Can learning potential in schizophrenia be assessed with the standard CVLT‐II? An exploratory study

This study examined the potential of using the regular administration of a common neuropsychological test, the CVLT-II, to assess learning potential in schizophrenia. Based on List A trial 1 performance and the learning slope, a schizophrenia sample was divided into three learning potential groups (non-learners, learners and high-achievers) that differed in the use of learning strategies. High-achievers utilized more semantic clustering than learners and non-learners, and non-learners were less consistent in words recalled than the other two groups. This standard administration approach is a promising, time-saving alternative to the modified tests of learning potential used so far.     

Inadequate and infrequent are not alike: ERPs to deviant prosodic patterns in spoken sentence comprehension

The current study on German investigates Event-Related brain Potentials (ERPs) for the perception of sentences with intonations which are infrequent (i.e. vocatives) or inadequate in daily conversation. These ERPs are compared to the processing correlates for sentences in which the syntax-to-prosody relations are congruent and used frequently during communication. Results show that perceiving an adequate but infrequent prosodic structure does not result in the same brain responses as encountering an inadequate prosodic pattern. While an early negative-going ERP followed by an N400 were observed for both the infrequent and the inadequate syntax-to-prosody association, only the inadequate intonation also elicits a P600.     

Perceived trustworthiness of online shops

• Trust has been found to be crucial for consumer behaviour towards online shops. However, existing studies on the role of trust in electronic commerce are mainly based on ad hoc scales to measure trustworthiness, merely rely on self‐reported consequences of trust such as intention to buy, and focus on low‐risk products.
• In a web‐based study, 634 participants interacted with a provider of medical goods, that is a simulated online pharmacy. The study develops and employs a psychometrically sound scale for assessing perceived trustworthiness of online shops. Moreover, it examines the impact of trustworthiness on both consumers' intended and actual behaviour towards online shops.
• Results show that trustworthiness promotes both intention to buy and actual financial risk taking. Perceived risk was not found to moderate the relationship between trustworthiness and intention to buy. Instead, trustworthiness partially mediated the influence of perceived risk on intention to buy. The results from the scale development challenge multidimensional conceptualizations of trust; comparing this finding with other studies suggests that the duration of the relationship might moderate the dimensionality of trust.

Copyright © 2008 John Wiley & Sons, Ltd.     

Dopamine D1 and D2 receptors in the nucleus accumbens core and shell mediate Pavlovian-instrumental transfer

Pavlovian stimuli previously paired with food can markedly elevate the rate of food-reinforced instrumental responding. This effect, termed Pavlovian-instrumental transfer (PIT), depends both on general activating and specific cueing properties of Pavlovian stimuli. Recent evidence suggests that the general activating properties of Pavlovian stimuli are mediated by mesoaccumbens dopamine systems; however, the role of NAC dopamine D1 and D2 receptors is still unknown. Here we examined the effects of a selective dopamine D1 and D2 receptor blockade in the shell and core subregion of the NAC on general PIT. Rats were trained to press a single lever for food, and the effect of a single Pavlovian stimulus previously associated with the same food on performance of that lever was measured in extinction. Results reveal that PIT, that is, the increase in instrumental responding during presentation of the Pavlovian stimulus, was reduced by microinjections of the dopamine D1 receptor antagonist SCH-23390 and, less pronounced, by microinjections of the dopamine D2 receptor antagonist raclopride into the NAC core or shell, respectively. Our data suggest that dopamine D1 and D2 receptors in the NAC core and shell mediate the general activating effects of Pavlovian stimuli on instrumental behavior.     

Using instant messaging for Internet-based interviews.

One method of data collection that has rarely been applied online is the one-on-one interview. Because of its widespread use, the Internet-based service instant messaging (IM) seems to be suitable to conduct scientific online interviews. A unique benefit of IM is the existence of public address books. These can be used both as a sampling frame and as a cross-reference to validate respondents' demographic data. The feasibility of IM interviews was examined in a WWW survey as well as in actual IM interviews that were combined with an experimental manipulation of the request for participation. On the basis of self-reports, respondent behavior, and data in the address books, the studies have demonstrated that the risk of receiving false data in IM interviews is small. Not only is the quality of the obtainable data satisfying but the contact rate, response rate, and retention rate as well. Moreover, the experimental test demonstrated that the response rate is influenced by the information provided in the chat request. On the basis of the study results, recommendations are given as to when and how IM interviews should be used as a data collection method.     

