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91.
OBJECTIVE: We ask whether subjective socioeconomic status (SES) predicts who develops a common cold when exposed to a cold virus. DESIGN: 193 healthy men and women ages 21-55 years were assessed for subjective (perceived rank) and objective SES, cognitive, affective and social dispositions, and health practices. Subsequently, they were exposed by nasal drops to a rhinovirus or influenza virus and monitored in quarantine for objective signs of illness and self-reported symptoms. MAIN OUTCOME MEASURES: Infection, signs and symptoms of the common cold, and clinical illness (infection and significant objective signs of illness). RESULTS: Increased subjective SES was associated with decreased risk for developing a cold for both viruses. This association was independent of objective SES and of cognitive, affective and social disposition that might provide alternative spurious (third factor) explanations for the association. Poorer sleep among those with lesser subjective SES may partly mediate the association between subjective SES and colds. CONCLUSIONS: Increased Subjective SES is associated with less susceptibility to upper respiratory infection, and this association is independent of objective SES, suggesting the importance of perceived relative rank to health.  相似文献   
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Simonton (2007 Simonton , D. K. ( 2007 ). The creative process in Picasso's Guernica sketches: Monotonic improvements versus nonmonotonic variants . Creativity Research Journal , 19 , 329344 .[Taylor & Francis Online], [Web of Science ®] [Google Scholar]) offered evidence for his Darwinian theory of creativity—blind nonmonotonic variation and selection—based on ratings of Picasso's preliminary sketches of the components for Guernica. This comment reexamines the sketches, adding two major sources of information: (a) consideration of the changing conceptions of the composition, as well as the components, and (b) inclusion of sketches from Picasso's first vision for his mural, the Studio sketches. Such analysis supports the notion of nonmonotonic variation including backtracking. It also suggests that the final mural, although radically different in its components from the Studio sketches, drew on the composition and theme of that initial vision for the mural, but in a completely reimagined form when a chance event pulled Picasso's thinking in a new direction. This comment also describes how Picasso drew on his expertise throughout his explorations, that lack of knowledge of outcome does not diminish the role of expertise in the artist at work. The terms Darwinian and blind mask this and other features of the creative process, and an alternate vocabulary is suggested.  相似文献   
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Abstract

The concepts and methods used by regulatory agencies worldwide to assess the safety of flavouring additives were designed by and for the flavouring industry. They embody and embed, in routine regulatory practice, the industry's commercial interests in minimising regulatory costs and the risk that the market for its products might be restricted. First sketched out by US flavouring company scientists in the early 1960s, this approach required almost no experimental data, and was highly permissive, relative to both our knowledge (and lack of it) about chemical toxicity and the ways other kinds of food additives are regulated. A ‘realist constructivist’ analysis illustrates how the industry's approach was also anti-scientific and unscientific because it served to discourage scientific investigation of important aspects of the phenomena it purported to evaluate, and because it relied on assumptions and hypotheses that lacked any evidential basis. The industry approach was first used to assess flavourings in the USA, where the industry was allowed to design and run its own regulatory regime. In all other regulatory jurisdictions, the industry's approach was rejected; expert advisors argued that it was incompatible with mandates to protect consumer health. Yet, the approach eventually prevailed everywhere. It did so in large part because of the collective refusal of the flavouring industry over three decades to provide the experimental data that had been requested by the regulatory authorities. This has been a form of regulatory capture, which was triggered by a remarkably effective tactic of non-cooperation with demands for data.  相似文献   
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The earliest characterisation of Australian sex offenders subjected to post‐sentence legislation is presented. Demographic, developmental, clinical, and criminal characteristics were obtained for sex offenders under post‐sentence orders in Western Australia, New South Wales, and Victoria. Data on 50 offenders were recorded from psychological and psychiatric risk assessment reports statutorily required at the initiation of post‐sentence legal proceedings. The findings describe a group of demonstrably dangerous men who exhibited an early onset of sexual offending, high rates of mental disorder, sexual deviance, and antisociality. Their developmental histories are characterised by early deprivation, disadvantage, abuse, early exposure to substance abuse, and social and psychological dislocation. These offenders present a conundrum to criminal justice agencies. They are an objectively unfortunate group and have engaged in significantly harmful behaviours. However, the early onset of their offending suggests that early intervention services, such as those offered by mental health professionals, have a critically important role to play in any effort to alter offending trajectories such as those exhibited in this sample. A paradigm shift in public policy from a post hoc model to a well‐resourced preventative and public health approach to the problem of sexual violence is proposed. Broad treatment implications are also considered.  相似文献   
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