Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

Exposure to severe air pollution produces neuroinflammation and structural brain alterations in children. We tested whether patterns of brain growth, cognitive deficits and white matter hyperintensities (WMH) are associated with exposures to severe air pollution. Baseline and 1 year follow-up measurements of global and regional brain MRI volumes, cognitive abilities (Wechsler Intelligence Scale for Children-Revised, WISC-R), and serum inflammatory mediators were collected in 20 Mexico City (MC) children (10 with white matter hyperintensities, WMH⁺, and 10 without, WMH⁻) and 10 matched controls (CTL) from a low polluted city. There were significant differences in white matter volumes between CTL and MC children - both WMH⁺ and WMH⁻ - in right parietal and bilateral temporal areas. Both WMH⁻ and WMH⁺ MC children showed progressive deficits, compared to CTL children, on the WISC-R Vocabulary and Digit Span subtests. The cognitive deficits in highly exposed children match the localization of the volumetric differences detected over the 1 year follow-up, since the deficits observed are consistent with impairment of parietal and temporal lobe functions. Regardless of the presence of prefrontal WMH, Mexico City children performed more poorly across a variety of cognitive tests, compared to CTL children, thus WMH⁺ is likely only partially identifying underlying white matter pathology. Together these findings reveal that exposure to air pollution may perturb the trajectory of cerebral development and result in cognitive deficits during childhood.     

Predicting premature termination within a randomized controlled trial for binge-eating patients

Understanding the dropout rates of efficacious forms of psychotherapy for patients with binge eating disorder (BED) is an unsolved problem within this increasing population. Up until now the role of psychotherapy process characteristics as predictors of premature termination has not been investigated in the BED literature. Within a randomized controlled trial (N=78) we investigated the degree to which early psychological process characteristics, such as components of the therapeutic relationship and the experiences of mastery and motivational clarification, predicted premature termination of treatment. We statistically controlled for the influences of covariates such as rapid response of treatment, treatment group, body mass index, Axis II disorder, and patients' preexisting generalized self-efficacy at baseline. Patients' postsession reports from Sessions 1 to 5 indicated that low self-esteem in-session experiences was a stable predictor of premature termination. Its predictive value persisted after controlling for the above-mentioned covariates. Exploratory analyses further revealed low self-esteem experiences, low global alliance, and low mastery and clarification experiences as predictors in those patients who explicitly specified discontentment with therapy as reason for premature termination. These results indicate that patients' self-esteem experiences may not be an epiphenomenon of their specific psychopathology but may represent general mechanisms on which remaining or withdrawing from psychotherapeutic treatment depends. Early psychotherapy process characteristics should therefore be considered in training and evaluation of psychotherapists carrying through BED treatments.     

Spanish validation of the Acceptance of Modern Myths about Sexual Aggression scale (AMMSA)

Two studies were conducted with college students to validate the Spanish-language version of the "Acceptance of Modern Myths about Sexual Aggression" scale (AMMSA) (Gerger, Kley, Bohner & Siebler, 2007). This scale assesses modern myths about sexual aggression in a subtle way. In Study 1, 305 students completed the Spanish AMMSA and other scales with related content. In Study 2, 263 participants completed the Spanish AMMSA and answered questions about a hypothetical sexual assault perpetrated by a young man against a female acquaintance. The Spanish AMMSA showed high internal consistency and adequate evidence of validity in both studies. Compared to traditional scales of rape myth acceptance, mean scores on the AMMSA were higher and their distributions more closely approximated normality. These findings suggest that the Spanish version of the AMMSA scale is a useful instrument to study the social perception of sexual aggression.     

Death anxiety and death obsession in Spanish students

This study examined the dimensional structure of Templer's Death Anxiety Scale and Abdel-Khalek's Death Obsession Scale. The responses of 289 Spanish students to the Spanish forms of both scales were evaluated by means of a principal components analysis with varimax rotation. Three significant factors were identified: Death Obsession, Cognitive-Affective, and Death Anxiety. The distribution of the factor loadings for the items of both scales on Factors 1 and 3 supported the discriminant validity of the constructs specific to each of the scales, while Factor 2 showed a common component in both scales characterized by cognitive and affective aspects in relation to the idea of death.     

