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181.
Childhood poverty is linked to a host of physical and psychological disorders during childhood and later in life. In the study reported here, we showed that the proportion of childhood spent in poverty from birth to age 9 was linked to elevated allostatic load, a marker of chronic physiological stress, in 17-year-olds. Furthermore, this prospective longitudinal relationship was mediated by cumulative risk exposure at age 13. The greater the duration of early life spent in poverty, the greater the exposure to cumulative risk. This, in turn, leads to elevated allostatic load. Multiple psychological, biological, and neurological pathways likely account for the social patterning of psychological and physical disease. 相似文献
182.
Sandström A Säll R Peterson J Salami A Larsson A Olsson T Nyberg L 《Stress (Amsterdam, Netherlands)》2012,15(5):503-513
Deficits in executive functioning and working memory associated with frontal lobe dysfunction are prominent in depression and work-related long-term sick leave (LTSL). This study used functional magnetic resonance imaging (fMRI) to investigate potential differences in brain activation patterns in these conditions. In addition, the function of the hypothalamic-pituitary-adrenal (HPA) axis was examined and compared between groups. Since there is a clear overrepresentation of women in these diagnostic groups, and to ensure a more homogenous sample population, only women were included. To examine the neural correlates of relevant cognitive processes in patients on sick leave >90 days due to work-related LTSL, recently diagnosed patients with major depression Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV criteria, untreated), and healthy controls (n?=?10, each group), a 2-back working memory task and a visual long-term memory task were administered during fMRI scanning. HPA axis functioning was investigated using a diurnal curve of saliva cortisol and a dexamethasone suppression test. Task performance was comparable among the three groups. Multivariate image analysis revealed that both memory tasks engaged a similar brain network in all three groups, including the prefrontal and parietal cortex. During the 2-back task, LTSL patients had significant frontal hypoactivation compared to controls and patients with depression. Saliva cortisol measurements showed a flattening of the diurnal rythmicity in LTSL patients compared to patients with depression and healthy contols. Taken together, these findings indicate that work stress-related LTSL and major depression are dissociable in terms of frontal activation and diurnal cortisol rhythmicity. 相似文献
183.
Inattentional Blindness (IB) occurs when observers engaged in resource-consuming tasks fail to see unexpected stimuli that appear in their visual field. Eye movements were recorded in a dynamic IB task where participants tracked targets amongst distractors. During the task, an unexpected stimulus crossed the screen for several seconds. Individuals who failed to report the unexpected stimulus were deemed to be IB. Being IB was associated with making more fixations and longer gaze times on distractor stimuli, being less likely to fixate the unexpected stimulus, and having lower working memory capacity than those who were not IB. Noticing the unexpected stimulus was not contingent upon fixating it, suggesting that some individuals processed the unexpected stimulus via covert attention. The findings support earlier research on working memory and IB. In addition, IBs were less efficient attentional allocators than those who were not IB, as reflected in their eye tracking of irrelevant distractors. 相似文献
184.
Igor Linkov Heather Rosoff L James Valverde Matthew E. Bates Benjamin Trump Daniel Friedman Jessie Evans Jeffrey Keisler 《Journal of Multi-Criteria Decision Analysis》2012,19(3-4):155-168
Created by the State Department's Office of the Coordinator for Reconstruction and Stabilization, the Civilian Response Corps (CRC) contains a diverse pool of qualified and ready‐to‐deploy civilian professionals that support conflict prevention and response efforts in countries or regions that are at risk of, are currently in, or are transitioning from conflict or civil strife. As such, it is vital to optimize the CRC's skill groupings to maximize adaptability and responsiveness to highly uncertain and trying political conditions and crises across the globe. The nature of the CRC value proposition is such that determining which skill set compositions deliver the greatest benefit requires a multi‐faceted perspective that looks at a number of attributes and factors, both tangible and intangible. To meet these needs, an organizational decision‐making approach utilizing multi‐criteria decision analysis (MCDA) was applied to ensure that skill‐grouping allocations were determined in a logical and robust manner. The MCDA analysis allowed for a wide range of worldviews and perspectives, drawn from select members of academia and partner agencies of the CRC who provided their expert opinions on the expected demand for skill groupings commonly identified as most necessary in a civilian ‘surge’ capacity. These skills were assessed with reference to a values hierarchy of representative country scenarios, missions and sub‐missions identified by the Office of the Coordinator for Reconstruction and Stabilization. Of particular interest was the use of the MCDA method to prioritize CRC skill groupings and to help inform the Department of State's understanding of the ‘ideal’ proportion and types of civilian skills for inclusion in the CRC. Copyright © 2012 John Wiley & Sons, Ltd. 相似文献
185.
