Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH⁺, and 10 without, WMH⁻) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH⁺ and WMH⁻ - in right parietal and bilateral temporal areas. Both WMH⁻ and WMH⁺ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH⁺ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.     

Evidence-Based Assessment in Children and Adolescents with Obsessive–Compulsive Disorder

The assessment of varied psychiatric disorders, including obsessive–compulsive disorder (OCD), is shifting towards the use of evidence-based assessments (EBAs). This shift has fostered the development, validation and adaptation of several measures to rate obsessive–compulsive symptoms and other related problematic areas such as functional impairment or family attitudes among others. The aim of this paper is to present a systematic review of psychometric studies on pediatric OCD-specific measures to classify these according to assessment evidence-based criteria. Selection criteria that determined which studies were included in the review were: (1) analyzing an OCD measure and (2) including participants’ age being 18 years or younger. The literature search procedure was conducted in Medline, PsycINFO, PsycARTICLES, ERIC, Cochrane Library, and Scholar Google databases and enabled us to locate 42 studies which analyzed psychometric properties of 14 OCD measures studied in children and adolescents. Instruments were grouped into the following assessment areas: symptom presence and severity, functional impairment, family functioning and cognitive dimensions of OCD. Psychometric data regarding internal structure, internal consistency, reliability, validity and diagnostic precision were also reported. Further, measures were classified as well-established, approaching well-established and promising assessments in terms of reliability and validity. We concluded that the assessment of OCD in pediatric populations is a growing field that in a short-medium term could provide a wide variety of EBAs for the evaluation obsessive–compulsive symptoms and other OCD-related dimensions. The paper concludes by highlighting directions for future research.     

The impact of subjective recognition experiences on recognition heuristic use: A multinomial processing tree approach

The recognition heuristic (RH) theory states that, in comparative judgments (e.g., Which of two cities has more inhabitants?), individuals infer that recognized objects score higher on the criterion (e.g., population) than unrecognized objects. Indeed, it has often been shown that recognized options are judged to outscore unrecognized ones (e.g., recognized cities are judged as larger than unrecognized ones), although different accounts of this general finding have been proposed. According to the RH theory, this pattern occurs because the binary recognition judgment determines the inference and no other information will reverse this. An alternative account posits that recognized objects are chosen because knowledge beyond mere recognition typically points to the recognized object. A third account can be derived from the memory-state heuristic framework. According to this framework, underlying memory states of objects (rather than recognition judgments) determine the extent of RH use: When two objects are compared, the one associated with a “higher” memory state is preferred, and reliance on recognition increases with the “distance” between their memory states. The three accounts make different predictions about the impact of subjective recognition experiences—whether an object is merely recognized or recognized with further knowledge—on RH use. We estimated RH use for different recognition experiences across 16 published data sets, using a multinomial processing tree model. Results supported the memory-state heuristic in showing that RH use increases when recognition is accompanied by further knowledge.     

From species ethics to social concerns: Habermas’s critique of “liberal eugenics” evaluated

Three arguments of Habermas against “liberal eugenics”—the arguments from consent, responsibility, and instrumentalization—are critically evaluated and explicated in the light of his discourse ethics and social theory. It is argued that these arguments move partly at a too deep level and are in part too individualistic and psychological to sufficiently counter the liberal position that he sets out to criticize. This is also due to limitations that prevent discourse ethics from connecting effectively to the moral and political domains, e.g., through a discussion of justice. In spite of these weaknesses, Habermas’s thesis is of major relevance and brings up neglected issues in the discussion about eugenic reproductive practices. This relevance has not been duly recognized in bioethics, largely because of the depth of his speculations of philosophical anthropology. It is argued that Habermas’s notion of the colonization of the lifeworld could provide the analytical tool needed to build that bridge to the moral and political domain.     

Evaluation of Affect in Mexico and Spain: Psychometric Properties and Usefulness of an Abbreviated Version of the Day Reconstruction Method

The aims of the present study were to assess the psychometric properties of the Spanish-language version of the abbreviated Day Reconstruction Method (DRM), and to investigate differences in affective experience in Mexico and Spain. A total of 2,629 adults from Mexico and 4,583 from Spain were interviewed. Information was obtained using an abbreviated version of the DRM, which had been translated into Spanish. Reliability, validity, and the structure of affect were assessed and compared between countries. The diurnal variation of affect, the changes in affect along the life span, time use, and the relationship between affect and socio-demographic characteristics were also analysed. Adequate psychometric properties for the Spanish-language version of the abbreviated DRM were found in both the Mexican and the Spanish samples, and affect tended to improve along the life span in both countries. However, net affect did not have the same distribution function (Kolmogorov–Smirnov statistic = 0.25, p < 0.001) in both countries, being higher in Spain. Moreover, both samples showed opposite patterns in the diurnal variation of affect. The results showed that the Spanish-language version of the DRM is a feasible and valid method to measure affect, its diurnal rhythms, and time use in large-scale surveys.     

