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651.
The impact of epilepsy on quality of life (QoL) is well-documented. The ability of epileptic seizures to alter the conscious states of patients is also well established. Although there is much research on the QoL of people with epilepsy, few researchers have looked specifically at the effect of sudden, unanticipated alterations of consciousness on QoL. This lack of systematic studies of consciousness alterations and QoL in epilepsy limits our ability to shed light on this interrelation. In this article, with these limitations in mind, we focus on studies of newer AEDs. We review the evidence as to whether a significant reduction (typically more than 50%) in seizures that induce alterations of consciousness, as a result of switching to one of the newer AEDs, leads to improvements in QoL. We draw on this literature to speculate on the relationship between ictal consciousness alterations and poor QoL in epilepsy, to identify contributory and confounding factors and to highlight implications for future research. We suggest that an understanding of how factors associated with consciousness impairment affect QoL could help the treatment and management of these patients. 相似文献
652.
Andreas Karitzis 《Journal for General Philosophy of Science》2011,42(1):61-73
In this paper I question the view that realism must delineate the basic ontological furniture of the world rather than giving
arguments in semantic or epistemic terms for the existence of a mind-independent world. I call this view of stating and defending
realism the Ontological Defence of Realism (or ODR) and take Devitt’s account of realism as a paradigmatic case of ODR. I
argue that ODR cannot block ‘verificationist antirealism’ because the specific (physical) nature of what exists is not enough
to secure the mind-independence of what exists and, additionally, every element purported to achieve this, it compromises
seriously the idea that realism is primarily an ontological issue. I also stress that ODR is in tension with a plausible realist
insight namely the priority of the world over our theorizing. Because of this tension ODR weakens realism in several domains
with no good reason. Specifically, I argue that in these domains ODR faces a dilemma: either to reject realism or to take
realism to be dependent on a reductive account violating the realist insight. My point is that we should keep realism and
ontology distinct and that compliance with the realist insight initiates a better strategy for the defence of realism. I address
three possible objections thereby further clarifying my point. I conclude by presenting my view about the relation between
ontology and realism. 相似文献
653.
Eder AB Fiedler K Hamm-Eder S 《Quarterly journal of experimental psychology (2006)》2011,64(3):517-532
Three experiments investigate illusory correlations in a feedback learning paradigm. Diverging from a standard paradigm, in which stimuli consist of joint observations of group-behaviour pairs, participants were asked to guess the group reference of positive and negative stimulus behaviours. They only knew that one group was larger than the other, and the stimulus series soon revealed that positive (negative) behaviours appeared more frequently in the stimulus series than negative (positive) behaviours. Regardless of whether feedback of the actual group reference was provided or not, the predominant valence was more strongly associated with the large than the small group. This illusory-correlation effect was evident in memory-based measures at the end of the stimulus series as well as in the online predictions during stimulus presentation. The strength of illusory correlations increased with decreasing working-memory capacity, operationalized either by an interpersonal differences measure or a cognitive-load manipulation. The occurrence of illusory correlations in the absence of joint observations about group-valence pairs (in the no-feedback condition and in the early phase of the online prediction task) can be explained as a reflection of pseudocontingency inferences. 相似文献
654.
Hirschi A 《Journal of counseling psychology》2012,59(3):479-485
Scholarly interest in callings is growing, but researchers' understanding of how and when callings relate to career outcomes is incomplete. The present study investigated the possibility that the relationship of calling to work engagement is mediated by work meaningfulness, occupational identity, and occupational self-efficacy--and that this mediation depends on the degree of perceived person-job fit. I examined a highly educated sample of German employees (N = 529) in diverse occupations and found support for 2 of the 3 hypothesized mediators-work meaningfulness and occupational identity--after controlling for the relation of core self-evaluations to work engagement. Contrary to expectations, the mediated relations of callings to work engagement were not conditional upon the degree of person--job fit. The findings are considered in terms of the pathways through which callings may relate to work engagement and other career development outcomes. 相似文献
655.
Bahrami B Olsen K Bang D Roepstorff A Rees G Frith C 《Journal of experimental psychology. Human perception and performance》2012,38(1):3-8
That objective reference is necessary for formation of reliable beliefs about the external world is almost axiomatic. However, Condorcet (1785) suggested that purely subjective information--if shared and combined via social interaction--is enough for accurate understanding of the external world. We asked if social interaction and objective reference contribute differently to the formation and build-up of collective perceptual beliefs. In three experiments, dyads made individual and collective perceptual decisions in a two-interval, forced-choice, visual search task. In Experiment 1, participants negotiated their collective decisions with each other verbally and received feedback about accuracy at the end of each trial. In Experiment 2, feedback was not given. In Experiment 3, communication was not allowed but feedback was provided. Social interaction (Experiments 1 and 2 vs. 3) resulted in a significant collective benefit in perceptual decisions. When feedback was not available a collective benefit was not initially obtained but emerged through practice to the extent that in the second half of the experiments, collective benefits obtained with (Experiment 1) and without (Experiment 2) feedback were robust and statistically indistinguishable. Taken together, this work demonstrates that social interaction was necessary for build-up of reliable collaborative benefit, whereas objective reference only accelerated the process but--given enough opportunity for practice--was not necessary for building up successful cooperation. 相似文献
656.