186.
Schwartz LA Kazak AE Derosa BW Hocking MC Hobbie WL Ginsberg JP 《Journal of clinical psychology in medical settings》2012,19(2):138-146
In addition to the potential for ongoing health concerns, adolescent and young adult (AYA) childhood cancer survivors frequently
report posttraumatic stress symptoms (PTSS). The current study examines whether beliefs about health moderate the relationship
between the number of health problems and PTSS 2 months later in 140 survivors. Beliefs, as measured by scales of the Health
Competence Beliefs Inventory (HCBI), negatively related to PTSS while health problems positively related to PTSS. Three scales
of the HCBI-health perceptions, satisfaction with healthcare and cognitive competence—were significant moderators. The relationship
between health problems and PTSS was stronger in the presence of less adaptive beliefs. These beliefs represent potentially
malleable intervention targets for reducing PTSS in childhood cancer survivors. 相似文献
187.
Anne‐Lise Goddings Stephanie Burnett Heyes Geoffrey Bird Russell M. Viner Sarah‐Jayne Blakemore 《Developmental science》2012,15(6):801-811
The social brain undergoes developmental change during adolescence, and pubertal hormones are hypothesized to contribute to this development. We used fMRI to explore how pubertal indicators (salivary concentrations of testosterone, oestradiol and DHEA; pubertal stage; menarcheal status) relate to brain activity during a social emotion task. Forty‐two females aged 11.1 to 13.7 years underwent fMRI scanning while reading scenarios pertaining either to social emotions, which require the representation of another person’s mental states, or to basic emotions, which do not. Pubertal stage and menarcheal status were used to assign girls to early or late puberty groups. Across the entire sample, the contrast between social versus basic emotion resulted in activity within the social brain network, including dorsomedial prefrontal cortex (DMPFC), the posterior superior temporal sulcus, and the anterior temporal cortex (ATC) in both hemispheres. Increased hormone levels (independent of age) were associated with higher left ATC activity during social emotion processing. More advanced age (independent of hormone levels) was associated with lower DMPFC activity during social emotion processing. Our results suggest functionally dissociable effects of pubertal hormones and age on the adolescent social brain. 相似文献
188.
It has been suggested that downward pointing triangles convey negative valence, perhaps because they mimic an underlying primitive feature present in negative facial expressions (Larson, Aronoff, and Stearns, 2007). Here, we test this proposition using a flanker interference paradigm in which participants indicated the valence of a central face target, presented between two adjacent distracters. Experiment 1 showed that, compared with face flankers, downward pointing triangles had little influence on responses to face targets. However, in Experiment 2, when attentional competition was increased between target and flankers, downward pointing triangles slowed responses to positively valenced face targets, and speeded them to negatively valenced targets, consistent with valence-based flanker compatibility effects. These findings provide converging evidence that simple geometric shapes may convey emotional valence. 相似文献
189.
The purpose of the current study was to examine the degree to which instruction based on stimulus equivalence procedures could be used to teach single-subject design methodology to graduate-level professionals through a Web-based course management system known as Blackboard (see http://www.blackboard.com). Specifically, we used the stimulus equivalence paradigm to teach relations among the names, definitions, graphical representations of the designs, and two practical scenarios of when it would be appropriate to implement each design. Most participants demonstrated the emergence of untaught relations, and some participants showed generalization to novel vignettes and graphs. Relations largely were not maintained at follow-up but were retaught. 相似文献
190.
Saylor S Sidener TM Reeve SA Fetherston A Progar PR 《Journal of applied behavior analysis》2012,45(1):185-190
We evaluated the effects of 3 types of noncontingent auditory stimulation (music, white noise, recordings of vocal stereotypy) on 2 children with autism who engaged in high rates of vocal stereotypy. For both participants, the music condition was the most effective in decreasing vocal stereotypy to near-zero levels, resulted in the highest parent social validity ratings, and was selected as most preferred in treatment preference evaluations. 相似文献