A brainstem “mini-discharge” syndrome (anesthesia dolorosa)

Chronic pain consisting of anesthesia dolorosa secondary to bilateral interruption of the trigeminal nerves is presented as a brain stem reticular denervation syndrome. Electrothalamograms revealed fast frequency discharges in the mesothalamic prerubral and centermedian reticular formation. Mesothalamic electrical stimulation attenuated the discharges. Pain and other symptoms presumably of brainstem origin also were attenuated or abolished by therapeutic electrical stimulation twice daily. It is postulated that brain stem-represented behavioral generators are implicated by the reticular discharges in order to produce the complex symptomatology. Consequently the symptom complex is collectively identified as a brainstem “mini-discharge” syndrome. A theoretical discussion is presented to defend the thesis that reticular denervation-induced low threshold discharge system accounts for the episodic states of pain, dyskinesia, mood, and memory disturbances.     

The use of a resident daily scheduling procedure to increase appropriate social,ward, and scheduling behavior in adult psychiatric residents (patients)

The purpose of the present experiment was to investigate the efficacy of a goal orientation procedure in their treatment of apathy, isolation, and insufficient goal setting skills in chronic psychiatric residents. The experiment was conducted in a behaviorally-oriented deinstitutionalization program in a state psychiatric hospital. Three male and four female chronic psychiatric residents served as research participants. A group repeated measures design with four within-participant phases (ABA‘B’) was utilized. The goal orientation procedure included a written schedule that was completed by each research participant daily. This Daily Living Schedule required that a behavior be specified by the participant for every half-hour period during the day (8:30 a.m. to 9:00 p.m.). During all four phases of the experiment, research participants were observed on the ward from 8:30 a.m. to 12:00 noon and 1:00 p.m. to 5:00 p.m. for engagement in scheduled target behaviors. The daily scheduling procedure produced substantial increases in appropriate behavior such as social activities, ward jobs, and participation in treatment programs, whereas decrease were produced in inappropriate behavior such as isolation and day time sleeping.     

A neurophysiologic model for aggressive behavior in the cat

A neurophysiologic model for aggessive behavior in the cat is proposed. Stimulus-bound and seizure-bound aggression was evaluated in relation to limbic and basal ganglia induced seizures (after-discharges). Electrically induced limbic and basal ganglia afterdischarges were used because they are known to implicate septohypothalamic sites from which aggression can be elicited by direct stimulation. The occurrence of behavioral aggression is correlated with the discharge characteristics of a single discharging system and with two interacting discharging systems. Aggression is composed of autonomic and somato-motor components which poses relatively low and high thresholds, respectively, for their activation. Aggression occurring during a combined septum and amygdala discharge was more intense and prolonged than with a septum discharge alone. Participation of a slow frequency discharging basal ganglia system activated seizurebound aggression in an otherwise nonaggressive limbic seizure. The limbic and basal ganglia stimulations and after-discharges lowered the excitability threshold of the aggression system and made it more vulnerable to being activated by external stimuli, such as visual and auditory stimuli. These observations are reminiscent of patients with aggressive behavior associated with psychomotor seizures.     

Limbic system seizures and aggressive behavior (superkindling effects)

Integrative Psychological and Behavioral Science - This study was done to further analyze the neural mechanisms underlying aggressive behavior associated with psychomotor or temporal lobe seizures....     

Hypersexuality and limbic system seizures

Hypersexual behavior was induced in adult male cats by repeatedly evoked limbic system seizures. Accentuation of Dopaminergic activity with drugs was used to facilitate development of the seizure induced hypersexuality. Hypersexuality consisted of biting knap of neck, mounting, thrusting and coital intromission. The gradual development and eventual disappearance of hypersexuality was correlated with the progressive prolongation of the seizures in their evolution. There are three stages of seizure evolution in relation to sexuality. First stage-normal sexuality, intermediate stage-hypersexuality and late stage-hyposexuality. A theoretical “hypersexual growth and decay curve” was constructed in relation to the evolution of limbic seizure durations in the intermediate stage. It was suggested that the observed hypersexuality was related to the early discharge activation of hypothalamic, preoptic and basal ganglia neurohumeral facilitatory mechanisms for sexuality, and the late effects were related to discharge activation of brain stem serotonergic inhibitory mechanisms. The discussion attempts also to use these experimental findings to explain clinically observed hyposexuality and hypersexuality. It was suggested that either hypersexuality or hyposexuality may be associated with psychomotor seizures and that the predominating sexual state at a given moment is dependent upon the evolutionary stage of the seizure at that moment. Consequently, psychomotor seizures with associated hypersexuality should not be considered a clinical anachronism. In fact, these observations support the impression that rape may be a manifestation of a psychomotor seizure.     

‘Would it not be better to get someone out workin?’: ‘Safe prejudice’ against Polish workers

One recurring criticism of immigrant groups is their alleged failure to be employed and contribute to the host society. Here we examine how speakers mobilise a criticism that has attracted less research attention: that through their economic activity immigrant groups usurp others’ employment entitlements. Discourse analysis of data from seven focus group discussions about pre-Brexit Polish immigration into the UK, involving 31 UK nationals, shows that participants accomplish exclusionary outcomes in two divergent ways. The first attributes qualities to Polish workers but also makes explicit the consequences of these attributions for UK nationals, rendering speakers’ investment in such claims visible. The second relies on the production of category pairs, within which claims can be made for the category that excludes Polish workers. This use of categories comprises ‘safe prejudice’, a form of prejudice not previously identified but which is less open to challenge than other forms of prejudiced talk.     

Understanding fish cognition: a review and appraisal of current practices

Animal Cognition - With over 30,000 recognized species, fishes exhibit an extraordinary variety of morphological, behavioural, and life-history traits. The field of fish cognition has grown...