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241.
This research investigated a new method to measure momentary affective clarity indirectly, which is based on latencies of responses to state affect items. Three studies revealed that this indirect measure of momentary clarity demonstrated high reliability and stability as well as convergent and predictive validity. The indirect measure was associated with dispositional clarity when the concept of clarity was activated before measuring response latencies (Studies 1 and 2) and was related to self-reports of momentary clarity (Study 3). Furthermore, Study 3 demonstrated that indirectly measured clarity decreased after an affectively complex film. Indirectly, but not directly, measured momentary clarity predicted a more positive affective state at the end of the study. This effect was mediated by affect regulation.  相似文献   
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243.
Patients with advanced cancer often suffer from existential distress. Although a variety of effective psychotherapeutic interventions for the treatment of psychological distress in cancer patients are available, concerns such as hope and meaning of life are only occasionally at the center of therapeutic attention. During recent years growing efforts have been made to develop and evaluate meaning-based interventions for cancer patients, particularly in the Anglo-American research literature. Meaning-based interventions are often realized as group therapy approaches to reduce emotional and spiritual distress and to promote hope, courage and control, to mobilize internal resources and to discuss future goals despite a noticeable limited life expectancy. Further aims include strengthening a patient??s self-esteem and sense of dignity, to appreciate strengths and past achievements, to reduce feelings of isolation, to strengthen the relationship with the partner and family members and to improve communication with the professional healthcare team.  相似文献   
244.
In two experiments, each including a simple reaction time (RT) task, a localization task, and a passive oddball paradigm, the physical similarity between two dichotically presented auditory stimuli was manipulated. In both experiments, a redundant signals effect (RSE), high localization performance, and a reliable mismatch negativity (MMN) was observed for largely differing stimuli, suggesting that these are coded separately in auditory memory. In contrast, no RSE and a localization rate close to chance level (experiment 1) or at chance (experiment 2) were observed for stimuli differing to a lesser degree. Crucially, for such stimuli a small (experiment 1) or no (experiment 2) MMN were observed. These MMN results indicate that such stimuli tend to fuse into a single percept and that this fusion occurs rather early within information processing.  相似文献   
245.
Patients with inflammatory bowel diseases (IBDs) have a higher risk of developing colorectal cancer (CRC) than the general population. Furthermore, chronic psychosocial stress increases the likelihood of developing IBD and multiple types of malignant neoplasms, including CRC. Here, for the first time, we investigate the effects of chronic psychosocial stress in male mice on an artificially induced CRC, by employing the chronic subordinate colony (CSC) housing paradigm in combination with the reliable azoxymethane (AOM)/dextran sodium sulfate (DSS) CRC model. Colonoscopy revealed that CSC mice showed accelerated macroscopic suspect lesions. In addition, more CSC mice developed low-grade dysplasia (LGD) and/or high-grade dysplasia (HGD) in the colonic tissue compared to the single-housed control mice (SHC). CSC mice showed an increased number of Ki67+ and a decreased number of terminal deoxynucleotidyl transferase dUTP nick end labeling epithelial cells in colonic tissue. Colonic liver receptor homolog-1 (LRH-1), cyclooxygenase II (COXII), tumor necrosis factor, forkhead box P3 (FoxP3) mRNA as well as colonic ?-catenin, COXII, and LRH-1 protein expression were also increased in CSC compared with SHC mice. Although the number of CD4+ Th cells was increased, a tendency toward a decreased colonic interferon-γ (IFN-γ) mRNA expression was observed. Furthermore, despite an increased percentage of CD3+ cells and CD3+/FoxP3+ double-positive cells within mesenteric lymph node cells of CSC mice, IFN-γ secretion from these cells was unaffected. Altogether, our results suggest that chronic psychosocial stress increases the risk for AOM/DSS-induced and, thus, inflammation-related CRC. Finally, assessment of additional time points may test whether the shift from tumor-protective Th1 cell to regulatory T-cell immunity represents a consequence of increased carcinogenesis or a causal factor involved in its development.  相似文献   
246.
