by a Catholic institution in implementing such research.     

The eyebrow frown: a salient social signal

Seven experiments investigated the finding that threatening schematic faces are detected more quickly than nonthreatening faces. Threatening faces with v-shaped eyebrows (angry and scheming expressions) were detected more quickly than nonthreatening faces with inverted v-shaped eyebrows (happy and sad expressions). In contrast to the hypothesis that these effects were due to perceptual features unrelated to the face, no advantage was found for v-shaped eyebrows presented in a nonfacelike object. Furthermore, the addition of internal facial features (the eyes, or the nose and mouth) was necessary to produce the detection advantage for faces with v-shaped eyebrows. Overall, the results are interpreted as showing that the v-shaped eyebrow configuration affords easy detection, but only when other internal facial features are present.     

Motivation influences the underestimation of cumulative risk

Past research has shown that people typically underestimate the cumulative risk of events. This effect has mainly been interpreted as resulting from the use of cognitive heuristics and judgment strategies, such as availability or anchoring and adjustment. The authors suggest that motivational processes can be an additional force in the generation of cumulative risk estimates. Using an experimental design, Study 1 shows that people underestimate the cumulative risk of infection with sexually transmitted diseases of appealing prospective sexual partners by using risk-irrelevant information for their judgment. Using a correlational design, Study 2 demonstrates that people underestimate the cumulative risk of being infected with a sexually transmitted disease and that commitment to the present partner is directly related to a low cumulative risk estimate as well as indirectly through its effect on the perceived risk of the present partner. Together, the two studies demonstrate that motivation influences the underestimation of cumulative risk.     

‘Peer review’ culture

A relatively high incidence of unsatisfactory review decisions is widely recognised and acknowledged as ‘the peer review problem’. Factors contributing to this problem are identified and examined. Specific examples of unreasonable rejection are considered. It is concluded that weaknesses of the ‘peer review’ system are significant and that they are well known or readily recognisable but that necessary counter-measures are not always enforced. Careful management is necessary to discount hollow opinion or error in review comment. Review and referee functions should be quite separate.     

“I'll wait for the English one”: COVID-19 vaccine country of origin,national identity,and their effects on vaccine perceptions and uptake willingness

Vaccines can play a crucial role in reducing the negative outcomes of pandemics. In this paper we explore how vaccine perceptions and uptake willingness can be affected by vaccine-related information, the vaccine's country of origin, and national identity. Study 1 (N = 800) showed that a vaccine manufactured by China was perceived more negatively compared to vaccines from the UK, Germany, and Chile. Providing vaccine effectiveness information (83%) increased preference for waiting for an alternative vaccine and reduced perceived effectiveness of a vaccine from China. Brexit supporters perceived vaccines as less safe in general, and particularly thought of a vaccine from China as less competent, effective, and trustworthy, and were less prepared to have it. Study 2 (N = 601) largely replicated findings of Study 1 regarding the effects of a vaccine's country of origin. Moreover, participants who reported a higher sense of British superiority reported more negative attitudes towards a vaccine from China. However, apart from the aforementioned main effects of Study 2, our attempt to manipulate British identity vis a vis a Global identity in order to examine particular national-identity related outcomes was not successful. Overall, vaccine characteristics can interact with various social psychological factors, potentially affecting people's perceptions and willingness to uptake particular measures to support personal and public health.     

Development of orientation discrimination in infancy

It has previously been found by us, with a visual evoked potential (VEP) measure, that orientation discrimination of dynamic patterns in infants can be demonstrated from around 6 weeks after birth. Experiments are reported in which orientation discrimination was measured behaviourally, in two infant control habituation procedures, with both dynamic and static patterns. When dynamic patterns identical to those in our previous VEP studies were used, the first positive evidence of orientation discrimination was found at around 6 weeks postnatally. The time course of both the VEP and the behavioural measures was similar. However, with static patterns, evidence of orientation discrimination by newborns was found if the infants were allowed to compare the habituated and novel orientations in a paired simultaneous comparison after habituation, but was not found when the habituated and novel stimulus were presented sequentially. The positive evidence of orientation discrimination in newborns supports the hypothesis that some form of orientationally tuned detectors can be used for discrimination of static patterns at birth. However, some developmental change over several weeks seems to be required before a positive electrophysiological VEP response can be measured for dynamic patterns changing in orientation.     

Use of population-specific parameters in generating WAIS-R short forms

One method of increasing the validity of WAIS-R short forms in estimating the standard WAIS-R Full Scale IQ is by using population-specific parameters in generating WAIS-R short forms. Three studies were conducted to evaluate (1) the contribution of age-scaled scores in generating accurate short-form Full Scale IQ, (2) the psychometric properties (validity and reliability) of WAIS-R subtests with a heterogeneous psychiatric population and subsequent development of short forms based on these properties, and (3) the validity of these short forms with respect to Silverstein's (1982) and Cyr and Brooker's (1984) 2- and 4-subtest combinations. Analyses showed (1) the use of age-scaled scores did not increase validity, (2) different subtest combinations were generated based on the population-specific parameters, and (3) increases in validity occurred for some short forms derived from the clinical sample. Despite increases in validity, clinicians and researchers are cautioned about the use of short forms in clinical practice.     

Complexity and measurement of hypnotic susceptibility: a comment on Coe and Sarbin's alternative interpretation.

Coe and Sarbin's claim that a single role skill dimension accounts for individual differences in hypnotizability is not supported by an empirical analysis. We suggest that current measures of hypnotic susceptibility are not only factorially complex but contain a sizable nonhypnotic variance component. Implications for the assessment of "true" hypnotic susceptibility are discussed.     

The impact of a new emotional self-management program on stress, emotions, heart rate variability, DHEA and cortisol

This study examined the effects on healthy adults of a new emotional self-management program, consisting of two key techniques, “Cut-Thru” and the “Heart Lock-In.” These techniques are designed to eliminate negative thought loops and promote sustained positive emotional states. The hypotheses were that training and practice in these techniques would yield lowered levels of stress and negative emotion and cortisol, while resulting in increased positive emotion and DHEA levels over a one-month period. In addition, we hypothesized that increased coherence in heart rate variability patterns would be observed during the practice of the techniques. Forty-five healthy adults participated in the study, fifteen of whom acted as a comparison group for the psychological measures. Salivary DHEA/DHEAS and cortisol levels were measured, autonomic nervous system function was assessed by heart rate variability analysis, and emotions were measured using a psychological questionnaire. Individuals in the experimental group were assessed before and four weeks after receiving training in the self-management techniques. The experimental group experienced significant increases in the positive affect scales of Caring and Vigor and significant decreases in the negative affect scales of Guilt, Hostility, Burnout, Anxiety and Stress Effects, while no significant changes were seen in the comparison group. There was a mean 23 percent reduction in cortisol and a 100 percent increase in DHEA/DHEAS in the experimental group. DHEA was significantly and positively related to the affective state Warmheartedness, whereas cortisol was significantly and positively related to Stress Effects. Increased coherence in heart rate variability patterns was measured in 80 percent of the experimental group during the use of the techniques. The results suggest that techniques designed to eliminate negative thought loops can have important positive effects on stress, emotions and key physiological systems. The implications are that relatively inexpensive interventions may dramatically and positively impact individuals’ health and well-being. Thus, individuals may have greater control over their minds, bodies and health than previously suspected.