Transfer of spatial behavior between different environments: implications for theories of spatial learning and for the role of the hippocampus in spatial learning

In 3 experiments, rats were required to find a submerged platform located in 1 corner of an arena that had 2 long and 2 short sides; they were then trained to find the platform in a new arena that also had 2 long and 2 short sides but a different overall shape. The platform in the new arena was easier to find if it was in a corner that was geometrically equivalent, rather than the mirror image, of the corner where it had previously been located. The final experiment revealed that hippocampal lesions impaired rats' ability to find the platform in these arenas. The results suggest that rats did not use the overall shape of the arena to locate the platform but relied on more local cues and that the hippocampus plays a role in navigation based on these cues.     

Prepared movements are elicited early by startle

A startle stimulus has been shown to elicit a ballistic response in a reaction time (RT) task at very short latencies without involvement of the cerebral cortex (J. Valls-Sole, J. C. Rothwell, F. Gooulard, G. Cossu, & E. Munoz, 1999). The present authors examined the nature of the startle response. A simple RT task was used in which 8 participants performed arm extension movements to 3 target distances (20 degrees, 40 degrees, and 60 degrees ) in a blocked design. An unpredictable startling acoustic stimulus (124 dB) replaced the imperative stimulus in certain trials. The authors verified the presence of a startle response independent from the prepared response by observing electromyographic (EMG) activity in sternocleidomastoid and orbicularis oculi muscles. Findings indicated that when the participant was startled, the intended voluntary response was produced at significantly shorter response latencies. Furthermore, the kinematic variables of the observed response during startle trials for all 3 target distances were mostly unchanged. The EMG characteristics of the responses were not modified, indicating that the response produced was indeed the prepared and intended response.     

How lonely are gay and lesbian youth?

UCLA Loneliness Scale (8-item version) scores in a sample of 384 gay and lesbian adolescents support the hypothesis that such youths are especially vulnerable to loneliness.     

Affective, behavioral, and cognitive functioning in adolescents with multiple suicide attempts

The purpose of this study was to examine affective, behavioral, and cognitive functioning in adolescents with multiple suicide attempts. Forty-seven adolescents with a history of multiple suicide attempts (MA) were compared to 74 single suicide attempters (SA) on psychiatric diagnosis, depressive symptoms, affect regulation, self-mutilation, alcohol use, and hopelessness. Results revealed that the MA group was more likely to be diagnosed with a mood disorder, and reported more severe depressive symptoms and anger, in comparison to the SA group. Behaviorally, the MA group had higher rates of disruptive behavior disorders and higher levels of affect dysregulation and serious self-mutilation than the SA group. Further, greater levels of hopelessness were reported by the MA than the SA group. After controlling for a mood disorder diagnosis, only differences in anger, affect dysregulation, and serious self-mutilation remained significant. Overall, results suggest that treatment with adolescent suicide attempters might specifically target anger and affect dysregulation to reduce risk for future suicidal behavior.     

The ‘redefinition of death’ debate: Western concepts and western bioethics

Biomedicine is a global enterprise constructed upon the belief in the universality of scientific truths. However, despite huge scientific advances over recent decades it has not been able to formulate a specific and universal definition of death: In fact, in its attempt to redefine death, the concept of death appears to have become immersed in ever increasing vagueness and ambiguity. Even more worrisome is that bioethics, in the form of principlism, is also endeavouring to become a global enterprise by claiming neutrality. It appears that the discourse within both disciplines have similarly manipulated the boundaries of death to include the “dying”. This paper argues that the redefinition of death debate in biomedicine reveals a concept of personhood which is profoundly western in origin and which is in accordance to the concept adhered to within principlism. Biomedicine and bioethics do not appear to acknowledge the limitations of their own world view and hence lack an understanding of their applicability and appropriateness in diverse social and cultural contexts; a situation which adds credence to claims as to the hegemonic and imperialistic nature of all such global enterprises. Ms. Jones is an intensive care clinical nursing specialist. Dr. Kessel is a public health physician and medical ethicist.     

