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22.
Short and long-term motor skill learning in an accelerated rotarod training paradigm 总被引:1,自引:0,他引:1
Rodent models of motor skill learning include skilled forelimb reaching and acrobatic locomotor paradigms. This study characterizes motor skill learning in the accelerated rotarod task. Thirty Long-Evans rats (300-400 g) were trained on an accelerated rotarod (1cm/s(2)) over eight consecutive sessions (=days, 20 trials each). Improvement in rotarod velocities mastered before falling off the rod was observed within and between sessions (plateau after five sessions). Intrasession improvement was incompletely retained at the beginning of the next day's session. Over several training sessions, intrasession improvement diminished, suggesting a ceiling effect. After 1 week of pause, the rotarod skill was retained. Locomotor exercise in a running wheel for 30 min before the first rotarod session did not affect intrasession improvement. Running-wheel exposure for 6 days did not diminish the rate of rotarod skill learning (steepness of the learning curve) but improved overall performance (upward shift of curve). Video analysis of gait on the rotarod showed that rats developed a motor strategy by modifying their gait patterns during training. The data demonstrate that rotarod improvement is not the result of enhanced general locomotor ability or fitness, which are trained in the running wheel, but requires a change in the motor strategy to master the task. Accelerated rotarod training can be regarded a valid paradigm for motor skill learning over short (intrasession, minutes) and long time frames (intersession, days). 相似文献
23.
The authors investigated whether and, if so, how velocity information is used to control predictive manual pointing movements and saccades. Participants (N = 6) intercepted an occluded moving target as if it were still visible. They kept their eyes fixated while the target moved. The target traveled over a fixed distance and changed its velocity on the way. The presentation time of the final velocity was varied. Both the eye and the hand overshot the slow target and undershot the fast target, particularly when the duration of the final velocity was short. Thus, responses were biased in the direction of the target's initial velocity. The error seemed to arise because participants did not take their latency into account when aiming at the target. Instead, they strategically aimed farther ahead when the target was fast. Amplitude was also more related to the position of velocity change than to final velocity duration. Both findings suggest that target velocity is not extrapolated but that individuals add an increment to the position of velocity change. 相似文献
24.
Frei A Schenker T Finzen A Dittmann V Kraeuchi K Hoffmann-Richter U 《Suicide & life-threatening behavior》2003,33(2):192-200
In the course of a large epidemiological study in the region of Basle, Switzerland, from 1992 to 1996, a considerable rise in suicides assisted by the right-to-die society EXIT was uncovered after wide press coverage of an assisted double suicide of a prominent couple in that region in March 1995. Further investigation revealed that the rise of assisted suicides for a period of 2 years after the critical event was statistically significant compared to the 2 years previous to the double suicide. This was especially true for women older than 65 years. Hence, the almost enthusiastic kind of reporting about this event was apt to induce imitation suicides or a "Werther-effect." 相似文献
25.
Semantic categorization in the human brain: spatiotemporal dynamics revealed by magnetoencephalography 总被引:2,自引:0,他引:2
Löw A Bentin S Rockstroh B Silberman Y Gomolla A Cohen R Elbert T 《Psychological science》2003,14(4):367-372
We examined the cortical representation of semantic categorization using magnetic source imaging in a task that revealed both dissociations among superordinate categories and associations among different base-level concepts within these categories. Around 200 ms after stimulus onset, the spatiotemporal correlation of brain activity elicited by base-level concepts was greater within than across superordinate categories in the right temporal lobe. Unsupervised clustering of data showed similar categorization between 210 and 450 ms mainly in the left hemisphere. This pattern suggests that well-defined semantic categories are represented in spatially distinct, macroscopically separable neural networks, independent of physical stimulus properties. In contrast, a broader, task-required categorization (natural/man-made) was not evident in our data. The perceptual dynamics of the categorization process is initially evident in the extrastriate areas of the right hemisphere; this activation is followed by higher-level activity along the ventral processing stream, implicating primarily the left temporal lobe. 相似文献
26.
Andreas Maercker 《Psychotherapeut》1999,44(6):381-382
Ohne Zusammenfassung 相似文献
27.
In this article we show how to extract with the use of the Buchholz-Cichon-Weiermann approach to subrecursive hierarchies from Rathjen's 1991 ordinal analysis of KPM a characterization of the provably total number-theoretic functions of KPM and some of its (most prominent) subsystems in a uniform and direct way. 相似文献
28.
Forstmeier S Maercker A Maier W van den Bussche H Riedel-Heller S Kaduszkiewicz H Pentzek M Weyerer S Bickel H Tebarth F Luppa M Wollny A Wiese B Wagner M;AgeCoDe Study Group 《Psychology and aging》2012,27(2):353-363
Midlife motivational abilities, that is, skills to initiate and persevere in the implementation of goals, have been related to mental and physical health, but their association with risk of mild cognitive impairment (MCI) and Alzheimer's disease (AD) has not yet been directly investigated. This relation was examined with data from the German Study on Ageing, Cognition, and Dementia in Primary Care Patients (AgeCoDe). A total of 3,327 nondemented participants (50.3% of a randomly selected sample) aged 75-89 years were recruited in primary care and followed up twice (after 1.5 and 3 years). Motivation-related occupational abilities were estimated on the basis of the main occupation (assessed at follow-up II) using the Occupational Information Network (O* NET) database, which provides detailed information on worker characteristics and abilities. Cox proportional hazards models were used to evaluate the relative risk of developing MCI and AD in relation to motivation-related occupational abilities, adjusting for various covariates. Over the 3 years of follow-up, 15.2% participants developed MCI and 3.0% developed AD. In a fully adjusted model, motivation-related occupational abilities were found to be associated with a reduced risk of MCI (HR: 0.77; 95% CI: 0.64-0.92). Motivation-related occupational abilities were associated with reduced risk of AD in ApoE ε4 carriers (HR: 0.48; CI: 0.25-0.91), but not in noncarriers (HR: 0.99; CI: 0.65-1.53). These results suggest that midlife motivational abilities are associated with reduced risk of MCI in general and with reduced risk of AD in ApoE ε4 carriers. Revealing the mechanisms underlying this association may inform novel prevention strategies for decelerating cognitive decline in old age. 相似文献
29.
We used the take‐the‐best heuristic to develop a model to forecast the popular two‐party vote shares in U.S. presidential elections. The model draws upon information about how voters expect the candidates to deal with the most important issue facing the country. We used cross‐validation to calculate a total of 1000 out‐of‐sample forecasts, one for each of the last 100 days of the ten U.S. presidential elections from 1972 to 2008. Ninety‐seven per cent of forecasts correctly predicted the winner of the popular vote. The model forecasts were competitive compared to forecasts from methods that incorporate substantially more information (e.g., econometric models and the Iowa Electronic Markets). The purpose of the model is to provide fast advice on which issues candidates should stress in their campaign. Copyright © 2010 John Wiley & Sons, Ltd. 相似文献
30.
Nilüfer Aydin Joachim I. Krueger Julia Fischer Dana Hahn Andreas Kastenmüller Dieter Frey Peter Fischer 《Journal of experimental social psychology》2012,48(1):446-449
A substantial amount of research shows that social exclusion is a threat to mental health. In the research reported here, we tested the hypothesis that the presence of a companion animal can serve as a buffer against these adverse effects. In a controlled laboratory experiment, we found that only socially excluded participants who did not work in the presence of a dog reported lower mental well-being compared with socially excluded participants who performed in the presence of a dog and participants who were not socially excluded. The theoretical and practical implications of these findings are discussed. 相似文献