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301.
Face identification and voice identification were examined using a standard old/new recognition task in order to see whether seeing and hearing the target interfered with subsequent recognition. Participants studied either visual or audiovisual stimuli prior to a face recognition test, and studied either audio or audiovisual stimuli prior to a voice recognition test. Analysis of recognition performance revealed a greater ability to recognise faces than voices. More importantly, faces accompanying voices at study interfered with subsequent voice identification but voices accompanying faces at study did not interfere with subsequent face identification. These results are similar to those obtained in previous research using a lineup methodology, and are discussed with respect to the interference that can result when earwitnesses are also eyewitnesses. Copyright © 2010 John Wiley & Sons, Ltd.  相似文献   
302.
Body Integrity Identity Disorder (BIID) is a condition in which individuals experience an intense desire for amputation of an healthy limb. Recently, McGeoch and colleagues provided the first direct evidence that this syndrome may be neurological rather than psychological in its origin. However, before including BIID in body ownership disorders, several concerns should be clarified, exploring other components of body representation and not only somatosensory perception.  相似文献   
303.
Perceivers generally show a poor ability to detect changes, a condition referred to as “Change Blindness” (CB). They are, in addition, “blind to their own blindness”. A common explanation of this “Change Blindness Blindness” (CBB) is that it derives from an inadequate, “photographical” folk-theory about perception. This explanation, however, does not account for intra-individual variations of CBB across trials. Our study aims to explore an alternative theory, according to which participants base their self-evaluations on two activity-dependent cues, namely search time and perceived success in prior trials. These cues were found to influence self-evaluation in two orthogonal ways: success-feedback influenced self-evaluation in a global, contextual way, presumably by recalibrating the norm of adequacy for the task. Search time influenced it in a local way, predicting the success of a given trial from its duration.  相似文献   
304.
Lynch syndrome is the most common hereditary colorectal cancer syndrome and the most common cause of hereditary endometrial cancer. Identifying and evaluating families for Lynch syndrome is increasing in complexity due to the recognition that: family history-based clinical criteria lack sensitivity and specificity; genetic testing for Lynch syndrome continues to evolve as understanding of the molecular mechanisms underlying it evolves; and the Lynch syndrome phenotype encompasses multiple organ systems and demonstrates overlap with other hereditary cancer syndromes. This document is a summary of considerations when evaluating individuals and families for Lynch syndrome, including information on cancer risks, diagnostic criteria, tumor and genetic testing strategies, and the management of individuals with this condition.  相似文献   
305.
The standard of care treatment for chronic hepatitis C viral infection (HCV) is a combination of pegylated interferon alfa and ribavirin for 24-48?weeks according to the virus genotype. This therapy is known to have multiple neuropsychiatric side effects. A major concern when evaluating a patient for HCV treatment with a known history of a psychiatric disorder is the risk that the patient's psychiatric disorder will flare or become unmanageable. The possibility of precipitating depression, confusion, mania, psychosis, hallucinations, or suicidal ideation or attempt is frequently an obstacle to treatment. We present the case of a 50?year-old man with HCV and an extensive psychiatric history involving alcoholism, depression, and suicidality who participated in a psychoeducation group to help prepare him for treatment with pegylated interferon alfa/ribavirin therapy. Though the patient derived much benefit from the psychoeducation group, by the time of evaluation for HCV treatment two months after the group ended he had relapsed back into a depressive episode with suicidal thoughts. His acute psychiatric status made him unacceptable for pegylated interferon alfa/ribavirin therapy. Psychoeducation groups show promise for helping patients with chronic medical illness to be ready for and endure intensive medical treatment that has substantial psychiatric side effects. The challenge is to help patients overcome barriers to treatment, particularly psychosocial problems, because available treatments are increasingly effective.  相似文献   
306.
Both humans and non-human animals have the ability to navigate and make decisions within complex environments. This ability is largely dependent upon learning and memory processes, many of which are known to depend on NMDA-sensitive receptors. When humans come to difficult decisions they often pause to deliberate over their choices. Similarly, rats pause at difficult choice points. This behavior, known as vicarious trial and error (VTE), is hippocampally dependent and entails neurophysiological representations of expectations of future outcomes in hippocampus and downstream structures. In order to determine the dependence of VTE behaviors on NMDA-sensitive receptors, we tested rats on a Multiple-T choice task with a reward-delivery reversal known to elicit VTE. Rats under the influence of NMDA-receptor antagonists (CPP) showed a significant reduction in VTE, particularly at the reward reversal, implying a role for NMDA-sensitive receptors in the generation of vicarious trial and error behaviors.  相似文献   
307.
