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741.

Background

So far only few studies are available which have evaluated the effectiveness of psychoeducation for individuals at risk of psychosis in the early initial prodromal state (EIPS) whereas the benefit of psychoeducation in psychotic patients has been repeatedly confirmed. Thus the aim of this study was to investigate the effect of psychoeducation in individuals with increased risk of psychosis in the EIPS.

Method

A total of 128 help-seeking outpatients in the EIPS participated in a randomized controlled multicentre trial of 12 months of either psychoeducation as part of an integrated psychological intervention (IPI) or supportive counseling (SC). The time to transition to psychosis at 12-month and 24-month follow-up as well as the social adjustment at baseline, time of transition or post-treatment by means of the social adjustment scale (SAS?II) were assessed.

Results

The IPI was superior to SC in preventing progression to psychosis at 12-month (3.2% versus 16.9%, p?=0.008) and 24-month follow-up (6.3% versus 20.0%, p?=0.019). Both treatments resulted in significant pre-post improvements in SAS?II with no significant differences between the two groups.

Conclusions

Psychoeducation as part of an integrated intervention is effective for preventing the onset of psychosis over a 24-month time period in people in an EIPS. Moreover patients at risk of developing first episode psychosis seem to benefit from a specific psychoeducational intervention in the context of other treatments as well as from SC.  相似文献   
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Typischerweise liegen bei geriatrischen Patienten mehrere Erkrankungen gleichzeitig vor, die sich wechselseitig in ihrem Verlauf, aber auch in ihrer symptomatischen Auswirkung, beeinflussen. Dies gilt besonders für Zusammentreffen chronischer Schmerzen mit einer Demenz.  相似文献   
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Ohne Zusammenfassung  相似文献   
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The outcome of German serial murderer spatial decision making was measured as the straight‐line distance (km) between murderer home locations and each crime location (i.e. body recovery location). Geographic and series development data, as well as information on age, intelligence, motive, marital status, employment status, and mode of transportation of 53 German serial murderers was collected from police and prosecution service files and judicial verdict records. Potential effects of the aforementioned factors on spatial decisions were assessed. Results showed that 63% of the murderers lived within 10 km of their crime locations. Home‐to‐crime distance was negatively correlated with murderer age and positively correlated with murderer IQ score. Results also showed that the mode of transportation used by murderers had an effect on their spatial decisions. Results are discussed in terms of understanding serial murderer spatial decision‐making and implications for police investigations. Copyright © 2005 John Wiley & Sons, Ltd.  相似文献   
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ABSTRACT

Two studies demonstrate how contextual frames normalize submission and hereby complement and legitimize the exercise of power. Combining Kuhn’s qualitative concept of the self with Charles Osgood’s empirical measurements of self-attitudes, the first study tests the impact of the frame of submission on self-attitudes. This assessment of the self allows to quantify the influence of a frame or context. A second study tests the hypothesis that selves, organized by the context of submission, will normalize acts of submission. Computer simulations that quantitatively operationalize the Cybernetic Symbolic Interactionist perspective, find evidence for the normalizing quality of frames.  相似文献   
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