Fostering Taiwanese preschoolers’ understanding of the addition–subtraction inverse principle

The present research involved gauging preschoolers’ learning potential for a key arithmetic concept, the addition–subtraction inverse principle (e.g., 2 + 1 − 1 = 2). Sixty 4- and 5-year-old Taiwanese children from two public preschools serving low- and middle-income families participated in the training experiment. Half were randomly assigned to an experimental group; half, to a control condition. Participants were tested for an understanding of inversion before and after intervention. One-third of the 5 year olds from both groups performed at the marginally or reliably successful levels before the intervention, and three quarters of them did so in the posttest. Only one of the 4 year olds was marginally successful before the intervention and 4 year olds in the experimental group somewhat benefited from the intervention. Significant social class effect were evident.     

Activation of amygdaloid PKC pathway is necessary for conditioned cues-provoked cocaine memory performance

Drug-associated cues are critical in reinstating the drug taking behavior even during prolonged abstinence and thus are thought to be a key factor to induce drug craving and to cause relapse. Amygdaloid complex has been known for its physiological function in mediating emotional experience storage and emotional cues-regulated memory retrieval. This study was undertaken to examine the role of basolateral nuclei of amygdala and the intracellular signaling molecule in drug cues-elicited cocaine memory retrieval. Systemic anisomycin treatment prior to the retrieval test abolished the cues-provoked cocaine conditioned place preference (CPP) memory. Likewise, a similar blockade of cues-provoked cocaine CPP performance was achieved by infusion of anisomycin and cycloheximide into the basolateral nuclei of amygdala before the test. Intra-amygdaloid infusion of H89, a protein kinase A inhibitor, or U0126, a MEK inhibitor, did not affect retrieval of the cues-elicited cocaine CPP memory. In contrast, intra-amygdaloid infusion of NPC 15437, a PKC inhibitor, abolished the cues-elicited cocaine CPP expression, while left the memory per se intact. Intra-amygdaloid infusion of NPC 15437 did not seem to affect locomotor activity or exert observable aversive effect. Taken together, our results suggest that activation of PKC signaling pathway and probably downstream de novo protein synthesis in the basolateral nuclei of amygdala is required for the cues-elicited cocaine memory performance. However, temporary inhibition of this signaling pathway does not seem to affect cocaine CPP memory per se.     

论马克思实践哲学的政治意蕴

In order to deepen the studies on the philosophy of practice, it is essential to explore the political significance of Marx's philosophy of practice. Marx's philosophy of practice is rooted in the problem of modernity and the separation between “individual subjectivity” and “societal community” in the modern context is the basic background of Marx's practical philosophy. It is the basic interest of Marx's philosophy of practice to find a way to end this separation via critique of civil society. Therefore, Marx's philosophy of practice has a clear significance, which manifests in the following aspects: one is “liberation politics,” and the other, “the regulatory mode of the socio-political institution.” Translated by Zhang Lin from Zhexue Yanjiu 哲学研究 (Philosophical Research), 2007, (1): 3–10     

What Is Integral Theory?

Integral theory is a way of knowing that helps foster the recognition that disparate aspects of reality—such as biological constitution, cultural world‐views, felt‐sense of selfhood, and social systems—are all critically important to any knowledge quest. Integral theory provides an “all quadrants, all levels” (K. Wilber, 2006, p. 26) metatheoretical framework that simultaneously honors the important contributions of a broad spectrum of epistemological outlooks while also acknowledging the parochial limits and misconceptions of those perspectives. In other words, integral theory affords a perspective that allows counselors to situate diverse knowledge approaches in such a way that they synergistically complement, rather than contradict, one another.     

医疗服务纵向整合的理论基础研究

为促进医疗服务纵向整合实践的开展, 矫正服务系统提供的碎片化服务, 结合医疗卫生服务的特点, 探讨了系统整合理论、供应链一体化管理理论、组织网络理论以及协同理论等与服务整合相关的理论基础, 着重分析了各理论的基本内涵、核心思想对医疗服务纵向整合的实践价值及其应用边界, 概括了各个服务整合相关理论内在逻辑上的关联, 最后构建了医疗服务系统纵向整合的理论模型, 以指导构建一个完整的服务连续体, 为居民提供整合的卫生服务。