Prolegomena to a Catholic Theology of God between Heidegger and Postmodernity

New opportunities for discourse about God have arisen, along with new challenges to the mainstream Catholic theology of God. In order to take advantage of these opportunities, a truly contemporary Catholic theology of God must critically appropriate three 'events' which have affected its approach to the subject matter: (1) Heidegger's periodizing critique of ontotheology; (2) the 'contemporary' viewed as the arena of contention between modern and postmodern claims; (3) the presence of the Kingdom of God and the revelation of the nature of God in the person and work of Jesus Christ, which alter our understandings of time and being. The present essay sketches a program for an authentically Catholic response to the issues raised by these occurrences, emphasizing the Catholic commitment to incarnation and sacramentality and the necessary effort to retrieve redemptive images of God from modernity, despite the present tendency of some postmodern theologians and philosophers to dismiss aspects of the past as unusable.     

Physical Continuity, Self and the Future

Jeff McMahan's impressive recent defence of the embodied mind theory of personal identity in his highly acclaimed work The Ethics of Killing has undoubtedly reawakened belief that physical continuity is a necessary component of the relation that matters in our self-interested concern for the future. My aim in this paper is to resist this belief in a somewhat roundabout way. I want to address this belief in a somewhat roundabout way by revisiting a classic defence of the belief that enormous changes in the contents of a person's psychology does not preclude justified fear of future pain. I have in mind Bernard Williams' The Self and the Future (1970) in which he argues, against the psychological view, that physical continuity is necessary for survival. I examine Williams' second thought experiment which ostensibly supports that intuition and afterwards defend two related claims. First, I argue that a close examination of the second thought experiment reveals that one's prior commitments to a particular criterion of personal identity can influence one's response to that thought experiment. Second, I argue that Williams' second thought experiment is set out in questionbegging terms. I do not claim, however, that the intuition under consideration lacks justification; I only claim that Williams' second thought experiment does not provide the needed support.     

Temporal contiguity and the judgement of causality by human subjects

Three experiments examined the role of the degree of temporal contiguity between an action and an outcome in human causality judgement. In all the experiments subjects were required to perform an action—pressing a key on a computer keyboard—and to judge the extent to which the action caused an outcome on the computer screen to occur. The action and outcome occurred on a free-operant schedule. In the first experiment a 2-sec delay between the action and outcome reduced causality judgements relative to a situation in which there was no delay. In the second experiment judgements in conditions with delays of 0, 4, 8, and 16 sec were compared with judgements in conditions in which the same pattern of outcomes occurred non-contingently with respect to the subjects' responding. In both of these experiments the events were controlled by random ratio schedules, following the procedure of Wasserman, Chatlosh, and Neunaber (1983), in which each condition was divided into 1-sec intervals. In the third experiment judgements in conditions with delays of 0, 2, 4, or 8 sec were compared in a continuous procedure rather than one divided into 1-sec intervals. In all experiments the increasing delays led to progressively lower judgements of causality. The results are related to three accounts of the mechanism underlying human causality judgement and are also compared with results from analogous animal conditioning studies.     

Performance on ratio and interval schedules with matched reinforcement rates

In the first study, rats were trained to pull a chain on a schedule (RPI) that regulates the probability of reinforcement to maintain a constant average reinforcement rate without differentially reinforcing long inter-response times (IRTs). Although the response rate was sensitive to the overall rate of reinforcement, performance was unaffected by variations between 1 and 50 in the IRT memory size used in programming the schedule. In the second study, two groups of animals performed on either a random-interval (RI) schedule or a RPI schedule, with reinforcement rates determined by those generated by a third group performing on a random ratio (RR) 20 schedule. The RI group responded at a lower rate than the RPI group, which, in turn, responded at a lower rate than the RR group, even though the three groups experienced comparable rates of reinforcement. The fact that the RPI group responded at a lower rate than the RR group suggests that the standard response rate difference observed between ratio and interval schedules, which have been matched for reinforcement rate, cannot be attributed solely to the fact that conventional interval schedules differentially reinforce long IRTs.