Risk factors for addictive disorders: a discriminant analysis on 374 addicted and 513 nonpsychiatric participants

Many common risk factors have been described in addictive disorders. Little is known about factors' respective contributions to discrimination of addicted and nonaddicted participants. Two large samples were compared including 513 nonpsychiatric participants and 374 addicted participants meeting the DSM-IV criteria for eating disorders, alcohol, or substance dependence. Twenty-six risk factors were assessed by interview or self-rating scales. A discriminant analysis determined the respective weight of each risk factor. One discriminant function emerged and characterized a depressive dimension. The results suggest that the different risk factors described in addiction could be related to a depressive dimension.     

A longitudinal assessment of executive function skills and their association with math performance.

The present study was designed to examine both concurrent and predictive associations between scores on a measure of executive function (EF) skills, the Contingency Naming Test (CNT), during the early school-age years. A secondary aim of the study was to examine the association between EF skills and mathematics performance. We administered tests of mathematics ability, and the CNT, to 178 children at ages 6 to 7, 8 to 9, and 10 to 11 years. From the CNT we obtained measures of response fluency/efficiency, working memory, and inhibition. The results demonstrate main effects of age on all CNT measures of EF, as anticipated, and inconsistent main effects of gender or mathematics learning disability status. Rates of improvement in EF varied as a function of the working memory demands present during a given task. There were differences in concurrent and predictive correlations for different CNT performance measures. EF scores obtained during the first assessment were as strongly associated with each other as they were with EF scores obtained four years later, suggesting a moderately stable source of individual differences on cognitive performance. EF scores at age 6 to 7 years were associated with concurrent and later mathematics scores, and most of these correlations were stronger than the significant associations found between response fluency on a baseline task (with no working memory demand) and mathematics performance. These findings have implications for the stability of EF skills during the school-age years, and the role of EF in early and later elementary school mathematics performance.     

An electro-physiological temporal principal component analysis of processing stages of number comparison in developmental dyscalculia

Developmental dyscalculia (DD) still lacks a generally accepted definition. A major problem is that the cognitive component processes contributing to arithmetic performance are still poorly defined. By a reanalysis of our previous event-related brain potential (ERP) data (Soltész et al., 2007) here our objective was to identify and compare cognitive processes in adolescents with DD and in matched control participants in one-digit number comparison. To this end we used temporal principal component analysis (PCA) on ERP data. First, PCA has identified four major components explaining the 85.8% of the variance in number comparison. Second, the ERP correlate of the most frequently used marker of the so-called magnitude representation, the numerical distance effect, was intact in DD during all processing stages identified by PCA. Third, hemispheric differences in the first temporal component and group differences in the second temporal component suggest executive control differences between DD and controls.     

Bias for consonantal information over vocalic information in 30-month-olds: cross-linguistic evidence from French and English

Using a name-based categorization task, Nazzi found in 2005 that French-learning 20-month-olds can make use of one-feature consonantal contrasts between new labels but fail to do so with one-feature vocalic contrasts. This asymmetry was interpreted as developmental evidence for the proposal that consonants play a more important role than vowels at the lexical level. In the current study using the same task, we first show that by 30 months French-learning infants can make use of one-feature vocalic contrasts (e.g., /pize/–/pyze/). Second, we show that in a situation where infants must neglect either a consonantal one-feature change or a vocalic one-feature change (e.g., match a /pide/ with either a /tide/ or a /pyde/), both French- and English-learning 30-month-olds choose to neglect the vocalic change rather than the consonantal change. We argue that these results suggest that by 30 months of age, infants still give less weight to vocalic information than to consonantal information in a lexically related task even though they are able to process fine vocalic information.     

The assessment of recognition memory using the Remember/Know procedure in amnestic mild cognitive impairment and probable Alzheimer’s disease

This study used the Remember/Know (R/K) procedure combined with signal detection analyses to assess recognition memory in 20 elders with amnestic mild cognitive impairment (aMCI), 10 patients with probable Alzheimer’s disease (AD) as well as matched healthy older adults. Signal detection analyses first indicated that aMCI and control participants were comparable on general recognition performance. As regards AD patients, they were impaired relative to both aMCI and healthy elders. When assessing Remember and Know responses the aMCI group showed diminished sensitivity for Remember responses but intact Know responses compared to healthy elders. In contrast, AD patients showed decreased sensitivity for both Remember and Know responses compared to control and aMCI participants. The response bias index revealed that AD patients were more liberal than aMCI and control participants when providing Know responses. On the other measures, response bias was comparable between the groups. Overall, this study indicates that the R/K procedure can characterize different aspects of recognition memory performance in persons with aMCI or AD.     

Experiences and Decisions that Motivate Women at Increased Risk of Breast Cancer to Participate in an Experimental Screening Program

Although the discovery of mutations on BRCA1 and BRCA2 genes associated with high breast cancer risk has given rise to screening and surveillance initiatives, there is little documentation on why high-risk women choose to enter screening programs. The objective of this qualitative study was to develop a detailed understanding of the experiences and decisions that motivate women with increased risk of hereditary breast cancer to participate in the multicentered Quebec experimental breast screening program. Our study involved 21 participants who were either BRCA carriers or at risk and untested. These women were interviewed while participating in the screening program. Our study demonstrates that intensive screening programs may provide valuable reassurance for women with increased familial risk of hereditary breast cancer, who count on early detection and rapid response from professionals if and when a problem arises. Health professionals must take these and others concerns into account to ensure their interventions are most consistent with women’s needs.     

Scientific, political, ethical, or pragmatic issues in the collection of ethnic statistics: an exploratory survey in public institutions in Montréal

In recent years, ethnic statistics have been at the core of a passionate debate in many Europeans countries. This debate has been as much about the political legitimacy of ethnoracial data collection in the census as it has been about the scientific legitimacy of ethnic statistics to understand social inequality and discrimination. These questions have not provoked the same kind of intense debate among academics in Canada. However, very few studies have examined the relevance of these issues beyond the census. This paper presents results of an exploratory study conducted with 14 major public institutions across diverse sectors including health, law enforcement and public safety, social services, and housing in Montréal. Investigating which institutions collects ethnic statistics and why, the study examined the political, scientific, ethical, and pragmatic issues raised by local managers.     

Testing the representation of time in reference memory in the bisection and the generalization task: the utility of a developmental approach

This study examined the effect of the variability of representation of durations in reference memory on temporal discrimination performance in children aged 5 and 8 years as well as in adults using a bisection (Experiment 1) and a generalization task (Experiment 2). In each task, the participants were familiarized before the blocks of tested trials with either the same referent duration values (fixed condition) or a distribution of referent duration values, with a mean equal to the referent durations used in the fixed condition and a .20 coefficient of variation (variable condition). The results showed that the sensitivity to duration was lower in the variable than in the fixed condition in the children and, to a lesser extent, in the adults. The modelling of the data indicated that this effect was due to the increase in the variability of the representation of durations in reference memory, but also to changes in the decisional processes.