Life Satisfaction and Symptoms of Mental Disorder Among Older African American Public Housing Residents

This study examines life satisfaction and symptoms of mental disorder in a sample of 831 older African American residents of urban public housing developments. Symptoms of mental disorder included measures of emotional distress, alcohol-related problems, and cognitive impairment. Subjects reporting less life satisfaction had significantly greater emotional distress. Neither lifetime alcohol-related problems nor cognitive impairment were significantly related to life satisfaction. Stepwise multiple regression analyses indicated that emotional distress subscales accounted for most of the explained variance in life satisfaction. Social dysfunction was the strongest predictor of life satisfaction, accounting for 17% of the variance. Having a confidant, instrumental social support, religious support, or being female also contributed to the explained variance in life satisfaction.     

Famous personal names and the right hemisphere: the link keeps missing

In this reply to the comment by VanLancker and Ohnesorge (2002), we present the case that current evidence supports the role of left hemisphere in the recognition of famous personal names. We argue that this conclusion is in line not only with the results of Schweinberger, Landgrebe, Mohr, and Kaufmann (2002), but also with the evidence from methods other than divided visual field studies (e.g., PET and ERP studies).We show that our view is also supported by a new set of experiments that address a major concern raised by VanLancker and Ohnesorge in their comment and discuss why the evidence they present does not provide conclusive support to their right hemisphere hypothesis. One of the several possible reasons for this failure is that famous name stimuli may be less suitable than personally familiar stimuli to elicit personally relevant, affective aspects of recognition.     

Language representation in the human brain: evidence from cortical mapping

The manner in which the human brain processes grammatical-syntactic and lexical-semantic functions has been extensively debated in neurolinguistics. The discreteness and selectivity of the representation of syntactic-morphological properties in the dominant frontal cortex and the representation of the lexical-semantics in the temporo-parietal cortex have been questioned. Three right-handed adult male neurosurgical patients undergoing left craniotomy for intractable seizures were evaluated using various grammatical and semantic tasks during cortical mapping. The sampling of language tasks consisted of trials with stimulation (experimental) and without stimulation (control) from sites in the dominant fronto-temporo-parietal cortex The sampling of language implicated a larger cortical area devoted to language (syntactic-morphological and lexical-semantic) tasks. Further, a large part of the fronto-parieto-temporal cortex was involved with syntactic-morphological functions. However, only the parieto-temporal sites were implicated with the ordering of lexicon in sentence construction. These observations suggest that the representation of language in the human brain may be columnar or multilayered.     

Termination in family therapy—developing a structural approach

Termination is a neglected topic within the major schools of family therapy that draw upon systemic frameworks. This paper attempts to develop a conceptual framework for understanding termination as a process which, if handled correctly, may have a surprising degree of therapeutic potential. Termination is therefore seen not just as a passive process of ending therapy, but as a potentially empowering process which can help clients from slipping back into old ways of functioning. Follow-up sessions can therefore be reconceptualized as integral steps in an active termination process which can be extended over a number of months. The precipitate ending of sessions may be justifiable from a theoretical point.of view within certain models, but within a structural framework (which places such a strong emphasis on joining) the effects of rapid termination may not only be counter-productive but may reflect underlying problems that reflect the needs of the therapist rather than the needs of the family that is in therapy.     

Dextrorphan effects on cocaine and brainstem perturbation

Dextrorphan is a noncompetitive blocker of N-methyl-D-aspartate (NMDA) receptors. Since NMDA blockers are known to reduce the locomotor stimulatory and toxic effects of cocaine, it was speculated that dextrorphan would attenuate cocaine-induced behavioral excitatory motor activity associated with and without mechanical perturbation of the brainstem. Technique: Motor activity was recorded following dextrorphan and/or cocaine challenge in 25 SHR rats. Ten were naive subjects. Mini-osmotic pumps delivering cocaine (2.5 mg/0.49 ul/hr) were placed in 15 subjects, and infusion was halted after the third infusion day. On the fifth day either a dextrorphan (25 mg/kg, subcutaneous) or a dextrorphan and cocaine (40 mg/kg, intraperitoneal) challenge was done. Ten rats had bipolar electrode implants in the bilateral brainstem. Five were treated with DC current lesions in each of 12 days over a 3-week period. The effects of brainstem lesions on escape behavior were also evaluated in those five subjects. Results: In the naive subjects, dextrorphan reduced motor activity (P=.0001), whereas combined cocaine and dextrorphan increased motor activity (P=0.04). In lesioned subjects, dextrorphan decreased motor activity (P=0.0001). In electrode implant subjects, combined dextrorphan and cocaine challenge decreased the motor activity (P=0.04). Hyperactivity in the electrode implant group was greater than in the lesioned subjects. Midbrain electrolytic lesions attenuated escape behavior. A variety of behaviors were produced by brainstem lesions. Conclusions: Dextrorphan and brainstem lesions reduced motor hyperactivity and escape behavior. In electrode implant subjects dextrorphan counteracted the expected cocaine excitatory motor effects. Dextrorphan did not activate nor facilitate seizures.     

Limbic stimulation-induced hypersexuality

Postictal sexual drive levels induced by limbic discharges were studied in eight adult male cats. Although sexual drive was exclusively dependent upon the presence or absence of testosterone, the level or degree of drive was dependent on the relative amounts of circulating testosterone and catecholamines in addition to the bioelectric state of the testosterone-binding cells. The limbic discharge was thought to induce postictal hypersexuality by its propagated discharge, suppressing the association neocortex and simultaneously activating the sexual hormone-binding cells of the diencephalon. The dissociation of the neocortex from the diencephalon was considered as a functional postictal diaschisis. These postictal physiologic changes were thought to account for the irrational automatic behavior and memory loss characteristic of patients with psychomotor seizures.     

The rapid-smoking technique: Therapeutic effectiveness

The study examined the effectiveness of the rapid-smoking technique in terms of two measures of outcome—post-treatment abstinence rate and reduction in smoking achieved by non-abstinent subjects. A total of 75 volunteers (40 men and 35 women) participated in treatment and were randomly allocated to one of four conditions—rapid-smoking alone; rapid-smoking and relaxation training; rapid-smoking, relaxation and contingency contracting; or contingent rapid-smoking. No significant differences between treatment conditions were obtained. For the total sample, abstinence was achieved by 64% of the subjects immediately post-treatment but the probability of remaining abstinent 12 months later was only 0.33. Immediately post-treatment the non-abstinent subjects reduced their rate of cigarette consumption to 34.2% (SD = 29.3) of baseline smoking but by 12 months average consumption had increased to 82.4% (SD = 28.3) of baseline. It is concluded that rapid-smoking gives rise to substantial short-term changes in smoking behaviour but these effects are not sustained.