Stem homographs and lemma level representations

Previous studies have found that priming a target like cerr-o ("hill") with an unmasked stem-homograph (e.g., cerr-ar, "to close") or with an unmasked allomorph of a stem-homograph (e.g., cierr-a, "he/she/it closes") has an inhibitory effect on target recognition. We report evidence from stem-homograph priming studies that implicate both morphological parsing and lexical selection processes at the lemma level. We argue that stem-homograph inhibition is the product of lexical selection mechanisms that are engaged just when a fully ambiguous stimulus (here, an inflectional stem) must be assigned one of its viable interpretations in order to afford conscious perception of lexical identity.     

Processing of temporal duration information in working memory after frontodorsal tumour excisions

This study aimed to test the hypothesis that impairments of temporal duration processing after frontal lobe lesions reflect deficits in executive monitoring functions rather than a domain-specific deficit in the maintenance of duration information in working memory. Patients with frontodorsal lesions, clinical controls with post-central lesions, and healthy controls performed recognition and classification tasks, which should allow for testing maintenance and monitoring functions, respectively. Results showed mild non-selective impairments of the frontal patients on both temporal and spatial recognition tasks, but a marked selective degradation on temporal classification while performance on spatial classification was unimpaired. This suggests that maintenance of duration information in working memory after frontal lesions is basically preserved but that, depending on executive task characteristics, there is a specific deficit in the strategic organization of this type of information.     

Priming visual face-processing mechanisms: electrophysiological evidence

Accumulated evidence from electrophysiology and neuroimaging suggests that face perception involves extrastriate visual mechanisms specialized in processing physiognomic features and building a perceptual representation that is categorically distinct and can be identified by face-recognition units. In the present experiment, we recorded event-related brain potentials in order to explore possible contextual influences on the activity of this perceptual mechanism. Subjects were first exposed to pairs of small shapes, which did not elicit any face-specific brain activity. The same stimuli, however, elicited face-specific brain activity after subjects saw them embedded in schematic faces, which probably primed the subjects to interpret the shapes as schematic eyes. No face-specific activity was observed when objects rather than faces were used to form the context. We conclude that the activity of face-specific extrastriate perceptual mechanisms can be modulated by contextual constraints that determine the significance of the visual input.     

Differential age effects for case and hue mixing in visual word recognition

The authors compare older adults' lexical-decision data with younger adults' data reported in P. Allen, A. F. Smith, et al. (2002). On the basis of their work, it was proposed that consistent-case wordswould be processed by the faster holistic (magnodominated) stream, but that mixed-case words would be processed by the slower analytic (interblob-dominated or blob-dominated) steams. Hue mixing was predicted to have no effect on consistent-case performance, but mixed-hue/mixed-case words were predicted to be recognized faster than monochrome/mixed-case words. Younger adults showed the predicted results, but older adults did not. These results suggest that holistic central processes are maintained, but that older adults exhibited an analytic decrement     

Pharmacogenetics: ethical issues and policy options

Pharmacogenetics offers the prospect of an era of safer and more effective drugs, as well as more individualized use of drug therapies. Before the benefits of pharmacogenetics can be realized, the ethical issues that arise in research and clinical application of pharmacogenetic technologies must be addressed. The ethical issues raised by pharmacogenetics can be addressed under six headings: (1) regulatory oversight, (2) confidentiality and privacy, (3) informed consent, (4) availability of drugs, (5) access, and (6) clinicians' changing responsibilities in the era of pharmacogenetic medicine. We analyze each of these categories of ethical issues and provide policy approaches for addressing them.     

The myth of Freud's ostracism by the medical community in 1896-1905: Jeffrey Masson's assault on the truth

The story recounted by Jeffrey M. Masson of the medical community's outraged response to the seduction theory is treated as historical fact in some of the recent literature on Freud's early psychoanalytic experiences. In this article the evidence adduced by Masson in The Assault on Truth (1984) to buttress his account of Freud's supposed ostracism is critically examined. It is concluded that this evidence fails to substantiate Masson's version of events, that there is abundant evidence that refutes it, and that he has ignored the historical research that demonstrates that the notion that Freud's early psychoanalytic writings received an irrationally hostile reception is a myth.     

Who is exaggerating cognitive impairment and who is not?

This chart review examined the effects of effort on neuropsychological assessment and test performance patterns among genuine and exaggerating patients, with and without neurological findings, as aids to diagnosing symptom exaggeration. The sample consisted of 561 consecutive patients involved in compensation claims. With a flexible neuropsychological test (NPT) battery, the claims were assessed over 2 days. The sample included 303 patients evaluated for traumatic brain injury, 55 patients with neurological disease, and 203 patients assessed for other conditions (eg, depression or chronic pain). An average of 38 ability measures per patient were used to generate an overall NPT domain score. Composite scores were also computed for symptom validity tests, self-report measures of psychiatric symptoms, and memory complaint inventory. Seven NPT cognitive subdomain scores were multiply regressed onto the symptom validity test composite, accounting for 45% of its total variance. Patients were also assigned to Genuine or Exaggerator groups based on symptom validity test performance. The NPT for Exaggerating patients averaged 1.43 standard deviations below that of Genuine patients, suggesting that NPT scores for most Exaggerating patients are underestimates of their true ability. Factor analysis results differed between these groups. As a result, clinicians might avoid falsely identifying genuine patients as exaggerating by incorporating their self-reports of psychiatric symptoms and memory complaints into the diagnostic process.     

Cross-cultural differences in tolerance for crowding: fact or fiction?

It is widely believed that cultures vary in their tolerance for crowding. There is, however, little evidence to substantiate this belief, coupled with serious shortcomings in the extant literature. Tolerance for crowding has been confused with cultural differences in personal space preferences along with perceived crowding. Furthermore, the few studies that have examined cultural variability in reactions to crowding have compared subgroup correlations, which is not equivalent to a statistical interaction. Although the authors found a statistical interaction indicating that Asian Americans and Latin Americans differ in the way they perceive crowding in comparison to their fellow Anglo-American and African American citizens, all four ethnic groups suffer similar, negative psychological distress sequelae of high-density housing. These results hold independently of household income.