Communication of Information about Genetic Risks: Putting Families at the Center

Genetic information is a family affair. With the expansion of genomic technologies, many new causal genes and variants have been established and the potential for molecular diagnoses increased, with implications not only for patients but also their relatives. The need for genetic counseling and intrafamilial circulation of information on genetic risks grew accordingly. Also, the amount and, particularly, the complexity of the information to convey multiplied. Sharing information about genetic risks with family members, however, has never been an easy matter and often becomes a source of personal and familial conflicts and distress. Ethical requisites generally prevent healthcare professionals from directly contacting their consultands' relatives (affected or still at risk), who often feel unsupported throughout that process. We discuss here the communication of genetic risks to family members. We first consider genomic testing as a basis for family‐centered health care, as opposed to a predominant focus on the individual. We reviewed the literature on sharing genetic risk information with family members, and the associated ethical issues for professionals. Some clinical cases are presented and discussed, and key issues for meeting the needs of individuals and families are addressed. We argue that genetic information is inextricably linked to the family and that communicating about genetic risks is a process grounded within the broader milieu of family relationships and functioning. We conclude for the need for a more family‐centered approach and interventions that can promote sensitive attitudes to the provision of genetic information to and within the family, as well as its inclusion in educational and training programmes for genetic healthcare professionals.     

Object substitution masking and the object updating hypothesis

The object updating hypothesis of object substitution masking proposes that the phenomenon arises when the visual system fails to individuate target and mask at the level of object token representations. This hypothesis is tested in two experiments using modifications of the dot mask paradigm developed by Lleras and Moore (2003). Target—mask individuation is manipulated by the presentation of additional display items that influence the linking apparent motion seen between a target and a spatially separated mask (Experiment 1), and by the use of placeholders that maintain the target object’s presence during mask presentation (Experiment 2). Results in both cases are consistent with the updating hypothesis in showing significantly reduced masking when the conditions promoted target—mask individuation. However, in both experiments, some masking was still present under conditions of individuation, an effect we attribute to attentional capture by the mask.     

The relationship between personality, approach to learning and academic performance

This study considers the relationship between students' approaches to learning, as measured by a short-form of Entwistle and Tait's (1995) Revised Approaches to Studying Inventory (RASI), the Big Five personality factors, as measured by Cattell's 16PFi, and the background variables of age, gender and prior educational achievement and academic performance. Subjects were 146 social science undergraduate students at a university in Scotland. Structural equation modelling identifies the Big Five personality factor scores account for between 22.7% and 43.6% of the variance across scores on the three approach to learning dimensions. Four of the Big Five personality factors and the three approach to learning dimensions were found to be poor predictors of academic performance. A linear regression analysis with academic performance as the dependent variable and age, prior educational attainment and conscientiousness as independent variables, accounted for 24.1% of the variance in performance. Our investigation suggests approach to learning is a subset of personality. However, we conclude it makes sense to measure these two groups of variables separately in educational settings.     

“There's more love between us”: The parental experience of attending Mellow Babies,a targeted,early intervention program for parents and their babies

It is recognized that parenthood in the context of psychosocial adversity can have negative implications for infant development. Parenting programs are the first line of intervention to improve outcomes for families; however, evidence for the effectiveness of group-based, targeted early interventions is still scarce. Preliminary findings indicate Mellow Babies (MB) as a promising group-based parenting program for families at risk for parenting difficulties. Using thematic analysis, we aimed to understand: (i) the aspects of the intervention that enabled parents to complete the program and (ii) the relational and behavioral changes perceived as valuable for parents and their babies post-intervention. In total, 68 parents residing in the United Kingdom were interviewed after completing MB (49 mothers and 19 fathers; 88% self-identified as British). Three themes and six subthemes were generated from the data. Parents identified several intervention components as beneficial, including the facilitators' interpersonal skills and multi-dimensional, group-based approach. Participant reflections highlighted three underlying mechanisms that enabled positive change: (i) the sense of community cultivated within the group, (ii) the process of formulating and re-conceptualizing one's difficulties, and (iii) the opportunity to reshape interpersonal interactions. Findings are discussed within the context of perinatal and infant mental health.     

Properties of the item score matrix

A method of deriving from the item score matrix all the usual statistics describing the performance on a test of a group of examinees is given. Since this matrix usually is not actually written out, but is implicit in a set of punched cards, a method of working from a more compact matrixF is described. A numerical example is presented. Applications and advantages of the method are cited, as compared with that of recording only the examinees' test scores and the item difficulties.     

Transdiagnostic Clinical Staging for Childhood Mental Health: An Adjunctive Tool for Classifying Internalizing and Externalizing Syndromes that Emerge in Children Aged 5–11 Years

Clinical Child and Family Psychology Review - Clinical staging is now recognized as a key tool for facilitating innovation in personalized and preventative mental health care. It places a strong...     

Observation of strain distributions in partially relaxed In0.2Ga0.8As on GaAs using electron channelling contrast imaging

Electron channelling contrast imaging (ECCI) has been used to image misfit dislocations between single epitaxial layers (epilayers) of In0.2Ga0.8As grown on GaAs (001). Bulk specimens of the as-grown material were examined over a range of epilayer thickness from 25 to 3000 nm. Spectral analysis of ECCI intensity traces was used to establish whether strain fields from the individual dislocations overlapped. Significant overlapping of strain fields was first observed at an epilayer thickness of 100 nm which corresponds well to the onset of macroscopic strain relaxation.     

Delayed offset of distracters masks a local target

Object substitution masking (OSM) is observed when a brief target surrounded with a mask is presented among distracter stimuli and cannot be identified when it and the distracters disappear but the mask remains in view. We probed whether OSM also occurs without a local mask object when the distracters remain after target offset. We also varied the congruence between the local target and the global search display and the grouping properties of the delayed offset distracters. A target was briefly presented in a global object configuration of distracters that had delayed offset. Results showed that OSM could be observed with delayed offset of distracters grouped into a global mask shape. Congruence of the shapes of the global and local objects did not affect OSM, suggesting that a generalized abstract visual pattern representation of the global object may not be involved in OSM nor did the grouping properties of the delayed offset distracters influence OSM.