Biomedical enhancement and the pursuit of mastery and perfection: a critique of the views of Michael Sandel

This article is a comprehensive critical analysis of the objections of Michael Sandel to the possibilities of human enhancement as foreseen by recent developments in new (particularly genetic) biotechnologies. It is shown that enhancement has always been a feature of human development. The nature and possibilities of these new technologies are briefly discussed, followed by an explanation of Sandel's views. In critical response to Sandel, the author raises three arguments that are discussed in detail, followed by a conclusion that contains wrap-up arguments. The three main arguments relate, first, to Sandel's rejection of enhancement tout court, second to the (in)consistency of his argument about the ‘gifted’ nature of reality, and third to the problems raised by his idea that the striving for mastery is the main problem with enhancement. On the basis of an extensive analysis, the author finds Sandel's position untenable. It is shown that Sandel espouses the ‘simple conservative argument’ (Buchanan). The author concludes that science and technology are not value free, and that the critical evaluation of enhancements cannot lead to an overall judgment, but has to progress in a piecemeal manner. The author also concludes that the notion of ‘human nature’ cannot be regarded as a moral desideratum.     

Responsivity to stress in chronic posttraumatic stress disorder due to childhood sexual abuse

The purpose of this study was to investigate psychological, cardiovascular, and neuroendocrine reactivity to standardized stress tests (orthostatic challenge, Stroop Color Word Test) in drug-free adult women with chronic PTSD due to repetitive childhood sexual abuse. At baseline, the 11 patients showed significantly higher mean scores on the Symptom Check List-90 and the Profile of Mood States than 13 healthy female controls, whereas baseline cardiovascular or hormonal parameters showed no differences between the groups. Also, no significant differences were found between the two groups in cardiovascular and hormonal responsivity to the stress tests. Thus, in the presence of robust psychological differences, the patients with chronic PTSD due to childhood sexual abuse did not show alterations in baseline values of neurobiological parameters, nor did they react differently to a physical and mental stress test when compared to healthy controls.     

Nociceptive sensitivity and control: hypo- and hyperalgesia under two different modes of coping

Effects of perceived control on nociceptive sensitivity were investigated in an experimental arrangement with N = 40 healthy volunteers in which the duration of painful pressure stimuli was made contingent on success in a tracking task. Perceived control over the pain duration was manipulated through varying the frequency of success in the tracking task. The amount of painful stimulation applied in the high and low control conditions was balanced by a yoked-control design. Pain sensitivity was measured before and after the tracking task by means of a thermal sensory analyzer. Pain sensitivity was found to decrease in the low control condition (hypoalgesia), and to increase slightly in the high control condition (hyperalgesia). These effects are explained with reference to a dual process model of coping.     

On the inhomogeneity of a test compounded of two Rasch homogeneous subscales

Van den Wollenberg stated a theorem specifying the conditions for a test, which is composed of two Rasch homogeneous subscales, as also behaving Rasch homogeneously. In our note, simple numerical counterexamples are given for which this theorem fails.While preparing the final version of this note, Ilse Rop passed away. The first author therefore takes sole responsibility for this final version.     

Review Essay

Studies in East European Thought -