Injection of 5,7-dihydroxytryptamine into the B3 raphe region of neonatal rat pups induces hyperalgesia but only slight alterations in ingestion-related behaviors.

The effects of intrabrainstem injections of the neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) into the B3 raphe region (nucleus raphe magnus and nucleus reticularis paragigantocellularis) on early ingestive behavior and nociception were assessed in Sprague-Dawley rat pups during the first postnatal week. Lesions resulted in a marked depletion of serotonin (5HT) in hindbrain without influencing 5HT levels in forebrain. Pretreatment with desipramine (DMI) resulted in a sparing of noradrenergic neurons from neurotoxic effects. The B3 lesion resulted in significant hyperalgesia as reflected by decreased latencies in tail flick testing. Although nipple attachment latencies in suckling tests were slightly increased by the lesion, no notable effects on mouthing or other ingestive-related behaviors were observed in testing conducted in an independent ingestion paradigm. These results suggest that whereas B3 serotonergic neurons may be functioning in an adult-typical manner to regulate analgesia during the early postnatal period, this raphe region may play only a slight role in the modulation of ingestion-related behaviors early in life.     

Learning artificial grammars: No evidence for the acquisition of rules

Two experiments investigated whether there is evidence for acquisition of rules in implicit artificial grammar learning (AGL). Two different methods were used in meeting this goal, multiple regression analysis and analysis of receiver-operating characteristics (ROCs). By means of multiple regression analysis, several types of knowledge were identified that were used in judgments of grammaticality, for example, about single letters and about larger stimulus fragments. There was no evidence for the contribution of rule knowledge. The ROCs were in accord with a similarity-based account of AGL and thus did not support the notion that rule knowledge is acquired in AGL either. Simulations with a connectionist model corroborated the conclusion that the results were in accord with a similarity-based, associative account.     

Kognitive Lernermodellierung

Different types of learner models and their usefulness for tutoring have been discussed widely since the beginning of intelligent tutoring systems. In this paper we compare pragmatic and cognitive approaches of learner modeling. Pragmatic approaches consider relevant learner features for adaptive methods in learning environments and adapt different aspects of instruction to a restricted model representing these features. Cognitive approaches aim for a psychologically adequate modeling of human problem solving. We introduce the case-based learner model ELM as an example of a cognitive approach to learner modeling. The learning environments ELM-PE and ELM-ART use ELM for adaptional methods on conceptual, plan, and episodic levels and provide individual help and learning support. Especially in the case of integrated learning environments like ELM-ART which support a variety of learning activities, a combination of pragmatic and cognitive learner models is proposed to be a necessary and useful solution.     

Human taste contrast and self-reported measures of anxiety.

Successive negative taste contrast in humans was demonstrated with a common taste stimulus, i.e., cherry-flavored Kool-Aid. A total of 31 male and female college-aged participants rated a 7% sucrose solution which was cherry-flavored as less sweet when it was preceded by a 28% rather than a 7% sucrose solution which was cherry-flavored. Because drugs such as the benzodiazepines affect taste contrast in rats and act as anxiolytics in humans, the present experiment also examined whether several self-reported measures of anxiety were related to taste contrast in humans. Neither scores on Taylor's Manifest Anxiety Survey nor those on the State-Trait Anxiety Inventory were related to "sweetness" ratings or contrast effects.     

Self-Report Measures of Parental Self-Efficacy: A Systematic Review of the Current Literature

Parenting self-efficacy (PSE) describes a parent’s belief in their ability to perform the parenting role successfully. Higher levels of PSE have consistently been shown to be correlated with a wide range of parenting and child outcomes. Consequently, many parenting interventions aim to improve PSE. PSE measurement has typically been via self-report measures. However, the wide range of available measures has resulted in their limited use, inconsistent terminology and ambiguous theoretical grounding. The purpose of this systematic review was to examine the psychometric and administrative qualities of the available PSE measures and offer clarity to the terminology and the theory underpinning their use so that the future use of PSE measures can be appropriate. Eleven electronic databases were searched. Articles were included if they introduced a new measure or were psychometric evaluations of an available measure of PSE for parents of children (from infancy until 18 years of age). Thirty-four measures were identified and their psychometric and administrative qualities were examined. Overall, the quality of the available measures was varied. Whilst this review makes recommendations regarding PSE measures for parents of infants through to adolescents, some caution should be applied when choosing the most appropriate measure. The theoretical grounding of each measure was clarified so that appropriate measures can be chosen under the relevant circumstances. The implications of refinement of the available measures are discussed and further research into improving PSE measurement is identified.     

Connectionist models of artificial grammar learning: what type of knowledge is acquired?

Two experiments are presented that test the predictions of two associative learning models of Artificial Grammar Learning. The two models are the simple recurrent network (SRN) and the competitive chunking (CC) model. The two experiments investigate acquisition of different types of knowledge in this task: knowledge of frequency and novelty of stimulus fragments (Experiment 1) and knowledge of letter positions, of small fragments, and of large fragments up to entire strings (Experiment 2). The results show that participants acquired all types of knowledge. Simulation studies demonstrate that the CC model explains the acquisition of all types of fragment knowledge but fails to account for the acquisition of positional knowledge. The SRN model, by contrast, accounts for the entire pattern of results found in the two experiments.

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Interstitial deletion on chromosome 5q33.3q35.1 in a 6-year-old girl -- neuropsychological findings and follow-up in an extremely rare chromosomal aberration.

Interstitial deletion on chromosome 5q33.3q35.1 is an extremely rare chromosomal aberration for which a characteristic syndrome could not yet be delineated. In most patients with 5q deletions severe mental retardation is described. Recently, Spranger et al. (2000) described the case of a 4-year-old girl with a de novo deletion on 5q33.3q35.1 presenting only with mild psychomotor delay, minor facial anomalies, and seizures. The patient was admitted for outpatient neuropsychological assessment when she was 6.2 years old. Neurocognitive tests revealed an overall developmental delay of about 32 months and an intelligence score in the range of mild mental retardation. Her cognitive phenotype was characterized by a considerable visual-spatial deficit in the form of disorganized drawings or block designs indicating a profound lack of cohesion and overall global organization (decay of gestalt). The patient's behavioral phenotype was dominated by a distinct disinhibition syndrome demonstrating severe hyperactivity, utilization behavior, and aggressive behavior.     

The relationship between political participation and civic community of migrants in the Netherlands

This article examines the relationship between different forms of political participation and the civic participation in organizations of ethnic minorities in the Netherlands. We have investigated the turnout rates and voting behaviour of migrants, the participation of councillors from ethnic minority groups and party of officials in four cities and the organizations of ethnic minorities in Amsterdam and on a national level. The combination of all this information supplies us with a picture of the civic community of the ethnic groups in the Netherlands and we theorize about explanations on differences between these groups.