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Eric T. Poehlman, Ph.D., was an internationally recognized, tenured professor at the University of Vermont (UVM) in Burlington
when, in October 2000, a junior member of Poehlman’s laboratory became convinced that he had altered data from a study on
aging volunteers from the Burlington area. This suspicion developed into one of the most significant cases of scientific misconduct
in the history of the US Department of Health and Human Services’ (HHS) Office of Research Integrity (ORI), launching a US
Department of Justice (DOJ) civil and criminal fraud investigation and, eventually, to a much publicized guilty plea and felony
conviction. In the end, Dr. Poehlman admitted to 54 findings of scientific misconduct made by the UVM and ORI, agreed to retract
or correct ten of his publications and to exclude himself from federal procurement and nonprocurement transactions for life.
The United States Government’s handling of this case was distinguished by a highly cooperative approach that integrated the
resources of the US Attorney’s Office for the District of Vermont (USAO) and both ORI and the Office of the Inspector General
(OIG) in HHS in the common goal of prosecuting research fraud.
The content of this article represents the personal views of the authors and does not express the opinion or policy of DHHS
or its components.
A paper on this topic was presented at the 6th International Bioethics Conference on the subject of ‘The Responsible Conduct
of Basic and Clinical Research’, held in Warsaw, Poland, 3–4 June 2005. 相似文献
64.
Bryant's Empathy Index for children and adolescents: psychometric properties in the Spanish language
The present study investigated the following issues: (1) the structure of Bryant's Empathy Index for children and adolescents in a Spanish sample of 408 boys and 424 girls (M age=14.4 yr.), and (2) sex differences, including effect sizes and internal consistency of the scale. A principal components factor analysis with oblimin rotation showed that 20 of the index's 22 items load on three robust factors, related to Feelings of Sadness, Understanding Feelings, and Tearful Reaction with regard to the emotions of others. The 3-factor structure obtained an adequate fit to the data in the confirmatory factor analysis. Coefficients alpha ranged between .72 and .78. The 3 factors accounted for 42% of variance. As expected, girls scored higher than boys. It was concluded that the Spanish version of Bryant's Empathy Index has an acceptable reliability and construct validity, making it useful for research. 相似文献
65.
Kris AO 《Journal of the American Psychoanalytic Association》2005,53(1):7-22
Why are we susceptible to hypocrisy? Four preconditions for falling prey to hypocrisy are delineated. The reasons for our complex attitude to hypocrisy, both condoning and condemning it, are also explored. Hypocrisy is the false claim to virtue. It always refers to consciously intended deception by a person in a position of trust. Making use of literary examples, the investigation starts with the delineation of three readily apparent preconditions for falling prey to hypocrisy. Idealization of the hypocrite is seen as a defense against a dread of uncertainty on the part of the person who succumbs to hypocrisy. The addition of a third precondition, the force of powerful desire, completes the introduction. A selective review of historical and philosophical studies of hypocrisy over the past twenty-five hundred years situates the problem of the susceptibility to hypocrisy. Application of psychoanalytic formulations and clinical data, principally from the study of patients whose psychoanalysts committed ethical violations, produces a fourth precondition for succumbing to hypocrisy: transference, with a regression from mature trust to a condition of unmodified basic trust. 相似文献
66.
Promoting and protecting youth mental health through evidence-based prevention and treatment 总被引:1,自引:0,他引:1
For decades, empirically tested youth interventions have prevented dysfunction by addressing risk and ameliorated dysfunction through treatment. The authors propose linking prevention and treatment within an integrated model. The model suggests a research agenda: Identify effective programs for a broadened array of problems and disorders, examine ethnicity and culture in relation to intervention adoption and impact, clarify conditions under which programs do and do not work, identify change mechanisms that account for effects, test interventions in real-world contexts, and make tested interventions accessible and effective in community and practice settings. Connecting the science and practice of prevention and treatment will be good for science, for practice, and for children, adolescents, and their families. 相似文献
67.
Anton Kühberger Michael Schulte-Mecklenbeck Josef Perner 《Organizational behavior and human decision processes》1999,78(3):248
A meta-analysis of Asian-disease-like studies is presented to identify the factors which determine risk preference. First the confoundings between probability levels, payoffs, and framing conditions are clarified in a task analysis. Then the role of framing, reflection, probability, type, and size of payoff is evaluated in a meta-analysis. It is shown that bidirectional framing effects exist for gains and for losses. Presenting outcomes as gains tends to induce risk aversion, while presenting outcomes as losses tends to induce risk seeking. Risk preference is also shown to depend on the size of the payoffs, on the probability levels, and on the type of good at stake (money/property vs human lives). In general, higher payoffs lead to increasing risk aversion. Higher probabilities lead to increasing risk aversion for gains and to increasing risk seeking for losses. These findings are confirmed by a subsequent empirical test. Shortcomings of existing formal theories, such as prospect theory, cumulative prospect theory, venture theory, and Markowitz's utility theory, are identified. It is shown that it is not probabilities or payoffs, but the framing condition, which explains most variance. These findings are interpreted as showing that no linear combination of formally relevant predictors is sufficient to capture the essence of the framing phenomenon. 相似文献
68.
In this contribution, the author analyzes Vladimir Solov'ëv's intention to study the idea of the Good as something relatively independent from religion and metaphysics. Some implications of Solov'ëv's definition of moral philosophy in The Justification of the Good are investigated, and illustrated with his applied ethics of war in chapter 18 of this book. It appears that Solov'ëv's moral philosophy and his account of war must be understood in connection with the central place of the cult of ancestors in his ethics. The idea of the Good and the idea of God spring from a religious origin and appear in our efforts to conjure up and exorcize the spirits of our forefathers. The author explains this ethics by referring to Solov'ëv's article China and Europe. There, Solov'ëv assumes that the Christian mind is treatened by the danger of a cultural order in which the cult of ancestors is most purely preserved. In the future war against China, however, Christian civilization must show itself superior to its enemy without betraying its loyalty to its own ancestors. The author concludes that in Solov'ëv's ethics, the moral subject is divided between the confirmation of its own autonomy and its being haunted by the spirits of its forefathers, a haunt which results in relentless wars against others 相似文献
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Psychiatric services provided to Native Americans should be culturally relevant and integrated with the values and beliefs of the culture since Native Americans use Western health care as a last resort. Reduced utilization of services may be the result of cultural beliefs that sickness or illness comes from disharmony with oneself, one's community, and nature. Treatment entails resolving the disharmony and restoring a state of balance and integration. Western psychiatric services have not usually provided active psychiatric treatment, while simultaneously encouraging participation in native ceremonies and traditions of healing. For 3 years, the Wyoming State Hospital has offered Sweat Lodge ceremonies administered by the Wind River Reservation as part of a pattern of working together to improve the care of Native Americans admitted to the facility. Results indicate increased utilization of hospital services as well as increased patient and tribal satisfaction, improved health care outcomes, and reduced length of stay. This report argues that culturally specific and sensitive treatment interventions provide a concrete and specific benefit to the population which is targeted. 相似文献