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51.
In Drosophila, calcium/calmodulin-dependent protein kinase II (CaMKII) activity is crucial in associative courtship conditioning for both memory formation and suppression of courtship during training with a mated female. We have previously shown that increasing levels of constitutively active CaMKII, but not calcium-dependent CaMKII, in a subset of neurons can decrease the initial level of courtship and enhance the rate of suppression of courtship in response to a mated female. In this study, we demonstrate that a subpopulation of noncholinergic, nondopaminergic, non-GABAergic neurons can cause CaMKII-dependent reductions in initial courtship, but only cholinergic neurons enhance training-dependent suppression. These data suggest that processing of pheromonal signals in two subpopulations of neurons, likely antennal lobe projection neurons, is critical for behavioral plasticity. 相似文献
52.
A crucial demand in dual tasks suffering from a capacity limited processing mechanism is task-order scheduling, i.e. the control of the order in which the two component tasks are processed by this limited processing mechanism. The present study aims to test whether the lateral prefrontal cortex (LPFC) is associated with this demand. For this, 15 participants performed a psychological refractory paradigm (PRP) type dual task in an event-related functional magnetic resonance (fMRI) experiment. In detail, two choice reaction tasks, a visual (response with right hand) and an auditory (response with left hand), were presented with a temporal offset of 200 ms, while the participants were required to respond to the tasks in the order of their presentation. Importantly, the presentation order of the tasks changed randomly. Based on previous evidence, we argue that trials in which the present task order changed as compared to the previous trial (different-order trials) impose higher demands on task coordination than same-order trials do. The analyses showed that cortical areas along the posterior part of the left inferior frontal sulcus as well as the right posterior middle frontal gyrus were more strongly activated in different-order than in same-order trials, thus supporting the conclusion that one function of the LPFC for dual-task performance is the temporal coordination of two tasks. Furthermore, it is discussed that the present findings favour the active scheduling over the passive queuing hypothesis of dual-task processing. 相似文献
53.
Between 2000 and 2004, 125 recreational parachuting fatalities were reported in the USA. Each was categorized using a previously reported taxonomy. While patterns of skydiving fatality were largely unchanged since the last such analysis of fatalities from 1993-1999, some variations were noted. As in previous analyses, most of the recent skydiving fatalities were the direct result of human error. Some examples of commonplace human error fatalities were turning low to the ground resulting in a hard landing, accidentally colliding with other skydivers resulting in entangled parachutes, and failure to deploy the reserve parachute correctly in the event of malfunctioning main parachute. 相似文献
54.
Cognitive impairment in multiple sclerosis is an increasingly recognized entity. This article reviews the cognitive impairment of multiple sclerosis, its prevalence, its relationship to different types of multiple sclerosis, and its contribution to long-term functional prognosis. The discussion also focuses on the key elements of cognitive dysfunction in multiple sclerosis which distinguish it from other forms of cognitive impairment. Therapeutic interventions potentially effective for the cognitive impairment of multiple sclerosis are reviewed including the effects of disease modifying therapies and the use of physical and cognitive interventions. 相似文献
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Hayley C. Leonard Annette Karmiloff-Smith Mark H. Johnson 《Journal of experimental child psychology》2010,106(4):193-207
Previous research has suggested that a mid-band of spatial frequencies is critical to face recognition in adults, but few studies have explored the development of this bias in children. We present a paradigm adapted from the adult literature to test spatial frequency biases throughout development. Faces were presented on a screen with particular spatial frequencies blocked out by noise masks. A mid-band bias was found in adults and 9- and 10-year-olds for upright faces but not for inverted faces, suggesting a face-sensitive effect. However, 7- and 8-year-olds did not demonstrate the mid-band bias for upright faces but rather processed upright and inverted faces similarly. This suggests that specialization toward the mid-band for upright face recognition develops gradually during childhood and may relate to an advanced level of face expertise. 相似文献
57.
ABSTRACTFlashbulb memories are vivid, confidently held, long-lasting memories for the personal circumstances of learning about an important event. Importance is determined, in part, by social group membership. Events that are relevant to one’s social group, and furthermore, are congruent with the prior beliefs of that group, should be more likely to be retained as flashbulb memories. The Fukushima nuclear disaster was relevant to ongoing political conversations in both Germany and the Netherlands, but, while the disaster was congruent with German beliefs about the dangers of nuclear energy, it was incongruent with Dutch support for nuclear power. Danish participants would not have found the disaster to be particularly relevant. Partially consistent with this prediction, across two samples (N?=?265 and N?=?518), German participants were most likely to have flashbulb memories for the Fukushima disaster. Furthermore, event features thought to be related to flashbulb memory formation (e.g. ratings of importance and consequentiality) also differed as a function of nationality. Spontaneously generated flashbulb memories for events other than Fukushima also suggested that participants reported events that were relevant to national identity (e.g. the Munich attacks for Germans, the Utøya massacre for Danes, and Malaysian Airlines flight MH-17 for Dutch participants). 相似文献
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59.
Fifty-seven female netballers completed a training history profile to examine whether the achievement of performance milestones and/or accumulation of sport-specific practice were indicative of an athlete's level of expertise. Similar to previous research, results revealed that expert and developmental athletes accumulated a greater number of hours in netball-specific practice relative to the recreational participants, but did not differ in the number of sports played or hours accumulated in non-netball specific practice. Interestingly, some performance milestones were achieved by the expert and developmental athletes earlier than the recreational participants, however, the developmental athletes achieved a number of milestones at an earlier age than the experts. These findings are discussed in relation to contemporary models of skill development, namely deliberate practice (Ericsson, Krampe, & Tesch-Römer, 1993) and the developmental model of sport participation (Côté, 1999) and the underpinning socio-environmental factors that may influence sport participation and subsequent development of expertise. 相似文献
60.
Striving toward goals is associated with higher levels of subjective well‐being; however, many potential roadblocks to goal achievement exist. The current study extends the understanding of goal regulation processes in its examination of the relationships between dispositional and situational goal adjustment to a profound stressor and their associations with psychological adjustment. Women (N = 103; M age = 57.2 years; 82% Caucasian) with metastatic breast cancer completed semistructured interviews and self‐report measures at study entry and 3 months later. Measures of dispositional and situational goal reengagement were significantly correlated, but dispositional and situational goal disengagement were unrelated. Greater dispositional and situational goal disengagement abilities were associated with fewer cancer‐related intrusive thoughts at Time 1. Dispositional and situational reengagement were positively associated with life satisfaction and sense of purpose and negatively associated with depressive symptoms at Time 1. However, greater initial situational goal disengagement predicted an increase in depressive symptoms over time. Both how an individual typically responds to goal blockage, as well as how an individual is currently responding to a specific blocked goal, appear related to psychological adjustment. 相似文献