Plasma BDNF is reduced among middle-aged and elderly women with impaired insulin function: Evidence of a compensatory mechanism

Brain-derived neurotrophic factor (BDNF) plays a regulatory role in neuronal differentiation and synaptic plasticity and has been linked to glucose regulation and cognition. Associations among plasma BDNF, cognition, and insulin function were explored. Forty-one participants with impaired insulin function (IIF), ranging from insulin resistance to type 2 diabetes mellitus (T2DM), were matched with 41 healthy controls on gender, age, education, and IQ. Participants received complete medical, neurological, psychiatric, and neuropsychological evaluations. IIF individuals had significantly lower plasma BDNF levels than controls, particularly females, and higher BDNF levels were associated with poorer explicit memory in IIF females, suggesting that higher levels within this group may reflect the body’s efforts to respond to damage. After accounting for age, education, and HbA1c, BDNF significantly predicted 13.1–23.5% of the variance in explicit memory in IIF women. These findings suggest that BDNF elevations within diseased groups may not always be a marker of health.     

Neurofunctional correlates of personality traits in relapsing-remitting multiple sclerosis: An fMRI study

Extraversion and Neuroticism are two fundamental dimensions of human personality that influence cognitive functioning in healthy subjects. Little is known about personality changes that may occur in patients with multiple sclerosis (MS) nor about, in particular, their neurofunctional basis. The aim of this study is to determine the impact of personality characteristics on brain activity in patients with MS. Eighteen patients with clinically definite relapsing-remitting MS without any evidence of psychiatric or cognitive disorders and thirteen healthy controls matched for age, gender and education were investigated using functional magnetic resonance imaging (fMRI) during the execution of an “n-back” task. No differences were detected on the behavioral tests between the two groups, although the MS patients had lower total IQ and showed a trend towards higher Extraversion and Neuroticism scores than did the controls. fMRI analyses demonstrated that Extraversion scores were positively associated with brain activity in the fronto-parietal network including the superior parietal lobule and dorsolateral prefrontal cortex in both groups during the high load condition of the n-back task. Given the overlapping neural systems found in the two groups, we suggest that the neural activity associated with specific personality dimension is a neurophysiological characteristic preserved in patients with MS at an early stage in the course of their disease.     

Explaining Consumer Conduct: From Planned to Self‐Expressive Behavior1

Within mainstream social psychology, consumer behavior has been explained mainly in terms of the theory of planned behavior (TPB). Recently, some authors suggested that self‐identity dimensions can explain different types of intentions. To compare the predictive power of a tentative new model of self‐expressive consumer behavior with that of the TPB, three studies were conducted in which, besides the classical variables of the model of TPB, variables concerning self‐identity were also taken into account. Three independent samples (N₁= 257, N₂= 214, N₃= 298) were recruited to study the intention to buy fashionable watches, trendy backpacks, and cellular telephones in relation to the aforementioned variables derived from TPB and from identity theory. Data analyses, based on structural equation modeling, show that identity variables contribute significantly to the explanation of purchase intention.     

The Measuring and Observation Tool in Sports

The Measuring and Observation Tool in Sports (MOTS) has been designed to facilitate the systematic observation of sports. It is a user-friendly tool developed to help researchers observe, codify, register, and analyze any situation that occurs in a natural or habitual context in which behaviors are spontaneous. Users can define up to 12 mutually exclusive code sets and up to 120 different behaviors to facilitate data collection and can work with any observational data type: event sequences, event sequences over time, state sequences, interval sequences, or multievent sequences. MOTS plays digital video files, which allows for video and taxonomic tools to be displayed on the screen at the same time. The observations are registered automatically, including the time and duration of the event, in frames and seconds simultaneously. Furthermore, the data analysis feature allows the user to calculate the percentage of intervals, the frequency distributions, and the conditional probabilities.     

Self-regulated profiles and academic achievement

To date, research on the relation between learning self-regulation and academic achievement has generally show disparate results. This work intends to look into this relation from a new perspective, which consists in classifying the students as more or less self-regulated depending on diverse indicators and using cluster analysis. The aim of this work was to identify the possible self-regulated learning profiles in a sample of university students. By means of stepwise linear regression analysis, we determined which of the selected variables better predicted metacognitive self-regulation. Then, three significantly different self-regulated learning profiles were obtained by two-step cluster analysis with those variables. Lastly, ANOVA was used to analyse the relation between the self-regulated learning profiles and academic achievement. The implications of these data for the educational practice at university are discussed.     

