Time-stamping computer events to report .1-msec accuracy of events in the Micro Experimental Laboratory

A critical problem in most real-time programming tasks is the verification that timing of the presented displays and recorded events occur at the expected times. It is often difficult for psychologists to verify critical timing because of the lack of costly specialized tools and technicians to measure events with millisecond accuracy. Algorithms utilized in a new Time Audit mechanism, added to the Micro Experimental Laboratory, are described. This new mechanism involves the recording and time stamping of all input and output events with 0.1-msec accuracy. This allows the experimenter to determine the initiation, duration, and termination of each event and also makes it possible to relate these events to the synchronization of the screen refresh cycle. A customized user interface provides a time log and event-tracing feature that enables nonprogrammers to determine the duration of command execution to the .1-msec level, allowing rapid, precise assessment of program execution. The resulting time log provides a detailed specification of the experimental events for debugging and a permanent record of the experimental procedure.     

Glucose and physostigmine effects on morphine- and amphetamine-induced increases in locomotor activity in mice

Recent findings indicate that glucose antagonizes several behavioral effects of cholinergic antagonists and augments those of cholinergic agonists. For example, scopolamine elicits increased locomotor activity, an action which is attenuated by glucose and by combined treatment with glucose and physostigmine at doses which are individually without effect. Opiate and catecholamine agonists, such as morphine and amphetamine, also elicit hyperactivity. The present study examined interactions of glucose and physostigmine with morphine- and amphetamine-induced hyperactivity. Mice received saline, morphine (10 mg/kg), or amphetamine (1 mg/kg) 50 min prior to testing, followed by saline, physostigmine (0.01, 0.05, 0.1, or 0.2 mg/kg), or glucose (10, 50, 100, or 500 mg/kg) administered 20 min prior to activity testing in an open field. Physostigmine significantly attenuated both morphine- and amphetamine-induced increases in activity, but higher doses were required to attenuate the effects of amphetamine. Like physostigmine, glucose significantly attenuated morphine-induced activity levels, but unlike physostigmine, glucose did not attenuate amphetamine-induced activity. Thus, the behavioral effects of morphine were more susceptible to modification by physostigmine and glucose than were the effects of amphetamine. The attenuation of morphine-induced hyperactivity demonstrates a similarity between glucose and cholinergic agonists, and also indicates that glucose may inhibit, directly or indirectly, opiate functions. More generally, these findings add to the evidence that circulating glucose levels selectively influence a growing list of behavioral and neurobiological functions.     

Visual and tactile memory for 2-D patterns: Effects of changes in size and left-right orientation

Visual identification of 3-D objects depends on representations that are invariant across changes in size and left-right orientation. We examined whether this finding reflects the unique demands of processing 3-D objects, or whether it generalizes to 2-D patterns and to the tactile modality. Our findings suggest that object representation for identification is influenced greatly by the processing demands of stimulus materials (e.g., 2-D vs. 3-D objects) and stimulus modality (touch vs. vision). Identification of 2-D patterns in vision is adversely affected by left-right orientation changes, but not size changes. Identification of the same patterns in touch is adversely affected by both changes. Together, the results suggest that the unique processing demands of stimulus materials and modality shape the representation of objects in memory.     

Religious Coping and Heart Transplantation: From Threat to Health

Previous research has established the existence of homogeneous religious coping profiles in cardiac-transplantation candidates labeled as the deferring/collaborators, self-directors, and the eclectic religious copers. However, their prospective impact on outcome has not yet been established. This paper examines potential differences between pre-cardiac transplantation religious coping cluster groups on post-cardiac transplantation quality of life (physical functioning, mental health, and general health). Results indicated that the religious coping profiles of deferring/collaborators and self-directors had significantly better scores on mental health and general health than did the eclectics. Implications for religious-coping research and clinical practice are discussed.     

Two Types of Externalism

A contrast is drawn between two types of externalism, one based on ideas of Wittgenstein, the other on arguments from Putnam. Gregory McCulloch's attempt to combine the two types is then examined and criticized. Putnamian externalism is ambiguous. It can be interpreted either as the empirical claim that we give priority to scientific as opposed to other forms of discourse, or as a metaphysical claim that our language attempts to conform to the structure of the world 'in itself'. But the first claim is simply false, and the second involves a form of metaphysical realism that a Wittgensteinian must reject as unintelligible. McCulloch's attempted synthesis of the two types is therefore either incoherent, or else simply adds an empirical falsehood to Wittgenstein's conceptual point. It is also noted that Putnam himself has progressively retreated from his original claims, and now appears to be a Wittgensteinian, but not a 'Putnamian', externalist.     

Should the behavioral sciences become more pragmatic? The case for functional contextualism in research on human behavior

Although societal need for behavioral science research is enormous, current research practices seem to be inefficient vehicles for producing knowledge that guides practical action. Many of our most popular theories provide little direct guidance for application. They focus on the development of models of the relationships among organismic events such as attitudes, self-efficacy expectations, and behavior, but pay little or no attention to the contextual influences on behavior. Such research is in keeping with a long-standing mechanistic tradition in psychology. We propose a version of contextualism as an alternative paradigm for the behavioral sciences. According to this paradigm, theories and research are evaluated in terms of their contribution to the prediction and influence of behavior. Basic research organized to pursue this goal has a direct bearing on how behavioral phenomena can be changed for practical purposes. Conversely, applied research contributes to basic understanding of the determinants of psychological phenomena.     

An affordable computer-aided method for conducting Morris water maze testing

A relatively inexpensive and reliable computer-aided method for assessing Morris water maze performance is described. The procedure uses SigmaScan digitizing software (Jandel Scientific, San Rafael, CA) to collect distance swum data, while escape latencies are measured with a hand-held stopwatch. Swim paths are videotaped for subsequent viewing and saved on disk as data sets ofx,y coordinates. At a later time,x,y data files are printed and analyzed to obtain additional performance measures (e.g., distance swum in previous reinforced quadrant, heading angle, etc.). Intra- and interrater reliabilities associated with this method are presented. Correlation coefficients in ther = .85?.90 and above range are reported for both reliability types. Given its approximate cost of $1,500 (excluding the price of an IBM-compatible computer), the present procedure potentially can aid in performing instructional and research activities at small colleges which typically lack extensive equipment budgets.