A neurophysiologic model for aggressive behavior in the cat

A neurophysiologic model for aggessive behavior in the cat is proposed. Stimulus-bound and seizure-bound aggression was evaluated in relation to limbic and basal ganglia induced seizures (after-discharges). Electrically induced limbic and basal ganglia afterdischarges were used because they are known to implicate septohypothalamic sites from which aggression can be elicited by direct stimulation. The occurrence of behavioral aggression is correlated with the discharge characteristics of a single discharging system and with two interacting discharging systems. Aggression is composed of autonomic and somato-motor components which poses relatively low and high thresholds, respectively, for their activation. Aggression occurring during a combined septum and amygdala discharge was more intense and prolonged than with a septum discharge alone. Participation of a slow frequency discharging basal ganglia system activated seizurebound aggression in an otherwise nonaggressive limbic seizure. The limbic and basal ganglia stimulations and after-discharges lowered the excitability threshold of the aggression system and made it more vulnerable to being activated by external stimuli, such as visual and auditory stimuli. These observations are reminiscent of patients with aggressive behavior associated with psychomotor seizures.     

Limbic system seizures and aggressive behavior (superkindling effects)

Integrative Psychological and Behavioral Science - This study was done to further analyze the neural mechanisms underlying aggressive behavior associated with psychomotor or temporal lobe seizures....     

Tripartite model of anxiety and depression: psychometric evidence and taxonomic implications

We review psychometric and other evidence relevant to mixed anxiety-depression. Properties of anxiety and depression measures, including the convergent and discriminant validity of self- and clinical ratings, and interrater reliability, are examined in patient and normal samples. Results suggest that anxiety and depression can be reliably and validly assessed; moreover, although these disorders share a substantial component of general affective distress, they can be differentiated on the basis of factors specific to each syndrome. We also review evidence for these specific factors, examining the influence of context and scale content on ratings, factor analytic studies, and the role of low positive affect in depression. With these data, we argue for a tripartite structure consisting of general distress, physiological hyperarousal (specific anxiety), and anhedonia (specific depression), and we propose a diagnosis of mixed anxiety-depression.     

Treatment of panic attacks using cognitive therapy without exposure or breathing retraining

Cognitive treatment of panic attacks is based on the hypothesis that panic results from the catastrophic misinterpretation of bodily sensations, and that changing such misinterpretations will block the occurrence of panic. The treatment normally involves an integrated set of cognitive and behavioural techniques. In a consecutive series of panic patients, a multiple baseline across subjects design was used to investigate whether a modified form of treatment involving only cognitive procedures could reduce panic attack frequency. The results provide preliminary evidence that cognitive procedures directed at changing misinterpretations of bodily sensations can reduce panic attack frequency, and also that cognitive procedures which do not target misinterpretations may not reduce panic.     

Visible persistence following a brief increment in stimulus luminance

In previous studies, it has been demonstrated that visible persistence--the period for which the perceived duration of a stimulus exceeds its physical duration--can be extended by briefly incrementing the luminance of the stimulus immediately prior to offset. Using a two-component pattern integration task, we show that this effect is not an artifact of change in the total luminous flux within the stimulus. Visible persistence was unaffected by overall luminance of the stimulus. It was also time-locked to the luminance increment. Visible persistence is seen to result from a process that is initiated by stimulus onset and that can be either wholly or partially reinitiated by the onset of the luminance increment. The duration of this process (which determines the duration of stimulus visibility) can be modified in a graded fashion by stimulus events that occur after its initiation. We outline a single-process inhibitory feedback model of the persistence mechanism that accounts for the present findings.     

Personality factors in dysphoria: A psychometric refinement of beck's Sociotropy-Autonomy Scale

The Sociotropy-Autonomy Scale (SAS) was developed as a means of assessing two cognitive-personality constructs postulated as vulnerability factors in depression (Beck, 1983). While studies have confirmed the validity of the SAS Sociotropy Scale, the construct validity of the Autonomy Scale has not been well supported. The present study was conducted to improve on the measurement of autonomy by generating additional items which were added to the original questionnaire. This 93-item SAS was administered to 485 undergraduates along with the Beck Depression Inventory, Beck Anxiety Inventory, PRF Affiliation and Autonomy Scales, Positive and Negative Emotionality Measures, and Marlowe-Crowne Social Desirability Scale. Four factors labeled Sociotropy, Solitude/Interpersonal Insensitivity, Independence, and Individualistic Achievement emerged from a principal-factor analysis of the SAS item pool. Hierarchical multiple regression analyses indicated that positive emotionality and solitude/interpersonal insensitivity were specifically related to dysphoria, while negative emotionality and sociotropy had significant associations with both anxious and depressed mood states.This research was supported by University of New Brunswick Research Grant 22–51 awarded to the first author.     

Responding to indirect speech acts

Indirect speech acts, like the request Do you know the time?, have both a literal meaning, here “I ask you whether you know the time,” and an indirect meaning “I request you to tell me the time.” In this paper I outline a model of how listeners understand such speech acts and plan responses to them. The main proposals are these. The literal meaning of indirect speech acts can be intended to be taken seriously (along with the indirect meaning) or merely pro forma. In the first case listeners are expected to respond to both meanings, as in Yes, I do—it's six, but in the second case only to the indirect meaning, as in It's six. There are at least six sources of information listeners use in judging whether the literal meaning was intended seriously or pro forma, as well as whether there was intended to be any indirect meaning. These proposals were supported in five experiments in which ordinary requests for information were made by telephone of 950 local merchants.     

Effects of genetic vestibular defects on behavior related to spatial orientation and emotionality.

A large battery of behavioral tests was administered to normal mice and to mice with varying degrees of otoconial agenesis due to genes affecting vestibular development. Many significant differences were found, but a factor analysis revealed that the variance on the 11 best tests could be accounted for in terms of two underlying variables. Factor I, the more important of the two, was associated with activity, habituation, and spontaneous alternation. Factor II appeared to represent a fear of new stimuli or situations. In both cases factor scores were highly related to the degree of otoconial deficiency. One subgroup of mice with severe otoconial agenesis displayed hyperactivity and a total absence of either habituation or spontaneous alternation. In these animals, brain and body development were stunted, and the reactions to amphetamine and physostigmine were opposite to those seen in normal mice. The results support the idea that the static organs contribute importantly to spatial orientation and suggest that early-onset vestibular defects can result in profound alterations of emotionality.