La portée normative des avis d’expert dans l’élaboration de la décision administrative en matière de sécurité sanitaire

The development of scientific knowledge and the complexity of the issues of health safety have led to increase the use of expertise. The need for transparency following the “scandals” at the end of the last century has led the state to outsource its assessment procedures in health safety, by creating independent agencies. These agencies turn to outside experts because their own staff does not have all the necessary competence. So, the question is: what is the role of these experts in the elaboration of the standards made by the decisions of the agencies? The link between the decision and the expert advice may be almost considered as subordination: the administrative decision becomes stuck by the advice, due to the technical incompetence of the agency. But the circumstances of the administrative decision, especially the situation of scientific uncertainty, can impose a degree of autonomy. If the scope of expert advice seems considerable in certain aspects, it should not hide the full responsibility of policy makers.     

Moderators and mediators of remission in family-based treatment and adolescent focused therapy for anorexia nervosa

Few of the limited randomized controlled trails (RCTs) for adolescent anorexia nervosa (AN) have explored the effects of moderators and mediators on outcome. This study aimed to identify treatment moderators and mediators of remission at end of treatment (EOT) and 6- and 12-month follow-up (FU) for adolescents with AN (N = 121) who participated in a multi-center RCT of family-based treatment (FBT) and individual adolescent focused therapy (AFT). Mixed effects modeling were utilized and included all available outcome data at all time points. Remission was defined as ≥ 95% IBW plus within 1 SD of the Eating Disorder Examination (EDE) norms. Eating related obsessionality (Yale-Brown-Cornell Eating Disorder Total Scale) and eating disorder specific psychopathology (EDE-Global) emerged as moderators at EOT. Subjects with higher baseline scores on these measures benefited more from FBT than AFT. AN type emerged as a moderator at FU with binge-eating/purging type responding less well than restricting type. No mediators of treatment outcome were identified. Prior hospitalization, older age and duration of illness were identified as non-specific predictors of outcome. Taken together, these results indicate that patients with more severe eating related psychopathology have better outcomes in a behaviorally targeted family treatment (FBT) than an individually focused approach (AFT).     

Nature et significations des échanges entre domaines de vie : l’exemple des nouveaux cadres de l’Action Sociale

Accessing to a management position for the first time implies, for professionals, reflecting on their commitments in different fields and times of their socialization, on their articulation, and on their compatibilities. Referring to the model of an active socialization – active because plural and then conflicting – which rejects a dichotomous approach of the “work/non work” relations, the meaning people give to the relations between their different life spheres, communicating with others, orientates the organization of exchanges between life domains. Content analysis of interviews conducted with new social work managers brought us to distinguish six types of exchanges: temporal, informational, relational, emotional, axiological, ideological and symbolic.     

Personality Development at Work: Workplace Conditions,Personality Changes,and the Corresponsive Principle

Investigations concerning adult personality development have increasingly focused on factors that are associated with apparent personality trait changes. The current study contributes to this literature by replicating and extending previous research concerning personality trait development in young adulthood and perceptions of workplace conditions. Analyses were based on up to 442 individuals who participated in the ongoing Family Transitions Project (e.g., Conger & Conger, 2002). The current analyses included personality trait data from 1994 and 2003, high school grades and socioeconomic status indicators from 1994, and reports about work conditions in 2001, 2003, and 2005. Personality attributes were prospectively associated with work conditions and income. Findings also support the corresponsive principle of personality development (e.g., Roberts, Caspi, & Moffitt, 2003): Traits that were prospectively associated with particular workplace conditions often seemed to be accentuated by those conditions. Personality traits are prospectively associated with perceptions of the workplace. Workplace conditions are also associated with trait development.     

Selfishness,Altruism, and our Future Selves

In this article, I defend the thesis that selfishness and altruism can be intrapersonal. In doing so, I argue that the notions of intrapersonal altruism and selfishness usefully pick out behavioural patterns and have predictive value. I also argue that my thesis helps enrich our understanding of the prudential, and can subsume some interesting work in economic and psychological theory.     

Apraxia and Alzheimer’s Disease: Review and Perspectives

Apraxia is one of the cognitive deficits that characterizes Alzheimer’s disease. Despite its prevalence and relevance to diagnosing Alzheimer’s disease, this topic has received little attention and is without comprehensive review. The review herein is aimed to fill this gap by first presenting an overview of the impairment caused in different clinical situations: pantomime of tool use, single tool use, real tool use, mechanical problem solving, function and manipulation knowledge tasks, and symbolic/meaningless gestures. On the basis of these results, we then propose alternative interpretations regarding the nature of the underlying mechanisms impaired by the disease. Also presented are principal methodological issues precluding firm conclusions from being drawn.     

Religiousness and Depressive Symptoms in Five Ethnic Adolescent Groups

This study examined the relation between religiousness and depressive symptoms in African American, Asian American, European American, Hispanic American, and Native American adolescents (N = 13,317) in the United States with self-esteem and school attachment as potential mediators in this link. The data were taken from a nationally represented sample of adolescents in Grades 7 through 12, from the National Longitudinal Study of Adolescent Health (Add Health). Structural equation analyses with measurement and structural invariance across the five ethnic groups and gender supported the model that religiousness, as a composite of internal and external religiousness items, negatively predicted depressive symptoms 1 year later controlling for baseline depressive symptoms. Self-esteem and school attachment partially mediated this link but only for European American and African American adolescents.     

Relative category-specific preservation in semantic dementia? Evidence from 35 cases

Category-specific deficits have rarely been reported in semantic dementia (SD). To our knowledge, only four previous studies have documented category-specific deficits, and these have focused on the living versus non-living things contrast rather than on more fine-grained semantic categories. This study aimed to determine whether a category-specific effect could be highlighted by a semantic sorting task administered to 35 SD patients once at baseline and again after 2 years and to 10 Alzheimer’s disease patients (AD). We found a relative preservation of fruit and vegetables only in SD.This relative preservation of fruit and vegetables could be considered with regard to the importance of color knowledge in their discrimination. Indeed, color knowledge retrieval is known to depend on the left posterior fusiform gyrus which is relatively spared in SD. Finally, according to predictions of semantic memory models, our findings best fitted the Devlin and Gonnerman’s computational account.     

Why the Standard View of Ignorance Prevails

Rik Peels has forcefully argued that, contrary to what is widely held, ignorance is not equivalent to the lack or absence of knowledge. In doing so, he has argued against the Standard View of Ignorance according to which they are equivalent, and argued for what he calls “the New View” according to which ignorance is equivalent (merely) to the lack or absence of true belief. In this paper, I defend the Standard View against Peels’s latest case for the New View.     

Treadmill performance of mice with cerebellar lesions: 2. Lurcher mutant mice

The sensorimotor skills of a spontaneous mouse mutant with cerebellar cortical atrophy, Lurcher, were examined on either a fast or a slow treadmill inclined at one of three slopes, requiring forward movements in order to avoid footshocks. During the early part of acquisition, Lurcher mutants had lower latencies before falling on either treadmill than normal mice, but not during a retention test. For both Lurcher mutants and controls, the amount of time spent walking as a function of time spent on the belt increased with an increase in belt speed. Lurcher mutants had higher walking time/total time ratios on the slow but not on the fast treadmill. It is concluded that cerebellar cortical degeneration impaired the time course of acquisition but not long-term retention of the treadmill task.