The social risk hypothesis of depressed mood: evolutionary, psychosocial, and neurobiological perspectives

The authors hypothesize that depressed states evolved to minimize risk in social interactions in which individuals perceive that the ratio of their social value to others, and their social burden on others, is at a critically low level. When this ratio reaches a point where social value and social burden are approaching equivalence, the individual is in danger of exclusion from social contexts that, over the course of evolution, have been critical to fitness. Many features of depressed states can be understood in relation to mechanisms that reduce social risk in such circumstances, including (a) hyper-sensitivity to signals of social threat from others, (b) sending signals to others that reduce social risks, and (c) inhibiting risk-seeking (e.g., confident, acquisitive) behaviors. These features are discussed in terms of psychosocial and neurobiological research on depressive phenomena.     

On the lateralization of emotional prosody: an event-related functional MR investigation

In order to investigate the lateralization of emotional speech we recorded the brain responses to three emotional intonations in two conditions, i.e., "normal" speech and "prosodic" speech (i.e., speech with no linguistic meaning, but retaining the 'slow prosodic modulations' of speech). Participants listened to semantically neutral sentences spoken with a positive, neutral, or negative intonation in both conditions and judged how positive, negative, or neutral the intonation was on a five-point scale. Core peri-sylvian language areas, as well as some frontal and subcortical areas were activated bilaterally in the normal speech condition. In contrast, a bilateral fronto-opercular region was active when participants listened to prosodic speech. Positive and negative intonations elicited a bilateral fronto-temporal and subcortical pattern in the normal speech condition, and more frontal activation in the prosodic speech condition. The current results call into question an exclusive right hemisphere lateralization of emotional prosody and expand patient data on the functional role of the basal ganglia during the perception of emotional prosody.     

What you get out of memory depends on the question you ask

Following study, participants received 2 tests. The 1st was a recognition test; the 2nd was designed to tap recollection. The objective was to examine performance on Test 1 conditional on Test 2 performance. In Experiment 1, contrary to process dissociation assumptions, exclusion errors better predicted subsequent recollection than did inclusion errors. In Experiments 2 and 3, with alternate questions posed on Test 2, words having high estimates of recollection with one question had high estimates of familiarity with the other question. Results supported the following: (a) the 2-test procedure has considerable potential for elucidating the relationship between recollection and familiarity; (b) there is substantial evidence for dependency between such processes when estimates are obtained using the process dissociation and remember-know procedures; and (c) order of information access appears to depend on the question posed to the memory system.     

Dodge-ing the issue: Dodge,Javal, Hering,and the measurement of saccades in eye-movement research

Dodge, in 1916, suggested that the French term 'saccade' should be used for describing the rapid movements of the eyes that occur while reading. Previously he had referred to these as type I movements. Javal had used the term 'saccade' in 1879, when describing experiments conducted in his laboratory by Lamare. Accordingly, Javal has been rightly credited with assigning the term to rapid eye movements. In English these rapid rotations had been called jerks, and they had been observed and measured before Lamare's studies of reading. Rapid sweeps of the eyes occur as one phase of nystagmus; they were observed by Wells in 1792 who used an afterimage technique, and they were illustrated by Crum Brown in 1878. Afterimages were used in nineteenth-century research on eye movements and eye position; they were also employed by Hering in 1879, to ascertain how the eyes moved during reading. In the previous year, Javal had employed afterimages in his investigations of reading, but this was to demonstrate that the eyes moved horizontally rather than vertically. Hering's and Lamare's auditory method established the discontinuous nature of eye movements during reading, and the photographic methods introduced by Dodge and others in the early twentieth century enabled their characteristics to be determined with greater accuracy.     

Efficacy of telephone-administered cognitive behaviour therapy for obsessive-compulsive spectrum disorders: case studies

Cognitive behaviour therapy is effective for obsessive-compulsive disorder and for obsessive-compulsive spectrum disorders such as trichotillomania. Unfortunately, many people with these disorders, especially those living in rural areas, have limited access to treatment. Telephone-administered cognitive behaviour therapy may help address this problem. In a recent study of telephone treatment for obsessive-compulsive disorder, we found that such treatment was often effective (42% in remission at post-treatment, and 47% in remission at 12-week follow-up). This article presents 2 case reports of the same treatment, applied to obsessive-compulsive spectrum disorders (trichotillomania and compulsive skin picking). Treatment was associated with symptom reduction for both participants, although one subsequently relapsed. Possible reasons for relapse are discussed. The findings encourage further studies to identify the characteristics of people most likely to benefit from telephone treatment for spectrum disorders.     

Performance of Dyslexic Children on Cerebellar and Cognitive Tests

In a previous study (A. J. Fawcett, R. I. Nicolson, & P. Dean, 1996), the authors had found strong behavioral evidence for cerebellar deficit in a panel of children with dyslexia. In the present study, the generality of those results was assessed. A battery of clinical tests for cerebellar dysfunction was administered, together with selected cognitive tests, to a further 59 dyslexic and 67 control children. The dyslexic children showed highly significant impairments on the cerebellar tests, with deficits on postural stability and muscle tone comparable in magnitude with their reading and spelling deficits. Furthermore, over 95&percent; of the dyslexic children showed clear evidence of deficit on muscle tone or stability. The findings provide further evidence of the generality of cerebellar impairment in dyslexia. The implications of the cerebellar tests for screening in dyslexia are discussed.     

"I" Value Freedom, But "We" Value Relationships: Self-Construal Priming Mirrors Cultural Differences in Judgment

The distinction between relatively independent versus interdependent self-construals has been strongly associated with several important cultural differences in social behavior. The current studies examined the causal role of self-construal by investigating whether priming independent or interdependent self-construals within a culture could result in differences in psychological worldview that mirror those traditionally found between cultures. In Experiment 1, European-American participants primed with interdependence displayed shifts toward more collectivist social values and judgments that were mediated by corresponding shifts in self-construal. In Experiment 2, this effect was extended by priming students from the United States and Hong Kong with primes that were consistent and inconsistent with their predominant cultural worldview. Students who received the inconsistent primes were more strongly affected than those who received the consistent primes, and thus shifted self-construal, and corresponding values, to a greater degree.     

Molecular geneticists and moral responsibility: “maybe if we were working on the atom bomb I would have a different argument”

Senior molecular geneticists were interviewed about their perceptions of the ethical and social implications of genetic knowledge. Inductive analysis of these interviews identified a number of strategies through which the scientists negotiated their moral responsibilities as they participated in generating knowledge that presents difficult ethical questions. These strategies included: further analysis and application of scientific method; clarification of multiple roles; negotiation with the public through public debate, institutional processes of funding, ethics committees and legislation; and personal responsibility.     

What is bioethics without Christianity?

The author uses the essays in this issue as a springboard for making three points. First, he argues that most, if not all, current institutional versions of Christianity have failed to provide a meaningful framework for the spiritual life. Second, he argues that there is no ethics other than Judeo-Christian ethics and that there can be no bioethics other than Judeo-Christian bioethics. Finally, he argues that the overriding issue we face is not whether to address bioethical issues from a Christian perspective or from a non-Christian perspective, but rather whether we shall address biological and medical issues from an ethical or a scientific-technological perspective.