The freedom from distraction factor in the attention deficit hyperactivity disorder: a short model

Attention deficit hyperactivity disorder (ADHD) usually presents a profile in which the freedom from distraction factor of the WISC-R (FDF) is affected to a greater extent than the verbal comprehension factor (VCF) and the perceptual organisation factor (POF). The formulation FDF< (VCF + POF)/2 has good sensitivity for ADHD. The aim of this study was to reduce the number of tests needed for the formulation FDF< (VCF + POF)/2, maintaining the sensitivity for ADHD and concordance with the complete formulation. A clinical sample of 167 children with ADHD is analysed (6-16 years). The cases of ADHD were defined according to DSM-IV criteria and they were assessed with WISC-R, Child Symptom Inventory and Social and Occupational Activity Assessment Scale. Lineal regression method was used to reduce the number of tests. The results showed that the short formulation reduces the number of tests by half and it has 83% sensitivity for ADHD. This formulation presents a good concordance with the complete version. The FDF is significantly lower than the VCF, POF and intellectual quotient in cases of ADHD. Comorbidity, social or school activity do not have a significant influence on the probability that FDF< (VCF + POF)/2.     

Relationship among values, beliefs, norms and ecological behaviour

The present study focuses mainly on the relationship between psychological constructs and ecological behaviour. Empirical analysis links personal values, ecological beliefs, consequences of environmental conditions, denial of ecological obligation, environmental control, personal norms and environment protection behaviour. Survey data from a path analysis of a Spanish sample of 403 individuals were used, showing that ecological beliefs, personal norms and eco-altruistic values have become the main psychological explanatory variables of environment protective behaviour. Ecological beliefs, when measured by the New Ecological Paradigm Scale, affected ecological behaviour decisively. Environmental and altruistic values were shown to be related to moral obligation, and a basic variable to understand behaviour. Personal norm mediated the effects of values and environmental control on ecological behaviour.     

Cognitive aspects of binge drinking

This paper aims to explore causes of binge drinking in young people and the effects that they seek when they drink alcohol, based on age and alcohol intake. 4,083 questionnaires were administered to 1,361 university students and 2,722 adolescents at their educational institutions. The findings corresponding to those who reported practising binge drinking -2,917 subjects- are presented in the paper. Taking into account the regularity of the practice and the alcohol intake, cluster analysis differentiated two consumer types in each group: the radical type (21.2% university students-18.2% adolescents): 10-11 drinks 3 days a week and for more than 10 months a year; and the average type (78.7% university students-81.7% adolescents): 4-5 drinks twice a week and for 8-9 months. Drinking as a way of having fun (75.2%) and drinking for the sake of drinking (81.9%) are two of the main causes underlying binge drinking, economical reasons being secondary for adolescents As for the expected effects, the short-term positive aspects of moderate consumption (being more talkative, euphoric...) stand out. Adolescents also expect to improve some of their personal skills (more self-confidence...). These results corroborate and increase the information currently available and allow us to propose alternatives adapted to young people's real needs.     

"Seizing and freezing" on a significant-person schema: need for closure and the transference effect in social judgment

Two experimental studies examined the possibility that the need for cognitive closure (NfCC) affects the tendency to exhibit transference effects in social encounters. They reveal that the transference effect is more pronounced when individuals' (dispositional) NfCC is high (vs. low). In Study 1, this effect is demonstrated with respect to the transference of false memories about a newly encountered target person generalized from one's representation of a significant other. In Study 2, it is demonstrated with respect to the transference of both false memories and affective reaction to a new leader based on one's representation of a past leader. The discussion considers the role of motivation in the transference effect in relation to the social cognitive and psychodynamic views of transference.     

A dynamic extraversion model. The brain's response to a single dose of a stimulant drug

The aim of this paper is to present a mathematical dynamic modelling of the effect a stimulant drug has on different people which, at the same time, can be a useful tool for future brain studies. To this end, a dynamic model of the evolution of extraversion (considering its tonic and phasic aspects) has been constructed taking into account the unique personality trait theory and the general modelling methodology. This model consists of a delayed differential equation which, on one hand, considers that the active stimulus, a consequence of a single intake, is not constant; on the other hand, it contemplates that the state variable representing the phasic extraversion also represents the brain activation. The derivative of this state variable is calculated as the sum of the homeostatic control flow, the excitatory effect flow and the inhibitor effect flow. The solutions of this equation relate the tonic activation of an individual (that characterizes his or her personality) with his or her phasic activation level, whose evolution over time describes the organism's response to a single drug intake. These solutions quantitatively reproduce the predictions of current personality theories and anticipate vulnerability to drug misuse and addiction development.