Concerns about breast cancer and relations to psychosocial well-being in a multiethnic sample of early-stage patients.

Much work on psychosocial sequelae of breast cancer has been guided by the assumption that body image and partner reaction issues are focal. In a tri-ethnic sample of 223 women treated for early-stage breast cancer within the prior year, the authors assessed a wider range of concerns and relations to well-being. Strongest concerns were recurrence, pain, death, harm from adjuvant treatment, and bills. Body-image concerns were moderate; concern about rejection was minimal. Younger women had stronger sexual and partner-related concerns than older women. Hispanic women had many stronger concerns and more disruption than other women. Life and pain concerns and sexuality concerns contributed uniquely to predicting emotional and psychosexual disruption; life and pain concerns and rejection concerns contributed to predicting social disruption. In sum, adaptation to breast cancer is a process bearing on several aspects of the patient's life space.     

Utility of the Millon Behavioral Medicine Diagnostic to Predict Medication Adherence in Patients Diagnosed with Heart Failure

Medication non-adherence is common and a primary reason for poor medical outcomes among individuals with heart failure (HF). This study's aims were to determine whether depression, hostility, and the personality-based Millon Behavioral Medicine Diagnostic (MBMD) Medication Abuse scale were associated with medication adherence (e.g., beta-blockers, ACE inhibitors, diuretics, statins) beyond contributions of demographic, medical, and psychosocial variables in an ethnically-diverse sample of 105 men and women diagnosed with HF. In hierarchical regression, greater MBMD Medication Abuse scale scores were associated with poorer adherence above and beyond both depression (β?=?.236, t[102]?=?2.113, p?=?.037) and hostility (β?=?.244, t[102]?=?2.506, p?=?.014). The Medication Abuse scale also completely mediated the relationship between adherence and depression. These findings suggest that personality measures such as the MBMD and hostility scales might be utilized in future studies investigating predictors of adherence and also used clinically to predict medication adherence among HF patients.     

Using the Millon Behavioral Medicine Diagnostic (MBMD) to Evaluate the Need for Mental Health Services in Association with Biomarkers of Disease Status Among HIV Positive Men and Women

Psychological distress states have been related to rate of disease progression among HIV-positive individuals. However, the measures that have been used in this research as well as the treatment context of the populations studied are highly variable, making it challenging for clinicians to incorporate such measures into screening batteries. The present study examined the association of two summary scales of the Millon Behavioral Medicine Diagnostic (MBMD; Millon et al., Millon Behavioral Medicine Diagnostic. NCS Assessments, Minneapolis, 2001), with markers of HIV disease status (CD4 and CD8 cell counts, viral load) among an ethnically diverse sample of 147 HIV-positive individuals (52 men who have sex with men, 34 men who have sex with women, and 51 women) who had recently initiated Highly Active Antiretroviral Therapy (HAART). After controlling for age and months since HIV diagnosis, we found that higher scores on the overall MBMD Psych Referral Summary Scale, reflecting a need for mental health treatment, were related to greater HIV viral load but did not relate to CD4 or CD8 cell counts. Subgroup analyses revealed that Psych Referral scores were related to greater HIV viral load only for the men who have sex with men (MSM) subgroup. These results suggest that the MBMD may help in identifying psychosocial characteristics associated with some markers of disease status in persons with HIV and perhaps may also be useful in identifying individual differences in response to treatment and eventual disease outcome.     

Choosing among techniques for quantifying single-case intervention effectiveness

If single-case experimental designs are to be used to establish guidelines for evidence-based interventions in clinical and educational settings, numerical values that reflect treatment effect sizes are required. The present study compares four recently developed procedures for quantifying the magnitude of intervention effect using data with known characteristics. Monte Carlo methods were used to generate AB designs data with potential confounding variables (serial dependence, linear and curvilinear trend, and heteroscedasticity between phases) and two types of treatment effect (level and slope change). The results suggest that data features are important for choosing the appropriate procedure and, thus, inspecting the graphed data visually is a necessary initial stage. In the presence of serial dependence or a change in data variability, the nonoverlap of all pairs (NAP) and the slope and level change (SLC) were the only techniques of the four examined that performed adequately. Introducing a data correction step in NAP renders it unaffected by linear trend, as is also the case for the percentage of nonoverlapping corrected data and SLC. The performance of these techniques indicates that professionals' judgments concerning treatment effectiveness can be readily complemented by both visual and statistical analyses. A flowchart to guide selection of techniques according to the data characteristics identified by visual inspection is provided.     

Evidence of recursion in tool use

We discuss the discovery of technologies involving knotted netting, such as textiles, basketry, and cordage, in the Upper Paleolithic. This evidence, in our view, suggests a new way of connecting toolmaking and syntactic structure in human evolution, because these technologies already exhibit an "infinite use of finite means," which we take to constitute the key transition to human cognition.     

Stem allomorphy in the Spanish mental lexicon: evidence from behavioral and ERP experiments

This study presents results from a nonce-word elicited production task and a reading experiment using event-related brain potentials (ERPs) investigating finite forms of Spanish verbs which consist of marked stems and regular person and number agreement suffixes. The first experiment showed that unmarked stems are productively extended to nonce words, whereas marked stems generalize more restrictively to nonce words, based on lexical similarity to existing stem forms. The second experiment yielded a lexical ERP signature for stem violations and an ERP pattern signaling morpho-syntactic (rule-based) processing for suffix violations. We argue that stem allomorphy is lexically represented in the Spanish mental lexicon, with marked stems forming subnodes of structured lexical entries.     

Psychosocial Factors and Disease Progression in Cancer

ABSTRACT— Psychosocial factors such as stress, personality, and social support relate to differences in disease progression in cancer patients. Neuroendocrine substances associated with psychosocial factors may regulate immune responses to cancer, as well as regulate the activity of oncogenic (cancer-causing) viruses, DNA-repair processes, and the expression in tumor cells of genes that may affect the tumor's growth and metastasis. Biobehavioral oncology research seeks to understand how these psychosocial factors, and interventions designed to modify them, become neurohormonal changes that alter cell signaling and tumor growth, viral oncogenesis, and immune responses. We review the empirical basis for psychosocial factors and biobehavioral processes in cancer progression and suggest future research.     

Refining personality assessments by combining MCMI high point profiles and MMPI codes. Part II. MMPI code 27/72

The relationship between the MMPI 27/72 code type and MCMI high point codes is examined for 228 psychiatric patients. MCMI high point codes that correspond highly with MMPI 27/72 code enable the clinician to identify three discrete personality subgroups entitled: Fearfully Dependent, Conforming-Dependent, and Ambivalently Dependent. The central features of each of these groups are described, and their clinical characteristics used as a basis for differentiating ambiguities and contradictory interpretations commonly given the MMPI 27/72 code type.     

Wajsberg algebras and post algebras

We give a presentation of Post algebras of ordern+1 (n1) asn+1 bounded Wajsberg algebras with an additional constant, and we show that a Wajsberg algebra admits a P-algebra reduct if and only if it isn+1 bounded.This autor is partially supported by Grant PB90-0465-C02-01 of D.G.I.C.Y.T. of SpainPresented byJan Zygmunt