Unimpaired attentional disengagement in toddlers with autism spectrum disorder

A prominent hypothesis holds that ‘sticky’ attention early in life in children with autism spectrum disorder (ASD) limits their ability to explore and learn about the world. Under this hypothesis, the core clinical symptoms of ASD – restricted interests, repetitive behaviors and impaired social/communication abilities – could all result from impaired attentional disengagement during development. However, the existence of disengagement deficits in children with ASD is controversial, and a recent study found no deficit in 5‐ to 12‐year‐olds with ASD. Nonetheless, the possibility remains that disengagement is impaired earlier in development in children with ASD, altering their developmental trajectory even if the attentional deficit itself is remediated or compensated for by the time children with ASD reach school age. Here, we tested this possibility by characterizing attentional disengagement in a group of toddlers just diagnosed with ASD (age 21 to 37 months). We found strikingly similar performance between the ASD and age‐matched typically developing (TD) toddlers, and no evidence of impaired attentional disengagement. These results show that even at a young age when the clinical symptoms of ASD are first emerging, disengagement abilities are intact. Sticky attention is not a fundamental characteristic of ASD, and probably does not play a causal role in its etiology.     

Contributions of facial expressions and body language to the rapid perception of dynamic emotions

Correctly perceiving emotions in others is a crucial part of social interactions. We constructed a set of dynamic stimuli to determine the relative contributions of the face and body to the accurate perception of basic emotions. We also manipulated the length of these dynamic stimuli in order to explore how much information is needed to identify emotions. The findings suggest that even a short exposure time of 250 milliseconds provided enough information to correctly identify an emotion above the chance level. Furthermore, we found that recognition patterns from the face alone and the body alone differed as a function of emotion. These findings highlight the role of the body in emotion perception and suggest an advantage for angry bodies, which, in contrast to all other emotions, were comparable to the recognition rates from the face and may be advantageous for perceiving imminent threat from a distance.     

Introducing systems change in the schools: the case of school luncheons and vending machines

A major public health crisis facing America’s society is the increase in child and youth obesity, which has seen a fourfold increase in the last four decades. Major concerns include what children eat for school lunch and what other foods are available in schools. This paper illustrates efforts towards systems change in the luncheon program and food vending machines in the Chicago Public Schools. We discuss the different factors that lead to such changes using the framework of the social ecological model and the soft systems methodology, and we analyze how the resulting innovation was implemented and evaluated. First, we present a theoretical perspective to explain factors that influence children’s eating patterns from a systems approach. Second, we discuss the antecedent factors that lead to systems change. Finally, we examine challenges to systems change, such as resistance to change, different stakeholder priorities, lack of resources, institutional bureaucracy, and unrealistic funder expectations.     

Cognitive behavioral weight-loss program for individuals with psychotic mental diseases

Overweight derived from the intake of new antipsychotic medication in order to treat schizophrenia is a growing problem. The main purpose of this study is to launch a cognitive behavioural program in outpatients. It is focused on the weight control of patients with chronic mental diseases, especially those diagnosed as psychotic, and who are under treatment in a Psychosocial Rehabilitation Centre. In this study, the results of an experimental group and a control group were compared. The experimental group was made up of 7 individuals, 3 males and 4 females, and the control group comprised 4 males and 4 females. The program had a duration of twelve sessions administered over a period of three months. Three months after concluding the program, both groups were followed up. The data obtained indicate the efficiency of the cognitive-behavioural treatment in the patients. The achievements of this project were, on the one hand, to significantly reduce the patients' weight and, on the other, to modify their nutritional and physical exercise habits.     

Temperamental and personality variables in child and adolescent depressive symptomatology

In this study, we analyzed the relationship between temperament and personality factors and depression in children and adolescents. Temperament was assessed with the Dimensions of Temperament Survey Revised (DOTS-R), personality with the Big Five Questionnaire-Children (BFQ-C), and depressive symptomatology with the Children's Depression Inventory (CDI). The sample was made up of 535 participants (274 boys and 261 girls), aged 8 to 15 years. Results show that temperament and personality are significantly related to depressive symptomatology in children and adolescents. Those with difficult temperaments showed more depressive symptomatology, as did those with high levels of emotional instability or low levels of extraversion, openness, agreeableness or conscientiousness. Multiple regression analyses revealed greater relevance of personality variables than of temperament variables.     

Comparison of impulsiveness, venturesomeness and empathy (I7) structure in English and Spanish samples: Analysis of different structural equation models

The present study analyzed the factorial structure of the I₇ Impulsiveness questionnaire (Impulsiveness, Venturesomeness and Empathy) with a Spanish sample of 742 males and 1.075 females, through exploratory and confirmatory factorial analysis. In relation to the original English data, a three-factor structure showed global congruency coefficients of 0.92 and 0.94 for men and women. Venturesomeness had a modest congruency for males (0.83). A cross-validation analytical strategy showed that the 24-item I₇ was invariant only for the female sample. A subsequent exploratory factor analysis with 24 items showed a sound factor structure. The 24-item version showed the best and most robust structure and similar internal consistency coefficients in regard to the 54-item version. No important differences were founded between I₇ long and short versions with impulsiveness scales of ZKPQ, BIS-10 and SPSRQ.     