There is a long-standing debate in the area of speech production on the question of whether only words selected for articulation are phonologically activated (as maintained by serial-discrete models) or whether this is also true for their semantic competitors (as maintained by forward-cascading and interactive models). Past research has addressed this issue by testing whether retrieval of a target word (e.g., cat) affects--or is affected by--the processing of a word that is phonologically related to a semantic category coordinate of the target (e.g., doll, related to dog) and has consistently failed to obtain such mediated effects in adult speakers. The authors present a series of experiments demonstrating that mediated effects are present in children (around age 7) and diminish with increasing age. This observation provides further evidence for cascaded models of lexical retrieval.  相似文献   
247.
In this article, the authors report 2 experiments that investigated the sources of information used in transfer and nontransfer tasks in artificial grammar learning. Multiple regression analyses indicated that 2 types of information about repeating elements were crucial for performance in both tasks: information about the repetition of adjacent elements and information about repetition of elements in the whole item. Similarity of test items to specific training items and chunk information influenced participants' judgments only in nontransfer tasks.  相似文献   
248.
Humor styles have been found to be associated with well-being, however, no study has addressed the distinct well-being associations of combinations of humor styles, that is, humor types, yet. The present study thus aimed at investigating which combinations of humor styles exist and to which extent these humor types are associated with well-being. In an online questionnaire, the Humor Styles Questionnaire (HSQ, Martin et al. J Res Pers 37:48–75, 2003), self-regulatory strategies, self-esteem, and well-being instruments were administered to a German sample. Exploratory and confirmatory factor analyses replicated the underlying structure of the HSQ. With hierarchical clustering, we found evidence for three humor types (endorsers, humor deniers, and self-enhancers), which differed in group means for self-esteem, self-regulatory strategies, and well-being. Findings provide further evidence for the positive well-being correlates of self-enhancing humor, and distinctly address the positive correlates of aggressive and self-defeating humor being absent. It is discussed that humor styles cannot be conceptualized as beneficial or detrimental per se, but have to be regarded in context.  相似文献   
249.
In a go/no-go experiment, semantic redundancy gain was assessed for responses to single written words. Specifically, we asked participants to respond only to words whose meaning matched at least one semantic target feature—that is, the target category (e.g., animal), the target color (e.g., gray), or both. On redundant-target trials, the word (e.g., elephant) matched both semantic target features (i.e., gray and animal). On single-target trials, the word (e.g., beaver) matched one target feature (i.e., animal) and a nontarget feature (i.e., brown). We observed shorter reaction times in the redundant-target condition than in the faster single-target condition. Hence, the present study provides the first evidence that redundancy gain is not limited to responses to redundant proximal stimulus features but can also be observed for responses to semantic feature information.  相似文献   
250.
As publication of DSM-V draws near, research is needed to validate the diagnostic scheme for binge eating disorder (BED). Shape and weight overvaluation has stimulated considerable debate in this regard, given associations with psychosocial impairment and poor treatment outcome in BED. This study sought to further explore the convergent validity and diagnostic specificity of shape and weight overvaluation in BED. A total of 160 women with BED, and 108 women with non-eating disordered psychiatric disorders were recruited from the community. Women with BED were classified as more or less severe based on a global measure of eating-related psychopathology; subsequent receiver operating characteristics analysis determined that a threshold of at least “moderate” overvaluation best predicted membership into a more severe group. BED participants with threshold overvaluation exhibited poorer psychosocial functioning than those with subthreshold overvaluation, as well as participants with other psychiatric disorders. Discriminant function analysis revealed that threshold overvaluation predicted a diagnosis of BED versus other psychiatric disorder with 67.7% accuracy. Results suggest that shape and weight overvaluation is a useful diagnostic specifier in BED. Continued research is warranted to examine its predictive validity in natural course and treatment outcome studies.  相似文献   
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