Midlife decline in declarative memory consolidation is correlated with a decline in slow wave sleep

Sleep architecture as well as memory function are strongly age dependent. Slow wave sleep (SWS), in particular, decreases dramatically with increasing age, starting already beyond the age of 30. SWS normally predominates during early nocturnal sleep and is implicated in declarative memory consolidation. However, the consequences of changes in sleep across the life span for sleep-associated memory consolidation have not been evaluated so far. Here, we compared declarative memory consolidation (for word-pair associates) during sleep in young and middle-aged healthy humans. The age groups (18–25 vs. 48–55 yr) did not differ with regard to learning performance before retention periods that covered, respectively, the first and second half of nocturnal sleep. However, after early retention sleep, where the younger subjects showed distinctly more SWS than the middle-aged (62.3 ± 3.7 min vs. 18.4 ± 7.2 min, P < 0.001), retrieval of the word pairs in the middle-aged was clearly worse than in the young (P < 0.001). In contrast, declarative memory retention did not differ between groups after late sleep, where retention was generally worse than after early sleep (P = 0.005). Retention of declarative memories was the same in both age groups when sleep periods containing equal amounts of SWS were compared, i.e., across late sleep in the young and across early sleep in the middle-aged. Our results indicate a decline in sleep-associated declarative memory consolidation that develops already during midlife and is associated with a decrease in early nocturnal SWS.     

Pain modulation during drives through cold and hot virtual environments.

Evidence exists that virtual worlds reduce pain perception by providing distraction. However, there is no experimental study to show that the type of world used in virtual reality (VR) distraction influences pain perception. Therefore, we investigated whether pain triggered by heat or cold stimuli is modulated by "warm "or "cold " virtual environments and whether virtual worlds reduce pain perception more than does static picture presentation. We expected that cold worlds would reduce pain perception from heat stimuli, while warm environments would reduce pain perception from cold stimuli. Additionally, both virtual worlds should reduce pain perception in general. Heat and cold pain stimuli thresholds were assessed outside VR in 48 volunteers in a balanced crossover design. Participants completed three 4-minute assessment periods: virtual "walks " through (1) a winter and (2) an autumn landscape and static exposure to (3) a neutral landscape. During each period, five heat stimuli or three cold stimuli were delivered via a thermode on the participant's arm, and affective and sensory pain perceptions were rated. Then the thermode was changed to the other arm, and the procedure was repeated with the opposite pain stimuli (heat or cold). We found that both warm and cold virtual environments reduced pain intensity and unpleasantness for heat and cold pain stimuli when compared to the control condition. Since participants wore a head-mounted display (HMD) in both the control condition and VR, we concluded that the distracting value of virtual environments is not explained solely by excluding perception of the real world. Although VR reduced pain unpleasantness, we found no difference in efficacy between the types of virtual world used for each pain stimulus.     

The Social Construction of Inter-Ethnic Marriages in the Greek Cypriot (GC) Republic of Cyprus: An Ethnographic Investigation of GC Male Marriages to Eastern European (EE) Females

This exploratory ethnographic investigation attempts to delve into the intrapersonal and interpersonal gender/sexual roles and marital dynamics of Greek Cypriot (GC) male marriages to Eastern European (EE) females. European Westernization and consumerism, with its increased attention on self-actualization, sexual fulfillment, material well-being, women’s rights, and men’s parental and emotional involvement, has led, over the past two decades, to a reconfiguration of the traditional GC values and beliefs concerning appropriate male and female gender/sexual roles and identities. This, in turn, has created considerable confusion over the marital roles and expectations of GC male and female partners, who seem to be waging a difficult struggle to effectively and efficiently combine Western European and GC traditional standards in their own families. Ethnographic analysis of a limited sample of 20 GC males married to EE females indicate that the former prefer EE to GC wives because of better-reported emotional, psychological, and sexual satisfaction.     

The contribution of sleep to hippocampus-dependent memory consolidation

There is now compelling evidence that sleep promotes the long-term consolidation of declarative and procedural memories. Behavioral studies suggest that sleep preferentially consolidates explicit aspects of these memories, which during encoding are possibly associated with activation in prefrontal-hippocampal circuitry. Hippocampus-dependent declarative memory benefits particularly from slow-wave sleep (SWS), whereas rapid-eye-movement (REM) sleep seems to benefit procedural aspects of memory. Consolidation of hippocampus-dependent memories relies on a dialog between the neocortex and hippocampus. Crucial features of this dialog are the neuronal reactivation of new memories in the hippocampus during SWS, which stimulates the redistribution of memory representations to neocortical networks; and the neocortical slow (<1Hz) oscillation that synchronizes hippocampal-to-neocortical information transfer to activity in other brain structures.     