Nightmare frequency and femininity/masculinity

Several large-scale studies showed that women tend to report nightmares more often than men. Despite this robust finding, empirically tested interpretations of these sex differences are lacking. Levin and Nielsen put forward the hypothesis that sex-specific socialization might be one of the risk factors for nightmare occurrence. The present findings of an online survey indicate that expressivity/femininity and instrumentality/masculinity were related to nightmare fre quency and, thus, supported this hypothesis. Since the sex difference in nightmare frequency was not fully explained by these two variables, future studies should investigate other variables--in addition to sex-role orientation--like depressive symptoms, history of sexual and/or physical abuse, ruminative coping styles, and physiological measures of processing emotional stimuli within the brain.     

Trait BIS predicts alpha asymmetry and P300 in a Go/No‐Go task

Inspired by the revised Behavioural Inhibition System (BIS) theory the present study probed the association between individual differences in Trait BIS and electroencephalogram indicators of conflict processing/inhibition. Sixty‐nine male participants either high or low in Trait BIS completed a Go/No‐Go task while the electroencephalogram was recorded. As expected, Trait BIS was associated with the No‐Go‐anteriorisation of the P300 event‐related potential (i.e. an index of response inhibition presumably generated in the dorsal anterior cingulate—an area implicated in conflict processing) and with No‐ Go‐related changes towards left frontal alpha activity (i.e. presumably more activity in right prefrontal cortex—an area implicated in response inhibition). These findings support the role of conflict processing attributed to BIS functioning in the revised theory. Copyright © 2009 John Wiley & Sons, Ltd.     

A model for production, perception, and acquisition of actions in face-to-face communication

The concept of action as basic motor control unit for goal-directed movement behavior has been used primarily for private or non-communicative actions like walking, reaching, or grasping. In this paper, literature is reviewed indicating that this concept can also be used in all domains of face-to-face communication like speech, co-verbal facial expression, and co-verbal gesturing. Three domain-specific types of actions, i.e. speech actions, facial actions, and hand-arm actions, are defined in this paper and a model is proposed that elucidates the underlying biological mechanisms of action production, action perception, and action acquisition in all domains of face-to-face communication. This model can be used as theoretical framework for empirical analysis or simulation with embodied conversational agents, and thus for advanced human–computer interaction technologies.     

The significance of overvaluation of shape and weight in binge eating disorder

As publication of DSM-V draws near, research is needed to validate the diagnostic scheme for binge eating disorder (BED). Shape and weight overvaluation has stimulated considerable debate in this regard, given associations with psychosocial impairment and poor treatment outcome in BED. This study sought to further explore the convergent validity and diagnostic specificity of shape and weight overvaluation in BED. A total of 160 women with BED, and 108 women with non-eating disordered psychiatric disorders were recruited from the community. Women with BED were classified as more or less severe based on a global measure of eating-related psychopathology; subsequent receiver operating characteristics analysis determined that a threshold of at least “moderate” overvaluation best predicted membership into a more severe group. BED participants with threshold overvaluation exhibited poorer psychosocial functioning than those with subthreshold overvaluation, as well as participants with other psychiatric disorders. Discriminant function analysis revealed that threshold overvaluation predicted a diagnosis of BED versus other psychiatric disorder with 67.7% accuracy. Results suggest that shape and weight overvaluation is a useful diagnostic specifier in BED. Continued research is warranted to examine its predictive validity in natural course and treatment outcome studies.     

Monitor yourself! Deficient error-related brain activity predicts real-life self-control failures

Despite their immense relevance, the neurocognitive mechanisms underlying real-life self-control failures (SCFs) are insufficiently understood. Whereas previous studies have shown that SCFs were associated with decreased activity in the right inferior frontal gyrus (rIFG; a region involved in cognitive control), here we consider the possibility that the reduced implementation of cognitive control in individuals with low self-control may be due to impaired performance monitoring. Following a brain-as-predictor approach, we combined experience sampling of daily SCFs with functional magnetic resonance imaging (fMRI) in a Stroop task. In our sample of 118 participants, proneness to SCF was reliably predicted by low error-related activation of a performance-monitoring network (comprising anterior mid-cingulate cortex, presupplementary motor area, and anterior insula), low posterror rIFG activation, and reduced posterror slowing. Remarkably, these neural and behavioral measures predicted variability in SCFs beyond what was predicted by self-reported trait self-control. These results suggest that real-life SCFs may result from deficient performance monitoring, leading to reduced recruitment of cognitive control after responses that conflict with superordinate goals.