Cooke and colleagues recently developed the lexically based model of psychopathy named the Comprehensive Assessment of Psychopathic Personality (CAPP, Cooke, Hart, Logan, & Michie, 2004). The current study was the first to evaluate aspects of the validity of a translated version of the CAPP model, which comprises 33 symptoms from six domains of personality functioning. Prototypicality ratings from 796 Norwegian community residents, forensic mental health professionals, and corrections professionals were obtained. Most CAPP symptoms were evaluated as highly prototypical of psychopathy by all three groups. Symptoms from the Self, Dominance, and Attachment domains were perceived as more prototypical than those from the Behavioral domain. Confirmatory Factor Analysis (CFA) indicated that two CAPP domains were unidimensional whereas evidence of unidimensionality was somewhat weaker for the other domains, but improved substantially after removal of problematic symptoms. Overall, the findings support the content validity of the CAPP model. This may have relevance to the current considerations regarding reformulation of the criteria for Antisocial Personality Disorder in DSM-V. 相似文献
657.
Susanna Zarafonitis Michael Wagner Verena Pützfeld Julia Berning Birgit Janssen Petra Decker Ronald Bottlender Hans-Jürgen M?ller Wolfgang Gaebel Wolfgang Maier Joachim Klosterk?tter Andreas Bechdolf 《Psychotherapeut》2012,57(4):326-334
Background
So far only few studies are available which have evaluated the effectiveness of psychoeducation for individuals at risk of psychosis in the early initial prodromal state (EIPS) whereas the benefit of psychoeducation in psychotic patients has been repeatedly confirmed. Thus the aim of this study was to investigate the effect of psychoeducation in individuals with increased risk of psychosis in the EIPS.Method
A total of 128 help-seeking outpatients in the EIPS participated in a randomized controlled multicentre trial of 12 months of either psychoeducation as part of an integrated psychological intervention (IPI) or supportive counseling (SC). The time to transition to psychosis at 12-month and 24-month follow-up as well as the social adjustment at baseline, time of transition or post-treatment by means of the social adjustment scale (SAS?II) were assessed.Results
The IPI was superior to SC in preventing progression to psychosis at 12-month (3.2% versus 16.9%, p?=0.008) and 24-month follow-up (6.3% versus 20.0%, p?=0.019). Both treatments resulted in significant pre-post improvements in SAS?II with no significant differences between the two groups.Conclusions
Psychoeducation as part of an integrated intervention is effective for preventing the onset of psychosis over a 24-month time period in people in an EIPS. Moreover patients at risk of developing first episode psychosis seem to benefit from a specific psychoeducational intervention in the context of other treatments as well as from SC. 相似文献658.
Dr. Adrian P. Mundt Marion C. Aichberger Thomas Kliewe Seda Yayla Yuriy Ignatyev Jan Mir Meryam Schouler-Ocak Markus Busch Hannah Heimann Michael Rapp Andreas Heinz Andreas Str?hle 《Psychotherapeut》2012,57(1):29-35
Background
The aim of the present study was to compare psychological distress and substance use between migrant and non-migrant populations in a socially deprived area of Berlin.Methods
A population-based random sample stratified for age (18?C57?years) and gender (50% female) was retrieved from the registration office. A total of 143 persons were included in the study. The participation rate was 48.5% when contact was established. Psychological distress was assessed using the General Health Questionnaire (GHQ-28) with its four subscales, somatic symptoms, anxiety/insomnia, social dysfunction and severe depression. Substance use was quantified using the Alcohol Use Identification Disorder Test (AUDIT) and the Fagerstr?m Test for Nicotine Dependence (FTND).Results
Of the study population 51.3% were first or second generation migrants and lived more often in single households. Migrants had lower educational levels and lower employment rates. The mean scores of migrants and non-migrants did not differ on any of the subscales somatic symptoms, anxiety/depression, social dysfunction or severe depression of the GHQ-28. Non-migrants showed significantly higher risks regarding alcohol use.Discussion
The present study did not reveal any differences regarding symptom profiles in the spectrum of anxiety and depression between non-migrants and migrants who lived in a socially deprived area. Migrants may compensate higher social risk profiles with lower risks regarding alcohol use. Larger samples have to inform on possible differences regarding smoking and other substances. 相似文献659.
Early signs of memory impairment among multiple sclerosis patients with clinically isolated syndrome
The study investigates primary and secondary verbal memory and motor/executive functions (response inhibition and strategy shifting ability) in multiple sclerosis (MS) patients with clinically isolated syndrome (CIS). We studied 44 CIS patients and compared them to 49 patients with relapsing remitting MS (RR-MS) displaying mild disability and to a large cohort of age- and education level-matched healthy volunteers(n=230). Results showed that both CIS and RR-MS patients evidenced a disproportionate impairment in the immediate and delayed recall of the second (as compared to the first) of two short narratives of the Logical Memory WMS-III subtest, and reduced performance on the Memory for Digits-Forward. Performance of either group on the executive tasks was not impaired, showing evidence of a reversed speed-accuracy trade-off. Illness duration emerged as a significant predictor of memory and executive task performance. Clinical, psychoemotional, and brain imaging findings were also examined as potential correlates of memory deficits and disease progression among CIS patients. These findings may signify early-onset decline of specific cognitive functions in CIS, which merits regular follow-up assessments and monitoring of psychoemotional adaptation and everyday functioning. 相似文献
660.
Hinz AM 《Behavioural neurology》2012,25(1):13-22
The appropriate mathematical model for the problem space of tower transformation tasks is the state graph representing positions of discs or balls and their moves. Graph theoretical quantities like distance, eccentricities or degrees of vertices and symmetries of graphs support the choice of problems, the selection of tasks and the analysis of performance of subjects whose solution paths can be projected onto the graph. The mathematical model is also at the base of a computerized test tool to administer various types of tower tasks. 相似文献