Gaze-following behind barriers in domestic dogs

Although gaze-following abilities have been demonstrated in a wide range of species, so far no clear evidence has been available for dogs. In the current study, we examined whether dogs follow human gaze behind an opaque barrier in two different contexts, in a foraging situation and in a non-foraging situation (food involved vs. food not involved in the situation). We assumed that dogs will spontaneously follow the human gaze and that the foraging context will have a positive effect on dogs’ gaze-following behaviour by causing an expectation in the dogs that food might be hidden somewhere in the room and might be communicated by the experimenter. This expectation presumably positively affects their motivational and attentional state. Here, we report that dogs show evidence of spontaneous gaze-following behind barriers in both situations. According to our findings, the dogs gazed earlier at the barrier in the indicated direction in both contexts. However, as we expected, the context also has some effect on dogs’ gaze-following behaviour, as more dogs gazed behind the barrier in the indicated direction in the foraging situation. The present results also support the idea that gaze-following is a characteristic skill in mammals which may more easily emerge in certain functional contexts.     

Effects of training condition on the contribution of specific items to relational processing in baboons (Papio papio)

Relational processing involves learning about the relationship between or among stimuli, transcending the individual stimuli, so that abstract knowledge generalizable to novel situations is acquired. Relational processing has been studied in animals as well as in humans, but little attention has been paid to the contribution of specific items to relational thinking or to the factors that may affect that contribution. This study assessed the intertwined effects of item and relational processing in nonhuman primates. Using a procedure that entailed both expanding and contracting sets of pictorial items, we trained 13 baboons on a two-alternative forced-choice task, in which they had to distinguish horizontal from vertical relational patterns. In Experiment 1, monkeys engaged in item-based processing with a small training set size, and they progressively engaged in relation-based processing as training set size was increased. However, in Experiment 2, overtraining with a small stimulus set promoted the processing of item-based information. These findings underscore similarities in how humans and nonhuman primates process higher-order stimulus relations.     

What chance-credence norms should be

Synthese - Multiple realizability says that the same kind of mental states may be manifested by systems with very different physical constitutions. Putnam (1967) supposed it to be...     

Longitudinal Associations Between the Five-Factor Model of Personality and The Bi-Factor Model of Psychopathology: Continuity,Pathoplasty and Complication Effects in Adolescents

The study of the bifactor structure of psychopathology, which includes a general factor of psychopathology (or p factor) in addition to the internalizing and externalizing factors, has gained attention. However, its associations with the Five-Factor Model (FFM) of personality has been addressed in few studies, and none has examined different plausible etiological models (i.e., continuity, pathoplasty, complication) to explain its relationship, which is the aim of the present research. Additionally, the longitudinal association of the General Factor of Personality (GFP) and the p factor will be also explored. Personality and psychopathological symptoms of high school students were assessed at three time points (once a year) (n?=?655; M?=?13.79, SD?=?1.24; 49.8% girls). Confirmatory Factor Analysis (and measurement invariance across waves) were tested for the traits, the GFP and the bifactor model of psychopathology. While the bifactor model and the one-factor solution for each personality trait displayed good fit to the data and remained invariant over time, the structure of the GFP was adequate and invariant in two of the three waves. The resulting factors were included in cross-lagged panel models and showed that the FFM traits and the psychopathology factors influenced each other reciprocally. Most associations fell in line with the continuity model, but minor pathoplastic and complication effects were also reported. Similar associations were found between the GFP and the p factor. These results suggest that interventions in riskier personality profiles might prevent the development of general and more specific psychopathology spectra.

     

Early emotional memories and well-being in adolescence: The roles of shame and self-critical attitudes

Journal of Child and Family Studies - Some studies have demonstrated the link between the recall of early affiliative experiences and psychopathological symptoms in adolescence. However, literature...