Acquisition, learning, or development of language? Skinner's "Verbal Behavior" revisited

In 1957, Skinner, in his "Verbal Behavior", proposed an explanation on how a language is learned. In 1959, Chomsky strongly argued the non-learnability of language, establishing in the field of developmental psycholinguistics the substitution of the term "learning" for that of "acquisition". Currently, the constructivist models describe language acquisition as a process of ontogenetic, gradual, complex, and adaptive change. This new theoretical framework has been especially useful for rereading Verbal Behavior because it facilitates recovering the Skinnerian learning mechanisms. This can be observed in the recent research trends that recapture reinforcement and imitation (echoic responses), although they are now located in the initial phases of the process and are included in a cognitive dynamic that, by gradually increasing its complexity, can achieve grammar. The new constructivist theoretical framework, by retrieving the functional and referential aspects of language, can also take advantage of the classic Skinnerian proposal about the pragmatic types of verbal behavior, providing it with new meaning.     

Tinnitus als soziale Infektion?

Background

11 out of 35 male employees of a central alert team with rescue coordination function developed a tinnitus disorder. This clinical case-study highlights the psychodynamic background of this accumulation.

Methods

Employees were investigated by psychometric questionnaires and semistructured psychodynamic biografical interviews. Additionally aspects of group dynamics and organisational structure were assessed.

Results

All staff members reported adverse work conditions. Medical and psychometric examination of the tinnitus patients did not reveal severe pathological findings. The interviews identified psychodynamic conflicts dealing with autonomy and regulation of self-esteem. All tinnitus patients reported a very adverse or punitive father relation and difficulties in performing a stabile male role and self-image. Group dynamics was dominated by paranoid and regressive tendencies complicated by maladaptive coping, crude perception of external facts and a pronounced experience of aggressive impulses.

Conclusion

The remobilisation of infantile powerlessness, ineffectiveness and helplessness triggered by adverse work conditions and the introduction of a new culture of personal responsibility within the work organisation together with an impaired coping of separation conflicts enforced by traumatic aspects of the relation with the father may have promoted the tinnitus symptomatology. Additionally, due to the missing awareness of the importance of such group dynamical processes the employers contributed to an increasing psychosocial distress, which promoted the accumulated manifestation of tinnitus as a conflict expressive symptom.     

The frequency effect for pseudowords in the lexical decision task

Four experiments were designed to investigate whether the frequency of words used to create pseudowords plays an important role in lexical decision. Computational models of the lexical decision task (e.g., the dual route cascaded model and the multiple read-out model) predict that latencies to low-frequency pseudowords should be faster than latencies to high-frequency pseudowords. Consistent with this prediction, results showed that when the pseudowords were created by replacing one internal letter of the base word (Experiments 1 and 3), high-frequency pseudowords yielded slower latencies than low-frequency pseudowords. However, this effect occurred only in the leading edge of the response time (RT) distributions. When the pseudowords were created by transposing two adjacent internal letters (Experiment 2), high-frequency pseudowords produced slower latencies in the leading edge and in the bulk of the RT distributions. These results suggest that transposed-letter pseudowords may be more similar to their base words than replacement-letter pseudowords. Finally, when participants performed a go/no-go lexical decision task with one-letter different pseudowords (Experiment 4), high-frequency pseudowords yielded substantially faster latencies than low-frequency pseudowords, which suggests that the lexical entries of high-frequency words can be verified earlier than the lexical entries of low-frequency words. The implications of these results for models of word recognition and lexical decision are discussed.     

Human listeners are able to classify dog (Canis familiaris) barks recorded in different situations

The authors investigated whether human listeners could categorize played-back dog (Canis familiaris) barks recorded in various situations and associate them with emotional ratings. Prerecorded barks of a Hungarian herding dog breed (Mudi) provided the sample. Human listeners were asked to rate emotionality of the vocalization and to categorize the situations on the basis of alternative situations provided on a questionnaire. The authors found almost no effect of previous experience with the given dog breed or of owning a dog. Listeners were able to categorize bark situations high above chance level. Emotionality ratings for particular bark samples correlated with peak and fundamental frequency and interbark intervals. The authors did not find a significant effect of tonality (harmonic-to-noise ratio) on either the emotionality rating or situation categorization of the human listeners. Humans' ability to recognize meaning suggests that barks could serve as an effective means of communication between dog and human.