Contingent negative variation (CNV) topography, hemispheric asymmetry and time-course were investigated in healthy subjects and non-medicated paranoid schizophrenic patients in two antisaccade paradigms with the short (800-1000 ms) and long (1200-1400 ms) durations of the fixation period. EEG and electrooculogram (EOG) were recorded. Saccade characteristics and mean amplitudes of slow cortical potentials time-locked to peripheral target were analyzed in 23 healthy volunteers and 19 schizophrenic patients. Compared to healthy control subjects, schizophrenic patients had significantly slower antisaccades and committed significantly more erroneous saccades in the both antisaccade tasks. The prolongation of the fixation period resulted in noticeable decrease of error percent in patients group. The analysis of CNV time-course has revealed two distinct stages in both groups. The early CNV stage was represented by a negative wave with the maximal amplitude over midline fronto-central area, and the late stage was characterized by increased CNV amplitude at the midline and left parietal electrode sites. In healthy subjects the simultaneous activation of frontal and parietal areas was observed in the paradigm with the shorter fixation interval; the increase of the fixation period produced consecutive activation of these areas. Schizophrenic patients' CNV amplitude was generally smaller than that of healthy subjects. The most pronounced between-group differences of the negative shift amplitude were revealed at frontal electrode sites during the early CNV stage in both modifications of the antisaccade task. The deficit of frontal activation revealed in patients at the early stage of antisaccade preparatory set in both antisaccadic paradigms may be related to pathogenesis of paranoid schizophrenia.  相似文献   
308.
The capacity to reason about the false beliefs of others is classically considered the benchmark for a fully fledged understanding of the mental lives of others. Although much is known about the developmental origins of our understanding of others' beliefs, we still know much less about the evolutionary origins of this capacity. Here, we examine whether non-human primates - specifically, rhesus macaques (Macaca mulatta) - share this developmental achievement. We presented macaques with a looking-time measure of false belief understanding, one that had recently been developed for use with 15-month-old human infants. Like human infants, monkeys look longer when a human experimenter fails to search in the correct location when she has accurate knowledge. In contrast to infants, however, monkeys appear to make no prediction about how a human experimenter will act when she has a false belief. Across three studies, macaques' pattern of results is consistent with the view that monkeys can represent the knowledge and ignorance of others, but not their beliefs. The capacity to represent beliefs may therefore be a unique hallmark of human cognition.  相似文献   
309.
In human causal learning, positive patterning (PP) and negative patterning (NP) discriminations are often acquired at roughly the same rate, whereas PP is learned faster than NP in most experiments with nonhuman animals. One likely reason for this discrepancy is that most causal learning scenarios encourage participants to treat the presentation and omission of the relevant outcome as two events of comparable significance and likelihood. To investigate this, the current experiments compared PP and NP using a predictive learning paradigm based on a mock gambling task. In Experiment 1, one outcome (winning) was made more salient by being less frequent than the alternative outcome (losing). Under these circumstances, PP was learned faster than NP. In Experiment 2, subjects learned two PP and two NP discriminations, one involved win versus no change outcomes, the other involved lose versus no change outcomes. The subjects learned PP faster than NP, but only when discriminating win from no change. We argue that a difference in difficulty between PP and NP relies on a difference in the salience of the outcomes, consistent with the predictions of a relatively simple model of associative learning.  相似文献   
310.
This study examined demographic and anthropometric variables as predictors of ideal body mass index (BMI) from cross-sectional, archival, self-reported data from the Psychology of Size Survey of 4014 U.S. residents collected in 2007. As hypothesized, ideal BMI can be predicted by a within gender hierarchical multiple regression analysis with the predictor variables of age, number of clothing sizes from ideal size, and current BMI; these variables account for 54.1% of variance in women's ideal BMI and 65.5% of variance in men's ideal BMI. Findings also demonstrated a logarithmic relationship between current BMI and ideal BMI, with increasing variance in ideal BMI for individuals with high current BMIs. These findings evidence the strong role of current body characteristics in the formation of ideals. Understanding how individuals conceptualize body ideals can inform researchers and practitioners alike, as this evidence has important implications related to both medical and psychological health.  相似文献   
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