Experimental comparison of dyspnea and pain

Dyspnea and pain are similarly unpleasant, alarming physical sensations, but studies examining both sensations in combination are lacking. In the present study, dyspnea was induced in 7 healthy volunteers by breathing through inspiratory resistive loads and the effects were compared with those of a heat pain stimulus. End-tidal partial pressures of carbon dioxide (PET_CO2), inspiratory time (Ti), breathing frequency (f), experienced unpleasantness, and intensity were measured. No difference was observed between dyspnea and pain in experienced intensity and unpleasantness (p >.05). During dyspneic stimulation, slightly higherTi was found than for pain (p<.08). PET_CO2 showed slight increases during the dyspneic versus the baseline and painful conditions (ΔPET_CO2=1.5 and 1.3 mmHg, respectively;p<.01 andp<.05). This study shows that the effects of dyspnea and heat pain can be compared within one experiment; both stimuli can be presented with similar intensity and unpleasantness, which is a prerequisite for comparing responses to them. The changes in PET_CO2 between our conditions were minimal, allowing an application of the present design to future fMRI studies.     

Cognitive processes in the Extrinsic Affective Simon Task: a task-set switching account of EAST effects

Recently, De Houwer (2003) introduced the Extrinsic Affective Simon Task (EAST) as a new procedure for the indirect assessment of attitudes. In the present paper, we propose an explanation of EAST effects based on a task-set switching account. Specifically, we argue that EAST effects result from difficulties in efficiently switching between two different task sets. Results from two experiments support the assumptions of the task-set switching account: While there were strong EAST effects in task-shift trials, no robust effects were found in task-repetition trials. In Experiment 2, the robustness of this task-shift effect on the EAST was demonstrated: Visual similarity between concept and attribute stimuli did not qualify the task-shift effects. Implications for the interpretation of EAST effects are discussed.     

Father-infant interaction, paternal ideas about early child care, and their consequences for the development of children's self-recognition

In this longitudinal study, the authors addressed intracultural variation on fathers' interactions with their 3-month-old infants, their ideas about parental care, and the timing of their children's self-recognition at the age of 18-20 months. Participants were 24 middle-class German fathers and their firstborn children. Two behavioral clusters emerged: a more proximal parenting style with extensive body contact and a more distal parenting style with extensive object stimulation. Fathers in the distal cluster had significantly more education than did fathers in the proximal cluster. Children who had experienced more distal parenting were more likely to recognize themselves in a mirror than were children with more proximal parenting. The authors discuss the results with respect to fathers' influence on child development and patterns of intracultural variation.     

Pre-attentive auditory processing of lexicality

The effects of lexicality on auditory change detection based on auditory sensory memory representations were investigated by presenting oddball sequences of repeatedly presented stimuli, while participants ignored the auditory stimuli. In a cross-linguistic study of Hungarian and German participants, stimulus sequences were composed of words that were language-familiar, lexical, meaningful in Hungarian but language-unfamiliar, not lexical, meaningless in German, and words with the opposite characteristics. The roles of frequently presented stimuli (Standards) and infrequently presented one (Deviants) were fully crossed. Language-familiar and language-unfamiliar Deviants elicited the Mismatch Negativity component of the event-related brain potential. We found differences in processes of change detection depending on whether the Standard was language-familiar, or not. Whereas, the lexicality of the Deviant had no effect on the processes of change detection. Also, language-familiar Standards processed differently than language-unfamiliar ones. We suggest that pre-attentive (default) tuning to meaningful words sets up language-specific preparatory processes that affect change detection in speech sequences.     

Multiple time scales in serial production of force: a tutorial on power spectral analysis of motor variability

We present a tutorial on a power spectral approach to variability in serial motor performance, describing as a case study two experiments on the form of the variance in two force production tasks. In Experiment 1 we examine grip force and load force in repetitive unimanual pulling; in Experiment 2, we describe repetitive bimanual pressing. In both experiments log-log plots of power spectral density of peak force of the responses in each stream against frequency (i.e. periodicity or repetition cycle defined with respect to the ordered succession of responses) were approximately linear with negative slopes which varied systematically with test conditions. We propose the two response streams in each experiment are associated with different levels of sustained attention and state a simple model involving summation of moving average processes on multiple time scales as a qualitative account of the changes in 1/f slope.     

Identification facilitation for emotionally arousing verbs during the attentional blink

The present study aimed to examine affective modulation of the "attentional blink" effect during rapid serial visual presentation (RSVP). Pleasant, neutral, and unpleasant written verbs were used as a 2nd target (T2) in an 8.6-Hz RSVP paradigm. Pronounced effects of 1st target (T1)-T2 stimulus onset asynchrony (SOA) were found, showing reduced report accuracy for 232- and 464-ms SOAs. Affectively arousing (pleasant and unpleasant) T2s were associated with enhanced accuracy compared with neutral T2s specifically during short (232 ms) SOAs. In contrast, pleasant and unpleasant T2s rated low in terms of emotional arousal did not show this enhancement. These results suggest that affectively arousing information is selected preferentially from a temporal stream, facilitating processes such as working memory consolidation and action.