Transition to a new global paradigm of development and the role of the united nations in this process

In his 2011 Laszlo, E. (2011). Global bifurcation: The decision window. Journal of Globalization Studies, 2(2), pp. 3–6. [Google Scholar] article “Global Bifurcation: The Decision Window” Ervin Laszlo notes that “we have reached a watershed in our social and cultural evolution. The sciences of systems tell us that when complex open systems … approach a condition of critical instability, they face a moment of truth: they either transform or break down.” (p. 108) In this article we provide our own vision of this Global Bifurcation. This work stems naturally from the research highlighted in the article titled “Transition to Crisis-Free Development: A Myth or Reality?” that was published in World Futures (Bondarenko, 2014a Bondarenko, V. (2014a). Transition to crisis-free development: A myth or reality? World Futures, 70, 93–119.[Taylor &; Francis Online] , [Google Scholar]). In our new article, we move forward suggesting that crises-free development is not only possible but is also very likely, and paradoxically the world is now going through the most challenging transition from one paradigm of development to another. Based on our previous research as well as the findings of the Fifth Report to the Club of Rome, we suggest reasons for the development and implementation of a megaproject featuring a new model of life so as to make the paradigm shift possible, exclude negative implications of the upcoming technological “singularity,” and foster the achievement of an objectively defined goal of development, and this should reasonably require support from and direct involvement of the United Nations. The mechanism for implementation of this model suggests coordinating interests of the government, society, and business communities on each level with interests of particular individuals.     

SAD as a mathematical assistant—how should we go from here to there?

The System for Automated Deduction (SAD) is developed in the framework of the Evidence Algorithm research project and is intended for automated processing of mathematical texts. The SAD system works on three levels of reasoning: (a) the level of text presentation where proofs are written in a formal natural-like language for subsequent verification; (b) the level of foreground reasoning where a particular theorem proving problem is simplified and decomposed; (c) the level of background deduction where exhaustive combinatorial inference search in classical first-order logic is applied to prove end subgoals.

We present an overview of SAD describing the ideas behind the project, the system's design, and the process of problem formalization in the fashion of SAD. We show that the choice of classical first-order logic as the background logic of SAD is not too restrictive. For example, we can handle binders like Σ or lim without resort to second order or to a full-powered set theory. We illustrate our approach with a series of examples, in particular, with the classical problem .     

Post-retrieval disruption of a cocaine conditioned place preference by systemic and intrabasolateral amygdala β2- and α1-adrenergic antagonists

Previous work has demonstrated post-retrieval impairment in associative learning paradigms, including those mediated by drugs of abuse, using nonspecific β-adrenergic receptor (β-AR) antagonists. Remarkably little is known about the role of the specific β-AR subtypes, or other adrenergic receptors, in these effects. The current study examined the effects of β₁ and β₂, as well as α₁-adrenergic receptor antagonism following retrieval of a cocaine conditioned place preference (CPP). We found that rats administered the β₂ antagonist ICI 118,551 (8 mg/kg intraperitoneal [IP]) or the α₁ antagonist prazosin (1 mg/kg IP) following a drug-free test for CPP showed attenuated preference during a subsequent test, while the β₁ antagonist betaxolol (5 or 10 mg/kg IP) and a lower dose of prazosin (0.3 mg/kg IP) had no effect. Furthermore, post-test microinfusion of ICI 118,551 (6 nmol/side) or prazosin (0.5 nmol/side) into the basolateral amygdala (BLA) also impaired a subsequent preference. Systemic or intra-BLA ICI 118,551 or prazosin administered to rats in their home cages, in the absence of a preference test, had no effect on CPP 24 h later. ICI 118,551 also attenuated the FOS response in the BLA induced by the CPP test. These results are the first to demonstrate a role for α₁- and β₂-specific adrenergic mechanisms in post-retrieval memory processes. These systemic and site-specific injections, as well as the FOS immunohistochemical analyses, implicate the importance of specific noradrenergic signaling mechanisms within the BLA in post-retrieval plasticity.Substantial evidence indicates that information acquired during a learning event is initially plastic, at which time memory retention can be disrupted, but is strengthened by a time-dependent consolidation process (McGaugh 2000). Recent work has focused on retrieval-induced plasticity, a process by which changes in the retention of previously acquired information are possible. The notion of reconsolidation, one theoretical mechanism by which such changes may occur, suggests that a retrieved memory enters a labile state and is vulnerable to disruption (Sara 2000; Nader 2003). Although the theoretical mechanisms underlying reconsolidation remain unclear, the behavioral effects have been demonstrated across many different learning paradigms using a variety of pharmacological manipulations (for review, see Tronson and Taylor 2007; Diergaarde et al. 2008). Studies with aversive and appetitive preparations, including drug reward-mediated learning, have demonstrated that the noradrenergic system is important for these post-retrieval memory processes (Przybyslawski et al. 1999; Debiec and Ledoux 2004; Bernardi et al. 2006; Diergaarde et al. 2006; Robinson and Franklin 2007; Abrari et al. 2008; Fricks-Gleason and Marshall 2008; Milton et al. 2008). For example, using an animal model of cocaine-conditioned behaviors, Bernardi et al. (2006) demonstrated that systemic post-retrieval administration of propranolol impaired a subsequent conditioned place preference (CPP), suggesting that β-adrenergic receptors (β-ARs) play an important role in processes occurring following drug memory retrieval.However, most of what is known about the noradrenergic system in the memory processes that follow cued reminder trials comes from studies that use nonspecific β-AR antagonists, such as propranolol. As a consequence, several issues regarding ARs and post-retrieval memory processes remain unresolved. First, because propranolol has affinity for both β₁- and β₂-AR subtypes, it is unclear which subtype mediates these effects. To date, no studies have examined reconsolidation-like impairments using subtype-specific β-AR antagonists, which is important because more specific medications may be equally efficacious with less adverse effects. Second, no studies to date have examined α-ARs regarding a potential role in reconsolidation-like effects. α-ARs—specifically α₁-ARs—have a demonstrated role in memory consolidation (Ferry et al. 1999a,b) and may also mediate post-retrieval processes. Third, although the BLA has had a demonstrated role in reconsolidation-like effects in numerous studies, the behavioral conditions during retrieval of drug-associated memories leading to gene expression within the basolateral amygdala (BLA) have not clearly been defined. Specifically, in the CPP paradigm used here, it is unclear whether exposure to a cocaine cue alone will induce gene expression or whether a preference for the drug-associated environment needs to be expressed for BLA involvement (Franklin and Druhan 2000; Miller and Marshall 2005).Understanding the role of specific adrenergic receptors in mediating post-retrieval memory processes is particularly important in drug-induced CPP. In humans, drug-associated stimuli can facilitate drug use (Gawin 1991; See 2005) or precipitate relapse following abstinence (O''Brien et al. 1992). Thus, pharmacotherapies targeting these memory processes would benefit from a clearer understanding of the specific receptors that mediate behavioral effects (Taylor et al. 2009).Here, we first examined the effects of systemic post-test β₁-, β₂-, and α₁-AR antagonism on cocaine CPP. We then focused on the BLA due to its involvement in reconsolidation-like effects in drug learning paradigms (e.g., Lee et al. 2005), employing microinfusions of AR antagonists and measuring FOS immunoreactivity (FOS-IR) to examine the BLA as a potential site of AR-mediated impairments.     

