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611.
Tércio Apolinário-Souza Ana Flávia Santos Almeida Natália Lelis-Torres Juliana Otoni Parma Grace Schenatto Pereira Guilherme Menezes Lage 《Journal of motor behavior》2020,52(5):515-526
AbstractVariable practice promotes a higher level of motor learning than constant practice. The glutamate receptors, n-methyl-d-aspartate (NMDA) and alfa-amino-3-hydroxy-5-methyl-4-isoxazolepropionic (AMPA), have been associated with the changes in motor cortex that occur throughout the process of motor learning. Considering that, it is possible that variable practice is more associated with the NMDA and AMPA receptors than constant practice. This study aimed ao investigating the association between the glutamate receptors, NMDA and AMPA, and constant and variable practice schedules. Seventy-eight male mice practiced the rotarod task in a constant or variable scheduling, in two consecutive days (acquisition phase). Learning tests were performed 24?h and 10?days after the end of the acquisition phase. Variable practice was more associated with the NMDA receptor and had a greater AMPA receptor expression than constant practice. The results suggest that the benefits of variable practice are result of both the greater dependency on the NMDA receptor and the greater AMPA receptor expression. 相似文献
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Sarah D Pressman Sheldon Cohen Gregory E Miller Anita Barkin Bruce S Rabin John J Treanor 《Health psychology》2005,24(3):297-306
Antibody response to the influenza immunization was investigated in 83 1st-semester healthy university freshmen. Elevated levels of loneliness throughout the semester and small social networks were independently associated with poorer antibody response to 1 component of the vaccine. Those with both high levels of loneliness and a small social network had the lowest antibody response. Loneliness was also associated with greater psychological stress and negative affect, less positive affect, poorer sleep efficiency and quality, and elevations in circulating levels of cortisol. However, only the stress data were consistent with mediation of the loneliness-antibody response relation. None of these variables were associated with social network size, and hence none were potential mediators of the relation between network size and immunization response. 相似文献
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ABSTRACT: Suicide rates vary greatly by sex and race but the methods employed by these groups and changes in those methods have been studied neither closely nor systematically across time. In the present study annual official national statistics for specific methods of suicide by sex and racial group from 1923 to 1978 were examined. During this time period shifts were found among groups in the proportions of various suicide methods employed, most notably for women and Asian-Americans. Generally, firearm use increased among nearly all ethnic/racial-sex groups while the use of poisons declined. Although women continue to be more likely than men to kill themselves with solid and liquid poisons, in very recent years firearms have become a more common method. Among Japanese - and Chinese-Americans of both sexes the most frequently employed method has been hanging. Although this is still the case, the proportions have declined over time while the use of firearms has increased. Explanations are offered for the noted changes in method choice with particular attention being given to acculturation and changing societal roles. 相似文献
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