Relationship of pain tolerance with human aggression

In research with animals as well as samples of chronic pain patients and elderly persons, pain has been positively correlated with measures of irritability, hostility, and aggression. The present investigation examined the relationship of pain tolerance with aggression. 72 men participated in the Response Choice Aggression Paradigm, described previously by Zeichner and colleagues, in which aggressive response to provocation was possible but not required of participants. Subjective pain tolerance, defined as maximal electrical shock willingly tolerated by participants, was assessed. Significant but small Pearson product-moment correlations between pain tolerance and aggression ranged between .21 and .32, with the largest accounting for 9% of variance.     

Sharing <Emphasis Type="Italic">GJB2</Emphasis>/<Emphasis Type="Italic">GJB6</Emphasis> Genetic Test Information with Family Members

Although GJB2/GJB6 genetic testing for non-syndromic hearing loss is available, there is no information regarding sharing of test results with family members. A qualitative study was conducted to elucidate if, how, and why parents of a child with hearing loss share GJB2/GJB6 test results with relatives. Parents whose child had testing (n = 7 positive, n = 4 negative, n = 1 inconclusive results) participated in a semi-structured interview and responses were analyzed using qualitative methods. All participants shared the test result with at least one relative, but selective non-disclosure also was observed. Reasons for, and reactions to, sharing were diverse and differed as a function of test result. In comparing the results from this study to published literature, similarities and differences were identified with regards to disclosure of genetic test results for hearing loss versus other conditions. Differences suggest that hearing loss may have unique attributes that influence responses to genetic test information. Further research is needed to replicate these findings.     

Amygdala upregulation of NCAM polysialylation induced by auditory fear conditioning is not required for memory formation, but plays a role in fear extinction

There is much interest to understand the mechanisms leading to the establishment, maintenance, and extinction of fear memories. The amygdala has been critically involved in the processing of fear memories and a number of molecular changes have been implicated in this brain region in relation to fear learning. Although neural cell adhesion molecules (NCAMs) have been hypothesized to play a role, information available about their contribution to fear memories is scarce. We investigate here whether polysialylated NCAM (PSA-NCAM) contributes to auditory fear conditioning in the amygdala. First, PSA-NCAM expression was evaluated in different amygdala nuclei after auditory fear conditioning at two different shock intensities. Results showed that PSA-NCAM expression was increased 24 h post-training only in animals subjected to the highest shock intensity (1mA). Second, PSA-NCAM was cleaved in the basolateral amygdaloid complex through micro-infusions of the enzyme endoneuraminidase N, and the consequences of such treatment were investigated on the acquisition, consolidation, remote memory expression, and extinction of conditioned fear memories. Intra-amygdaloid cleavage of PSA-NCAM did not affect acquisition, consolidation or expression of remote fear memories. However, intra-amygdaloid PSA-NCAM cleavage enhanced fear extinction processes. These results suggest that upregulation of PSA-NCAM is a correlate of fear conditioning that is not necessary for the establishment of fear memory in the amygdala, but participates in mechanisms precluding fear extinction. These findings point out PSA-NCAM as a potential target for the treatment of psychopathologies that involve impairment in fear extinction.     

Psychosocial stress evoked by a virtual audience: relation to neuroendocrine activity.

A modified version of the Trier Social Stress Test (TSST) was employed to determine whether exposure to a virtual audience using virtual reality (VR) technology would prompt an increase of neuroendocrine activity comparable to that prompted by a real audience. Following an anticipatory period, participants completed a speech or a speech-plus-math challenge in front of either a virtual audience, a panel of judges they were led to believe was behind a one-way mirror, or an audience comprised of confederates. An additional group that had prepared a speech was simply directed to observe the virtual audience but did not deliver the speech. Finally, a control group completed questionnaires for the duration of the experiment. Cortisol samples were obtained upon arrival to the laboratory, just before the challenge, and 15 and 30 minutes after the task. Participants also completed a measure assessing stressor appraisals of the task before and after the challenge. Anticipation of the task was associated with a modest increase of cortisol levels, and a further rise of cortisol was evident in response to the challenge. The neuroendocrine changes evoked by the virtual audience were comparable to those elicited by the imagined audience (behind the one-way mirror) but less than changes evoked by the panel of confederates. Stressor appraisals were higher post-challenge compared to those reported prior to the task; however, appraisals were similar across each group. These data suggest that VR technology may be amenable to evaluating the impact of psychosocial stressors such as the TSST.