The Russian Spinozists

The article deals with the history of Russian Spinozism in the20th century, focusing attention on three interpretations of Spinoza's philosophy – by Varvara Polovtsova, Lev Vygotsky,and Evald Ilyenkov. Polovtsova profoundly explored Spinoza'slogical method and contributed an excellent translation of histreatise De intellectus emendatione. Later Vygotsky andIlyenkov applied Spinoza's method to create activity theory,an explanation of the laws and genesis of the human mind.     

Collinearity,curvature interpolation,and the power of perceptual integration

In three experiments, participants determined the orientation of a global triangle formed by three Gabor patches of a target spatial frequency in a field of distracters. The orientation of the target patches and their proximity were varied between conditions. When all the target patches had the same orientation this facilitated the response compared to random orientations. This effect occurred only when the patches were in close proximity. When the orientations of the target patches were different but aligned to the global triangle, facilitation occurred regardless of proximity. These contrasting types of facilitation were attributed to different early perceptual integration mechanisms that enable the perception of holistic structure.     

Perceptual switching,eye movements,and the bus paradox

According to a widely cited finding by Ellis and Stark (1978 Perception 7 575-581), the duration of eye fixations is longer at the instant of perceptual reversal of an ambiguous figure than before or after the reversal. However, long fixations are more likely to include samples of an independent random event than are short fixations. This sampling bias would produce the pattern of results also when no correlation exists between fixation duration and perceptual reversals. When an appropriate correction is applied to the measurement of fixation durations, the effect disappears. In fact, there are fewer actual button-presses during the long intervals than would be expected by chance. Moving-window analyses performed on eye-fixation data reveal that no unique eye event is associated with switching behaviour. However, several indicators, such as blink frequency, saccade frequency, and the direction of the saccade, are each differentially sensitive to perceptual and response-related aspects of the switching process. The time course of these indicators depicts switching behaviour as a process of cascaded stages.     

Acculturation and adaptation of Soviet Jewish refugee adolescents: predictors of adjustment across life domains

This study explores how acculturation is related to adaptation across different life spheres for 162 Soviet Jewish refugee adolescents in a suburban community in Maryland. Because the different contexts of refugee adolescents' lives vary in acculturative demands, different patterns of acculturation should be related to adaptation in different life spheres. The study uses a multidimensional measure of acculturation and assesses acculturation to both American and Russian cultures as it relates to psychological adaptation, peer relations, and school and family outcomes. Findings support the general ecological thesis that acculturation to different cultures is differentially related to adaptation across life domains. Acculturation to American culture predicted better grades and perceived support from American peers. Acculturation to Russian culture predicted perceived support from Russian peers. Both American acculturation and Russian acculturation predicted reduced loneliness and perceived support from parents. Further, different dimensions of acculturation, such as language and identity, were differentially related to adaptation. Implications for acculturation theory and measurement are drawn, and cautions are offered about the interpretation of acculturation studies using single proxies such as language use or preference.     

Spinoza in Late-Soviet philosophy

Studies in East European Thought - This article considers the history of Soviet Spinoza studies after World War II. V.V. Sokolov, editor of the last Soviet publication of Spinoza’s...     

The acephalic community: Bataillean sovereignty,the question of relation,and the passage to the subject

Continental Philosophy Review - The present essay reconsiders Georges Bataille’s politics of the impossible in light of Jean-Luc Nancy’s and Philippe Lacoue-Labarthe’s...     

Anton Yasnitsky and René van der Veer (eds.): Revisionist revolution in Vygotsky studies

Studies in East European Thought - The authors of the volume under review proclaimed a “revisionist revolution” in Vygotsky studies. With the exception of the two chapters by Ekaterina...